{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:45:49Z","timestamp":1775695549864,"version":"3.50.1"},"reference-count":28,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"ValICET","award":["PRIMA\/0001\/2020"],"award-info":[{"award-number":["PRIMA\/0001\/2020"]}]},{"name":"ValICET","award":["UIDB\/00211\/2020"],"award-info":[{"award-number":["UIDB\/00211\/2020"]}]},{"name":"FCT\/MCTES","award":["PRIMA\/0001\/2020"],"award-info":[{"award-number":["PRIMA\/0001\/2020"]}]},{"name":"FCT\/MCTES","award":["UIDB\/00211\/2020"],"award-info":[{"award-number":["UIDB\/00211\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Citrus medica L. is a traditional citrus fruit that is rich in bioactive compounds and has the potential to be used as a natural source of food additives. This study aims to evaluate the antioxidant capacity and characterize the phenolic compounds present in the peels (including flavedo and albedo), pulp, and seeds of citron. The results showed that, compared to the other parts, the pulp had a substantially higher Antioxidant Activity Coefficient (AAC) of 168.2. The albedo and the seeds had significantly lower AAC values, while the green and yellow flavedo showed noteworthy results. O-coumaric acid was the predominant phenolic acid in all of the citron fractions; it was found in the highest concentration in albedo (37.54 \u00b5g\/g FW). Flavanones and flavanols were the primary flavonoids in the pulp, peel, and seeds, with total flavonoid concentration ranging from ~9 \u00b5g\/g FW in seeds to 508 \u00b5g\/g FW in the pulp. This research offers significant insights into the antioxidant properties of this ancient fruit, emphasizing its potential applications as a natural source of antioxidants to be used in different applications.<\/jats:p>","DOI":"10.3390\/molecules29153533","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T09:50:05Z","timestamp":1722246605000},"page":"3533","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Unlocking the Potential of Citrus medica L.: Antioxidant Capacity and Phenolic Profile across Peel, Pulp, and Seeds"],"prefix":"10.3390","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4490-5202","authenticated-orcid":false,"given":"Ana Rita Soares","family":"Mateus","sequence":"first","affiliation":[{"name":"INIAV\u2014National Institute for Agricultural and Veterinary Research, I.P., Rua dos Lagidos, Lugar da Madalena, Vair\u00e3o, 4485-655 Vila do Conde, Portugal"},{"name":"University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de St\u00aa Comba, 3000-548 Coimbra, Portugal"},{"name":"LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de St\u00aa Comba, 3000-548 Coimbra, Portugal"},{"name":"CECA\u2014Centre for Animal Science Studies, ICETA, 4099-002 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7849-4379","authenticated-orcid":false,"given":"Jo\u00e3o David","family":"Teixeira","sequence":"additional","affiliation":[{"name":"INIAV\u2014National Institute for Agricultural and Veterinary Research, I.P., Rua dos Lagidos, Lugar da Madalena, Vair\u00e3o, 4485-655 Vila do Conde, Portugal"},{"name":"CECA\u2014Centre for Animal Science Studies, ICETA, 4099-002 Porto, Portugal"},{"name":"University of Minho, Department of Chemistry, Largo do Pa\u00e7o, 4704-553 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8017-5668","authenticated-orcid":false,"given":"S\u00edlvia Cruz","family":"Barros","sequence":"additional","affiliation":[{"name":"INIAV\u2014National Institute for Agricultural and Veterinary Research, I.P., Rua dos Lagidos, Lugar da Madalena, Vair\u00e3o, 4485-655 Vila do Conde, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0175-1119","authenticated-orcid":false,"given":"Carina","family":"Almeida","sequence":"additional","affiliation":[{"name":"INIAV\u2014National Institute for Agricultural and Veterinary Research, I.P., Rua dos Lagidos, Lugar da Madalena, Vair\u00e3o, 4485-655 Vila do Conde, Portugal"},{"name":"LEPABE\u2014Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"},{"name":"AliCE\u2014Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0000-7387","authenticated-orcid":false,"given":"S\u00f3nia","family":"Silva","sequence":"additional","affiliation":[{"name":"INIAV\u2014National Institute for Agricultural and Veterinary Research, I.P., Rua dos Lagidos, Lugar da Madalena, Vair\u00e3o, 4485-655 Vila do Conde, Portugal"},{"name":"Centre of Biological Engineering, 4710-057 Braga, Portugal"},{"name":"LABBELS\u2014Associate Laboratory, 4710-057 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0226-921X","authenticated-orcid":false,"given":"Ana","family":"Sanches-Silva","sequence":"additional","affiliation":[{"name":"University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de St\u00aa Comba, 3000-548 Coimbra, Portugal"},{"name":"CECA\u2014Centre for Animal Science Studies, ICETA, 4099-002 Porto, Portugal"},{"name":"Al4AnimalS\u2014Associate Laboratory for Animal and Veterinary Sciences, 1300-477 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"110909","DOI":"10.1016\/j.scienta.2022.110909","article-title":"Underutilized Citrus Species: An Insight of Their Nutraceutical Potential and Importance for the Development of Functional Food","volume":"296","author":"Kumar","year":"2022","journal-title":"Sci. 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