{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:44:23Z","timestamp":1768970663485,"version":"3.49.0"},"reference-count":49,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T00:00:00Z","timestamp":1576800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011596","name":"Conselleria d'Educaci\u00f3, Investigaci\u00f3, Cultura i Esport","doi-asserted-by":"publisher","award":["APOSTD\/2018\/228"],"award-info":[{"award-number":["APOSTD\/2018\/228"]}],"id":[{"id":"10.13039\/501100011596","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["IJCI-2015-26432"],"award-info":[{"award-number":["IJCI-2015-26432"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["Project MAT2016-78437-R"],"award-info":[{"award-number":["Project MAT2016-78437-R"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["Project MAT2017-88123-P"],"award-info":[{"award-number":["Project MAT2017-88123-P"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>Poly(lactic acid) (PLA) is one of the most commonly employed synthetic biopolymers for facing plastic waste problems. Despite its numerous strengths, its inherent brittleness, low toughness, and thermal stability, as well as a relatively slow crystallization rate represent some limiting properties when packaging is its final intended application. In the present work, silver nanoparticles obtained from a facile and green synthesis method, mediated with chitosan as a reducing and stabilizing agent, have been introduced in the oligomeric lactic acid (OLA) plasticized PLA in order to obtain nanocomposites with enhanced properties to find potential application as antibacterial food packaging materials. In this way, the green character of the matrix and plasticizer was preserved by using an eco-friendly synthesis protocol of the nanofiller. The X-ray diffraction (XRD) and differential scanning calorimetry (DSC) results proved the modification of the crystalline structure as well as the crystallinity of the pristine matrix when chitosan mediated silver nanoparticles (AgCH-NPs) were present. The final effect over the thermal stability, mechanical properties, degradation under composting conditions, and antimicrobial behavior when AgCH-NPs were added to the neat plasticized PLA matrix was also investigated. The obtained results revealed interesting properties of the final nanocomposites to be applied as materials for the targeted application.<\/jats:p>","DOI":"10.3390\/nano10010022","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T09:50:33Z","timestamp":1576835433000},"page":"22","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Multifunctional PLA Blends Containing Chitosan Mediated Silver Nanoparticles: Thermal, Mechanical, Antibacterial, and Degradation Properties"],"prefix":"10.3390","volume":"10","author":[{"given":"Agueda","family":"Sonseca","sequence":"first","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"},{"name":"Instituto de Tecnolog\u00eda de Materiales, Universitat Polit\u00e8cnica de Val\u00e8ncia (UPV), Camino de Vera s\/n, 46022 Valencia, Spain"}]},{"given":"Salim","family":"Madani","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Biochemistry, University Ferhat Abbas, Setif 19000, Algeria"}]},{"given":"Gema","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]},{"given":"V\u00edctor","family":"Hevilla","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0734-766X","authenticated-orcid":false,"given":"Coro","family":"Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2061-0351","authenticated-orcid":false,"given":"Marta","family":"Fern\u00e1ndez-Garc\u00eda","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0210-1246","authenticated-orcid":false,"given":"Alexandra","family":"Mu\u00f1oz-Bonilla","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6730-578X","authenticated-orcid":false,"given":"Noureddine","family":"Charef","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Biochemistry, University Ferhat Abbas, Setif 19000, Algeria"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6386-5798","authenticated-orcid":false,"given":"Daniel","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"MacroEng Group, Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros, ICTP-CSIC, C\/ Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Plataform for \u201cSustainable Plastics towards a Circular Economy\u201d (SUSPLAST-CSIC), 28006 Madrid, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.polymdegradstab.2004.07.016","article-title":"Dependence of biodegradability of plastics in compost on the shape of specimens","volume":"87","author":"Yang","year":"2005","journal-title":"Polym. Degrad. Stab."