{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:01:11Z","timestamp":1771660871120,"version":"3.50.1"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia through FEDER (European Fund for Regional Development)-COMPETE-QREN-EU","award":["UID\/FIS\/04650\/2013"],"award-info":[{"award-number":["UID\/FIS\/04650\/2013"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia through FEDER (European Fund for Regional Development)-COMPETE-QREN-EU","award":["UID\/FIS\/04650\/2019"],"award-info":[{"award-number":["UID\/FIS\/04650\/2019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>This work explores the self-assembly and optical properties of a novel chiral, aromatic-rich Boc-Phe-Phe dipeptide derivative functionalized with a benzothiazole bicyclic ring that forms supramolecular structures. Leveraging the well-known self-assembling capabilities of diphenylalanine dipeptides, this modified derivative introduces a heterocyclic benzothiazole unit that significantly enhances the fluorescence of the resulting nanostructures. The derivative\u2019s rich aromatic character drives the formation of supramolecular structures through self-organization mechanisms influenced by quantum confinement. By adjusting the solvent system, the nanostructures exhibit tunable morphologies, ranging from nanospheres to nanobelts. The nonlinear optical properties of these self-assembled structures were studied and an estimated deff of ~0.9 pm\/V was obtained, which is comparable to that reported for the highly aromatic triphenylalanine peptide.<\/jats:p>","DOI":"10.3390\/molecules30040942","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T08:36:19Z","timestamp":1739867779000},"page":"942","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Novel Benzothiazole Boc-Phe-Phe-Bz Derivative Dipeptide Forming Fluorescent and Nonlinear Optical Self-Assembled Structures"],"prefix":"10.3390","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5380-9212","authenticated-orcid":false,"given":"Rosa M. F.","family":"Baptista","sequence":"first","affiliation":[{"name":"Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9133-9812","authenticated-orcid":false,"given":"Daniela","family":"Santos","sequence":"additional","affiliation":[{"name":"Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0892-5975","authenticated-orcid":false,"given":"N. F.","family":"Cunha","sequence":"additional","affiliation":[{"name":"Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0732-1774","authenticated-orcid":false,"given":"Maria Cid\u00e1lia R.","family":"Castro","sequence":"additional","affiliation":[{"name":"Institute for Polymers and Composites, University of Minho, Campus de Azur\u00e9m, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0397-8808","authenticated-orcid":false,"given":"Pedro V.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Institute for Polymers and Composites, University of Minho, Campus de Azur\u00e9m, 4800-058 Guimar\u00e3es, Portugal"}]},{"given":"Ana V.","family":"Machado","sequence":"additional","affiliation":[{"name":"Institute for Polymers and Composites, University of Minho, Campus de Azur\u00e9m, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7968-5038","authenticated-orcid":false,"given":"Michael S.","family":"Belsley","sequence":"additional","affiliation":[{"name":"Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0862-1683","authenticated-orcid":false,"given":"Etelvina","family":"de Matos Gomes","sequence":"additional","affiliation":[{"name":"Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Zheng, Y., Mao, K., Chen, S., and Zhu, H. 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