{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:55:12Z","timestamp":1774353312092,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2018,11,11]],"date-time":"2018-11-11T00:00:00Z","timestamp":1541894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FEDER through the Operational Programme Competitiveness and Internationalization","award":["POCI-01-0145-FEDER-016829"],"award-info":[{"award-number":["POCI-01-0145-FEDER-016829"]}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["FCT PTDC\/DTP-EPI\/6506\/2014"],"award-info":[{"award-number":["FCT PTDC\/DTP-EPI\/6506\/2014"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"FCT and the POPH\/FSE Program","award":["PD\/BD\/105824\/2014"],"award-info":[{"award-number":["PD\/BD\/105824\/2014"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The role of vitamin D on pulmonary function is unclear and is mostly studied in patients, smokers and elderly people. The aim of this paper was to evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] concentration and pulmonary function in young adults. Cross-sectional analysis of 499 individuals that were evaluated at 21 years of age as part of the population-based cohort Epidemiological Health Investigation of Teenagers in Porto (EPITeen). Serum 25(OH)D was categorized according to the Institute of Medicine. Pulmonary function was evaluated using spirometry. Linear regression models were used to estimate the regression coefficients (\u03b2) and its 95% confidence intervals (95% CI), and were adjusted for confounders. Education, smoking, body mass index, and season of evaluation were determinants of serum 25(OH)D concentration. Prevalence of serum 25(OH)D concentration &lt;50 nmol\/L was 48.9%. A decrease in all pulmonary function parameters, with the decrease of serum 25(OH)D, was observed. The higher effect was found for peak expiratory flow (PEF). Having as reference participants with serum 25(OH)D concentration \u226550 nmol\/L, PEF was significantly lower for those with a concentration of 30 to &lt;50 nmol\/L (\u03b2= \u22120.576; 95% CI: \u22120.943, \u22120.210), and for those with a concentration of &lt;30 nmol\/L (\u03b2= \u22120.650; 95% CI: \u22121.155, \u22120.146). Although only PEF attained statistical significance, the consistent results with the other parameters support the role of serum 25(OH)D to promote better pulmonary function in young adults.<\/jats:p>","DOI":"10.3390\/nu10111728","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T02:42:41Z","timestamp":1542163361000},"page":"1728","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association of Serum 25-Hydroxyvitamin D Concentration with Pulmonary Function in Young Adults"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2661-0283","authenticated-orcid":false,"given":"Vanda","family":"Craveiro","sequence":"first","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00ba 135, 4050-600 Porto, Portugal"}]},{"given":"Maria","family":"Cabral","sequence":"additional","affiliation":[{"name":"Unidade de Epidemiologia\u2014Departamento de Ci\u00eancias da Sa\u00fade P\u00fablica e Forenses e Educa\u00e7\u00e3o M\u00e9dica da Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9649-3177","authenticated-orcid":false,"given":"Joana","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00ba 135, 4050-600 Porto, Portugal"}]},{"given":"Helena","family":"Falc\u00e3o","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Imunoalergologia do Centro Hospitalar do Porto, E.P.E., 4099-001 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4836-6311","authenticated-orcid":false,"given":"Jo\u00e3o Tiago","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00ba 135, 4050-600 Porto, Portugal"},{"name":"Servi\u00e7o de Patologia Cl\u00ednica do Centro Hospitalar de S\u00e3o Jo\u00e3o, E.P.E., 4200-319 Porto, Portugal"},{"name":"Departamento de Biomedicina da Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal"}]},{"given":"Elisabete","family":"Ramos","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00ba 135, 4050-600 Porto, Portugal"},{"name":"Unidade de Epidemiologia\u2014Departamento de Ci\u00eancias da Sa\u00fade P\u00fablica e Forenses e Educa\u00e7\u00e3o M\u00e9dica da Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,11]]},"reference":[{"key":"ref_1","unstructured":"Institute of Medicine (2011). 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