{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T05:58:57Z","timestamp":1776837537447,"version":"3.51.2"},"reference-count":50,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T00:00:00Z","timestamp":1592784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010198","name":"Ministerio de Econom\u00eda, Industria y Competitividad, Gobierno de Espa\u00f1a","doi-asserted-by":"publisher","award":["MAT2016-78437-R"],"award-info":[{"award-number":["MAT2016-78437-R"]}],"id":[{"id":"10.13039\/501100010198","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["SP2020\/70"],"award-info":[{"award-number":["SP2020\/70"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>The preparation of hybrid polymeric systems based on carbon derivatives with a cationic polymer is described. The polymer used is a copolymer of a quaternizable methacrylic monomer with another dopamine-based monomer capable of anchoring to carbon compounds. Graphene oxide and graphene as well as hybrid polymeric systems were widely characterized by infrared, Raman and photoemission X-ray spectroscopies, electron scanning microscopy, zeta potential and thermal degradation. These allowed confirming the attachment of copolymer onto carbonaceous materials. Besides, the antimicrobial activity of hybrid polymeric systems was tested against Gram positive Staphylococcus aureus and Staphylococcus epidermidis and Gram negative Escherichia coli and Pseudomonas aeruginosa bacteria. The results showed the antibacterial character of these hybrid systems.<\/jats:p>","DOI":"10.3390\/nano10061218","type":"journal-article","created":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T06:11:02Z","timestamp":1592892662000},"page":"1218","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Antibacterial Character of Cationic Polymers Attached to Carbon-Based Nanomaterials"],"prefix":"10.3390","volume":"10","author":[{"given":"Daniela","family":"Plach\u00e1","sequence":"first","affiliation":[{"name":"Nanotechnology Centre, V\u0160B\u2013Technical University of Ostrava, 17. listopadu 2172\/15, 708 00 Ostrava-Poruba, Czech Republic"},{"name":"Centre ENET, V\u0160B\u2013Technical University of Ostrava, 17. listopadu 2172\/15, 708 00 Ostrava-Poruba, Czech Republic"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0210-1246","authenticated-orcid":false,"given":"Alexandra","family":"Mu\u00f1oz-Bonilla","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros (ICTP-CSIC), C\/Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Platform for Sustainable Plastics towards a Circular Economy-Spanish National Research Council (SusPlast-CSIC), 28006 Madrid, Spain"}]},{"given":"Kate\u0159ina","family":"\u0160krlov\u00e1","sequence":"additional","affiliation":[{"name":"Nanotechnology Centre, V\u0160B\u2013Technical University of Ostrava, 17. listopadu 2172\/15, 708 00 Ostrava-Poruba, Czech Republic"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0734-766X","authenticated-orcid":false,"given":"Coro","family":"Echeverria","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros (ICTP-CSIC), C\/Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Platform for Sustainable Plastics towards a Circular Economy-Spanish National Research Council (SusPlast-CSIC), 28006 Madrid, Spain"}]},{"given":"Alberto","family":"Chiloeches","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros (ICTP-CSIC), C\/Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Platform for Sustainable Plastics towards a Circular Economy-Spanish National Research Council (SusPlast-CSIC), 28006 Madrid, Spain"}]},{"given":"Martin","family":"Petr","sequence":"additional","affiliation":[{"name":"Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palack\u00fd University Olomouc, 17. listopadu 1192\/12, 771 46 Olomouc, Czech Republic"}]},{"given":"Khalid","family":"Lafdi","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Construction Engineering, Northumbria University, Newcastle upon Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2061-0351","authenticated-orcid":false,"given":"Marta","family":"Fern\u00e1ndez-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda de Pol\u00edmeros (ICTP-CSIC), C\/Juan de la Cierva 3, 28006 Madrid, Spain"},{"name":"Interdisciplinary Platform for Sustainable Plastics towards a Circular Economy-Spanish National Research Council (SusPlast-CSIC), 28006 Madrid, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4165","DOI":"10.1002\/smll.201601841","article-title":"The antibacterial applications of graphene and its derivatives","volume":"12","author":"Shi","year":"2016","journal-title":"Small"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"6776","DOI":"10.1039\/C7TA00009J","article-title":"Graphene-based antimicrobial polymeric membranes: A review","volume":"5","author":"Zhu","year":"2017","journal-title":"J. Mater. Chem. A"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1021\/jacs.5b11411","article-title":"Mechanisms of the antimicrobial activities of graphene materials","volume":"138","author":"Zou","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1039\/C2NR32092D","article-title":"Mussel-inspired functionalization of graphene for synthesizing ag-polydopamine-graphenenanosheets as antibacterial materials","volume":"5","author":"Zhang","year":"2013","journal-title":"Nanoscale"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1021\/am200536p","article-title":"Covalent binding of single-walled carbon nanotubes to polyamide membranes for antimicrobial surface properties","volume":"3","author":"Tiraferri","year":"2011","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"8892","DOI":"10.1039\/c1cc11877c","article-title":"Antimicrobial graphene polymer (pvk-go) nanocomposite films","volume":"47","author":"Santos","year":"2011","journal-title":"Chem. Commun. (Camb.)"