{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T19:20:04Z","timestamp":1771615204737,"version":"3.50.1"},"reference-count":39,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"national funds (OE)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Cancer is one of the leading causes of death worldwide. Conventional treatments such as surgery, chemotherapy, and radiotherapy have limitations and severe side effects. Magnetic hyperthermia (MH) is an alternative method that can be used alone or in conjunction with chemotherapy or radiotherapy to treat cancer. Cobalt ferrite particles were synthesized using an innovative biogenic sol\u2013gel method with powder of coconut water (PCW). The obtained powders were subjected to heat treatments between 500 \u00b0C and 1100 \u00b0C. Subsequently, they were characterized by thermal, structural, magnetic, and cytotoxic analyses to assess their suitability for MH applications. Through X-ray diffraction and Raman spectroscopy, it was possible to confirm the presence of the pure phase of CoFe2O4 in the sample treated at 1100 \u00b0C, exhibiting a saturation magnetization of 84 emu\/g at 300 K and an average grain size of 542 nm. Furthermore, the sample treated at 1100 \u00b0C showed a specific absorption rate (SAR) of 3.91 W\/g, and at concentrations equal to or below 5 mg\/mL, is non-cytotoxic, being the most suitable for biomedical applications.<\/jats:p>","DOI":"10.3390\/molecules28237737","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T11:31:25Z","timestamp":1700739085000},"page":"7737","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cobalt Ferrite Synthesized Using a Biogenic Sol\u2013Gel Method for Biomedical Applications"],"prefix":"10.3390","volume":"28","author":[{"given":"Patr\u00edcia","family":"Gomes","sequence":"first","affiliation":[{"name":"i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7626-0210","authenticated-orcid":false,"given":"B\u00e1rbara","family":"Costa","sequence":"additional","affiliation":[{"name":"i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2416-9081","authenticated-orcid":false,"given":"Jo\u00e3o P. F.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4975-7480","authenticated-orcid":false,"given":"Paula I. P.","family":"Soares","sequence":"additional","affiliation":[{"name":"CENIMAT, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"given":"T\u00e2nia","family":"Vieira","sequence":"additional","affiliation":[{"name":"CENIMAT\/i3N, Department of Physics, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"given":"C\u00e9lia","family":"Henriques","sequence":"additional","affiliation":[{"name":"CENIMAT\/i3N, Department of Physics, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9039-2199","authenticated-orcid":false,"given":"Manuel Almeida","family":"Valente","sequence":"additional","affiliation":[{"name":"i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4084-5764","authenticated-orcid":false,"given":"S\u00edlvia Soreto","family":"Teixeira","sequence":"additional","affiliation":[{"name":"i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. 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