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1021\/bm000046k","article-title":"Selective enzymatic degradations of poly(L-lactide) and poly(\u2208-caprolactone) blend films","volume":"1","author":"Liu","year":"2000","journal-title":"Biomacromolecules"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1023\/A:1020200822435","article-title":"A Literature Review of Poly(Lactic Acid)","volume":"9","author":"Garlotta","year":"2001","journal-title":"J. Polym. Environ."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.progpolymsci.2009.12.003","article-title":"Poly(lactic acid) modifications","volume":"35","author":"Rasal","year":"2010","journal-title":"Prog. Polym. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.carbon.2013.06.080","article-title":"Structure, gas-barrier properties and overall migration of poly(lactic acid) films coated with hydrogenated amorphous carbon layers","volume":"63","author":"Mattioli","year":"2013","journal-title":"Carbon N. Y."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.lwt.2008.02.015","article-title":"Tensile, water vapor barrier and antimicrobial properties of PLA\/nanoclay composite films","volume":"42","author":"Rhim","year":"2009","journal-title":"LWT\u2014Food Sci. Technol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1002\/(SICI)1097-4628(19980118)67:3<405::AID-APP3>3.0.CO;2-Q","article-title":"Blends of aliphatic polyesters. II. Hydrolysis of solution-cast blends from poly(L-lactide) and poly(\u0395-caprolactone) in phosphate-buffered solution","volume":"67","author":"Tsuji","year":"1998","journal-title":"J. Appl. Polym. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.polymdegradstab.2009.07.001","article-title":"Biodegradation of poly(lactic acid) and its nanocomposites","volume":"94","author":"Fukushima","year":"2009","journal-title":"Polym. Degrad. Stab."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/1521-379X(200108)53:8<356::AID-STAR356>3.0.CO;2-7","article-title":"Physical and mechanical properties of biobased materials\u2014Starch, polylactate and polyhydroxybutyrate","volume":"53","author":"Petersen","year":"2001","journal-title":"Starch\/Staerke"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1002\/macp.1996.021970427","article-title":"Modification of poly(L-lactides) by blending: Mechanical and hydrolytic behavior","volume":"197","author":"Varpomaa","year":"1996","journal-title":"Macromol. Chem. Phys."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"39870","DOI":"10.1039\/C6RA07667J","article-title":"Preparation and characterization of interface-modified PLA\/starch\/PCL ternary blends using PLLA\/triclosan antibacterial nanoparticles for medical applications","volume":"6","author":"Davoodi","year":"2016","journal-title":"RSC Adv."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.colsurfa.2016.05.007","article-title":"Study on the effects of non-solvent and nanoparticle concentrations on surface properties of water-repellent biocompatible l-lactide\/glycolide\/trimethylene carbonate terpolymers","volume":"502","author":"Khakbaz","year":"2016","journal-title":"Colloids Surfaces A Physicochem. Eng. Asp."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1002\/app.21779","article-title":"Mechanical properties of biodegradable composites from poly lactic acid (PLA) and microcrystalline cellulose (MCC)","volume":"97","author":"Mathew","year":"2005","journal-title":"J. Appl. Polym. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.carbpol.2016.08.037","article-title":"Interface modified polylactic acid\/starch\/poly \u03b5-caprolactone antibacterial nanocomposite blends for medical applications","volume":"155","author":"Davachi","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"ref_15","first-page":"7","article-title":"Intelligent food packaging\u2014Research and development","volume":"11","author":"Cierpiszewski","year":"2015","journal-title":"LogForum"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/02652030701744538","article-title":"Applications and implications of nanotechnologies for the food sector","volume":"25","author":"Chaudhry","year":"2008","journal-title":"Food Addit. Contam. Part A Chem. Anal. Control. Expo. Risk Assess."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"374","DOI":"10.3390\/challe5020374","article-title":"Advances in Packaging Methods, Processes and Systems","volume":"5","author":"Mahalik","year":"2014","journal-title":"Challenges"},{"key":"ref_18","first-page":"711","article-title":"Recent advances in potential nanoparticles and nanotechnology for sensing food-bome pathogens and their toxins in foods and crops: Current technologies and limitations","volume":"26","author":"Koedrith","year":"2014","journal-title":"Sensors Mater."