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/mame.201100334","article-title":"Bactericidal and anticorrosion properties in pvk\/mwnt nanocomposite coatings on stainless steel","volume":"297","author":"Santos","year":"2012","journal-title":"Macromol. Mater. Eng."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/macp.201200464","article-title":"Temperature-responsiveness and antimicrobial properties of cnt-pnipam hybrid brush films","volume":"214","author":"Pangilinan","year":"2013","journal-title":"Macromol. Chem. Phys."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jcis.2012.08.025","article-title":"Carbon nanotube-based antimicrobial biomaterials formed via layer-by-layer assembly with polypeptides","volume":"388","author":"Aslan","year":"2012","journal-title":"J. Colloid Interface Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"4746","DOI":"10.1039\/c2nr30774j","article-title":"Toxicity of a polymer-graphene oxide composite against bacterial planktonic cells, biofilms, and mammalian cells","volume":"4","author":"Santos","year":"2012","journal-title":"Nanoscale"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.carbon.2016.04.046","article-title":"The controversial antibacterial activity of graphene-based materials","volume":"105","author":"Hegab","year":"2016","journal-title":"Carbon"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Placha, D., and Jampilek, J. (2019). Graphenic materials for biomedical applications. Nanomaterials, 9.","DOI":"10.3390\/nano9121758"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"8458","DOI":"10.1021\/acsnano.5b03368","article-title":"Graphene induces formation of pores that kill spherical and rod-shaped bacteria","volume":"9","author":"Pham","year":"2015","journal-title":"ACS Nano"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"5156","DOI":"10.1016\/j.carbon.2012.06.056","article-title":"Synthesis and antifungal activity of reduced graphene oxide nanosheets","volume":"50","author":"Sawangphruk","year":"2012","journal-title":"Carbon"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"6279","DOI":"10.1021\/jp200686k","article-title":"Wrapping bacteria by graphene nanosheets for isolation from environment, reactivation by sonication, and inactivation by near-infrared irradiation","volume":"115","author":"Akhavan","year":"2011","journal-title":"J. Phys. Chem. B"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e00547-18","DOI":"10.1128\/AAC.00547-18","article-title":"Antimicrobial and antibiofilm efficacy of graphene oxide against chronic wound microorganisms","volume":"62","author":"Zappacosta","year":"2018","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1039\/C6EN00427J","article-title":"Antibacterial property of graphene oxide: The role of phototransformation","volume":"4","author":"Hou","year":"2017","journal-title":"Environ. Sci. Nano"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.3389\/fmicb.2019.02995","article-title":"Graphene oxide mediated broad-spectrum antibacterial based on bimodal action of photodynamic and photothermal effects","volume":"10","author":"Romero","year":"2019","journal-title":"Front. Microbiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jnoncrysol.2011.11.007","article-title":"Facile preparation of graphene-based chitosan films: Enhanced thermal, mechanical and antibacterial properties","volume":"358","author":"Lim","year":"2012","journal-title":"J. Non Cryst. Solids"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/nnano.2009.58","article-title":"Chemical methods for the production of graphenes","volume":"4","author":"Park","year":"2009","journal-title":"Nat. Nanotechnol."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Kumar, P., Huo, P., Zhang, R., and Liu, B. (2019). Antibacterial properties of graphene-based nanomaterials. Nanomaterials, 9.","DOI":"10.3390\/nano9050737"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1039\/C5BM00058K","article-title":"Graphene film doped with silver nanoparticles: Self-assembly formation, structural characterizations, antibacterial ability, and biocompatibility","volume":"3","author":"Zhang","year":"2015","journal-title":"Biomater. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"8542","DOI":"10.1021\/am5022914","article-title":"Graphene-based nanocomposite as an effective, multifunctional, and recyclable antibacterial agent","volume":"6","author":"Tian","year":"2014","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Cobos, M., De-La-Pinta, I., Quindos, G., Fernandez, M.J., and Fernandez, M.D. (2020). Graphene oxide-silver nanoparticle nanohybrids: Synthesis, characterization, and antimicrobial properties. Nanomaterials, 10.","DOI":"10.3390\/nano10020376"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"17617","DOI":"10.1021\/acsami.8b03185","article-title":"Highly stable graphene-based nanocomposite (GO-PEI-Ag) with broad-spectrum, long-term antimicrobial activity and antibiofilm effects","volume":"10","author":"Zhao","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.colsurfa.2018.12.024","article-title":"Visible active reduced graphene oxide loaded titania for photodecomposition of ciprofloxacin and its antibacterial activity","volume":"564","author":"Raja","year":"2019","journal-title":"Colloids Surf. Physicochem. Eng. Asp."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Hsueh, Y.H., Hsieh, C.T., Chiu, S.T., Tsai, P.H., Liu, C.Y., and Ke, W.J. (2019). Antibacterial property of composites of reduced graphene oxide with nano-silver and zinc oxide nanoparticles synthesized using a microwave-assisted approach. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20215394"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jsamd.2018.02.002","article-title":"Versatile graphene oxide decorated by star shaped zinc oxide nanocomposites with superior adsorption capacity and antimicrobial activity","volume":"3","author":"Archana","year":"2018","journal-title":"J. Sci. Adv. Mater. Devices"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"6616","DOI":"10.1039\/C7TB00722A","article-title":"Designing polymeric adhesives for antimicrobial materials: Poly(ethylene imine) polymer, graphene, graphene oxide and molybdenum trioxide - a biomimetic approach","volume":"5","author":"Nguyen","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.apsusc.2014.02.099","article-title":"Flexible bactericidal graphene oxide\u2013chitosan layers for stem cell proliferation","volume":"301","author":"Mazaheri","year":"2014","journal-title":"Appl. Surf. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s41038-018-0115-2","article-title":"Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergistic antibacterial activity to promote infected wound healing","volume":"6","author":"Liu","year":"2018","journal-title":"Burn. Trauma"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.colsurfb.2016.01.046","article-title":"Click synthesis of quaternized poly(dimethylaminoethyl methacrylate) functionalized graphene oxide with improved antibacterial and antifouling ability","volume":"141","author":"Tu","year":"2016","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"105272","DOI":"10.1016\/j.porgcoat.2019.105272","article-title":"Adhesive antibacterial coatings based on copolymers bearing thiazolium cationic groups and catechol moieties as robust anchors","volume":"136","author":"Chiloeches","year":"2019","journal-title":"Prog. Org. Coat."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1021\/ja01539a017","article-title":"Preparation of graphitic oxide","volume":"80","author":"Hummers","year":"1958","journal-title":"J. Am. Chem. Soc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"36969","DOI":"10.1039\/C5RA04558D","article-title":"Optimization of graphene-based materials outperforming host epoxy matrices","volume":"5","author":"Guadagno","year":"2015","journal-title":"RSC Adv."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1039\/c3tc31124d","article-title":"Raman spectroscopy for the study of reduction mechanisms and optimization of conductivity in graphene oxide thin films","volume":"1","author":"Botas","year":"2013","journal-title":"J. Mater. Chem. C"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"247","DOI":"10.5714\/CL.2013.14.4.247","article-title":"Layer-by-layer assembled graphene oxide films and barrier properties of thermally reduced graphene oxide membranes","volume":"14","author":"Kim","year":"2013","journal-title":"Carbon Lett."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0038-1098(81)90686-4","article-title":"Observation of raman band shifting with excitation wavelength for carbons and graphites","volume":"39","author":"Vidano","year":"1981","journal-title":"Solid State Commun."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/smll.200901173","article-title":"Probing layer number and stacking order of few-layer graphene by raman spectroscopy","volume":"6","author":"Hao","year":"2010","journal-title":"Small"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.physrep.2009.02.003","article-title":"Raman spectroscopy in graphene","volume":"473","author":"Malard","year":"2009","journal-title":"Phys. Rep."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Chiloeches, A., Echeverr\u00eda, C., Fern\u00e1ndez-Garc\u00eda, M., and Mu\u00f1oz-Bonilla, A. (2019). Influence of polymer composition and substrate on the performance of bioinspired coatings with antibacterial activity. Coatings, 9.","DOI":"10.3390\/coatings9110733"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"63058","DOI":"10.1039\/C6RA10903A","article-title":"Graphene material prepared by thermal reduction of the electrochemically synthesized graphite oxide","volume":"6","author":"Florczak","year":"2016","journal-title":"RSC Adv."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"8270","DOI":"10.1039\/C5PY01358E","article-title":"One-step grafting of polymers to graphene oxide","volume":"6","author":"Thomas","year":"2015","journal-title":"Polym. Chem."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"17315","DOI":"10.1021\/ja205168x","article-title":"Dual path mechanism in the thermal reduction of graphene oxide","volume":"133","author":"Larciprete","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.progpolymsci.2012.06.004","article-title":"Catechols as versatile platforms in polymer chemistry","volume":"38","author":"Faure","year":"2013","journal-title":"Prog. Polym. Sci."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1021\/am201664n","article-title":"Reduction and functionalization of graphene oxide sheets using biomimetic dopamine derivatives in one step","volume":"4","author":"Kaminska","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"15802","DOI":"10.1021\/ja808001a","article-title":"Solutions of negatively charged graphene sheets and ribbons","volume":"130","author":"Drummond","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1039\/C3CC49325C","article-title":"Positively charged graphene oxide nanoparticle: Precisely label the plasma membrane of live cell and sensitively monitor extracellular ph in situ","volume":"50","author":"Zhu","year":"2014","journal-title":"Chem. Commun. (Camb.)"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"11059","DOI":"10.1039\/c3cc46457a","article-title":"Water can stably disperse liquid-exfoliated graphene","volume":"49","author":"Yi","year":"2013","journal-title":"Chem. Commun. (Camb.)"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3449","DOI":"10.1039\/C5PY00288E","article-title":"Antimicrobial polymethacrylates based on quaternized 1,3-thiazole and 1,2,3-triazole side-chain groups","volume":"6","author":"Tejero","year":"2015","journal-title":"Polym. 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