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"16292","DOI":"10.3390\/s131216292","article-title":"Aptamer-based analysis: A promising alternative for food safety control","volume":"13","year":"2013","journal-title":"Sensors"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0924-2244(99)00032-1","article-title":"Developments in the active packaging of foods","volume":"10","author":"Vermeiren","year":"1999","journal-title":"Trends Food Sci. Technol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/0142-9612(94)90028-0","article-title":"Biocompatibility of silver-coated polyurethane catheters and silvercoated Dacron\u00ae material","volume":"15","author":"Oloffs","year":"1994","journal-title":"Biomaterials"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.eurpolymj.2015.01.030","article-title":"The roadmap of antimicrobial polymeric materials in macromolecular nanotechnology","volume":"65","year":"2015","journal-title":"Eur. Polym. J."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"\u00c1lvarez-Paino, M., Mu\u00f1oz-Bonilla, A., and Fern\u00e1ndez-Garc\u00eda, M. (2017). Antimicrobial polymers in the nano-world. Nanomaterials, 7.","DOI":"10.3390\/nano7020048"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Mu\u00f1oz-Bonilla, A., Echeverria, C., Sonseca, \u00c1., Arrieta, M.P., and Fern\u00e1ndez-Garc\u00eda, M. (2019). Bio-based polymers with antimicrobial properties towards sustainable development. Materials, 12.","DOI":"10.3390\/ma12040641"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0309-1740(02)00121-3","article-title":"Antimicrobial food packaging in meat industry","volume":"62","author":"Quintavalla","year":"2002","journal-title":"Meat Sci."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Chowdhury, N.R., Cowin, A.J., Zilm, P., and Vasilev, K. (2018). \u201cChocolate\u201d gold nanoparticles\u2014one pot synthesis and biocompatibility. Nanomaterials, 8.","DOI":"10.3390\/nano8070496"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.reactfunctpolym.2018.08.006","article-title":"Plasma induced cytocompatibility of stabilized poly-L-lactic acid doped with graphene nanoplatelets","volume":"131","author":"Pinkner","year":"2018","journal-title":"React. Funct. Polym."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Murugadoss, A., and Chattopadhyay, A. (2008). A \u201cgreen\u201d chitosan-silver nanoparticle composite as a heterogeneous as well as micro-heterogeneous catalyst. Nanotechnology, 19.","DOI":"10.1088\/0957-4484\/19\/01\/015603"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ijfoodmicro.2008.03.004","article-title":"The antibacterial properties of a novel chitosan-Ag-nanoparticle composite","volume":"124","author":"Sanpui","year":"2008","journal-title":"Int. J. Food Microbiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.carbpol.2013.11.040","article-title":"Preparation, characterization and cytotoxicity of schizophyllan\/silver nanoparticle composite","volume":"102","author":"Fouda","year":"2014","journal-title":"Carbohydr. Polym."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.carbpol.2012.03.022","article-title":"Green synthesis of hyaluronan fibers with silver nanoparticles","volume":"89","author":"Hrdina","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s10924-011-0378-1","article-title":"A novel method for the preparation of silver\/chitosan-O-methoxy polyethylene glycol core shell nanoparticles","volume":"20","author":"Aly","year":"2012","journal-title":"J. Polym. Environ."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.flm.2018.04.002","article-title":"Synthesis of chitosan mediated silver nanoparticles (Ag NPs) for potential antimicrobial applications","volume":"2","author":"Kalaivani","year":"2018","journal-title":"Front. Lab. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s13204-012-0180-y","article-title":"A novel green one-step synthesis of silver nanoparticles using chitosan: Catalytic activity and antimicrobial studies","volume":"4","author":"Venkatesham","year":"2014","journal-title":"Appl. Nanosci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.carres.2009.09.001","article-title":"The synthesis of chitosan-based silver nanoparticles and their antibacterial activity","volume":"344","author":"Wei","year":"2009","journal-title":"Carbohydr. Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1007\/BF01498927","article-title":"Investigation of the structure of solution grown crystals of lactide copolymers by means of chemical reactions","volume":"251","author":"Fischer","year":"1973","journal-title":"Kolloid-Zeitschrift Zeitschrift F\u00fcr Polym."},{"key":"ref_37","unstructured":"(2019, December 18). ASTM International, ASTM E2149: Standard Test Method for Determining the Antimicrobial Activity of Antimicrobial Agents Under Dynamic Contact Conditions. Available online: https:\/\/www.astm.org\/Standards\/E2149.html."},{"key":"ref_38","unstructured":"(2019, December 18). International Standard, ISO20200:2015: Determination of the degree of disintegration of plastic materials under simulated composting conditions in a laboratory-scale test: International Standard. Available online: https:\/\/www.iso.org\/standard\/63367.html."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Chu, Z., Zhao, T., Li, L., Fan, J., and Qin, Y. (2017). Characterization of antimicrobial poly (lactic acid)\/nano-composite films with silver and zinc oxide nanoparticles. Materials, 10.","DOI":"10.3390\/ma10060659"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"8385","DOI":"10.1021\/ma0348674","article-title":"Helix distortion and crystal structure of the \u03b1-form of poly(L-lactide)","volume":"36","author":"Sasaki","year":"2003","journal-title":"Macromolecules"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1002\/pc.24217","article-title":"Enhancement of crystallinity and toughness of poly (L-lactic acid) influenced by Ag nanoparticles processed by twin screw extruder","volume":"39","author":"Sanchez","year":"2018","journal-title":"Polym. Compos."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"6898","DOI":"10.1021\/ma071258d","article-title":"Polymorphous crystallization and multiple melting behavior of poly(L-lactide): Molecular weight dependence","volume":"40","author":"Pan","year":"2007","journal-title":"Macromolecules"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"4003","DOI":"10.1016\/S0032-3861(96)00987-1","article-title":"Morphology of poly(L-lactide) solution-grown crystals","volume":"38","author":"Miyata","year":"1997","journal-title":"Polymer (Guildf)"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1163\/092050609X12524778957011","article-title":"Physicochemical and biological properties of nano-hydroxyapatite-reinforced aliphatic polyurethanes membranes","volume":"21","author":"Liu","year":"2010","journal-title":"J. Biomater. Sci. Polym. Ed."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.polymdegradstab.2015.09.002","article-title":"Biodegradable nanocomposites based on poly(ester-urethane) and nanosized hydroxyapatite: Plastificant and reinforcement effects","volume":"121","author":"Arrieta","year":"2015","journal-title":"Polym. Degrad. Stab."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"827028","DOI":"10.1155\/2014\/827028","article-title":"Effects of Inorganic Fillers on the Thermal and Mechanical Properties of Poly(lactic acid)","volume":"2014","author":"Liu","year":"2014","journal-title":"Int. J. Polym. Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0141-3910(00)00152-X","article-title":"Enzymatic degradation of polylactide stereocopolymers with predominant D-lactyl contents","volume":"71","author":"Li","year":"2000","journal-title":"Polym. Degrad. Stab."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0142-9612(97)00226-3","article-title":"Further investigations on the hydrolytic degradation of poly (DL-lactide)","volume":"20","author":"Li","year":"1999","journal-title":"Biomaterials"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1002\/1097-4628(20001220)78:13<2369::AID-APP140>3.0.CO;2-N","article-title":"Py-GC\/MS an effective technique to characterizing of degradation mechanism of poly (L-lactide) in the different environment","volume":"78","author":"Khabbaz","year":"2000","journal-title":"J. Appl. Polym. Sci."}],"container-title":["Nanomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-4991\/10\/1\/22\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:43:58Z","timestamp":1760190238000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-4991\/10\/1\/22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,20]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1]]}},"alternative-id":["nano10010022"],"URL":"https:\/\/doi.org\/10.3390\/nano10010022","relation":{},"ISSN":["2079-4991"],"issn-type":[{"value":"2079-4991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,20]]}}}