{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T17:08:19Z","timestamp":1773248899449,"version":"3.50.1"},"reference-count":25,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T00:00:00Z","timestamp":1648339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Portuguese Society for Endocrinology, Diabetes &amp; Metabolism","award":["Bolsa Dra. Maria da Concei\u00e7\u00e3o Barbas \/ SPEDM \u2013 2016"],"award-info":[{"award-number":["Bolsa Dra. Maria da Concei\u00e7\u00e3o Barbas \/ SPEDM \u2013 2016"]}]},{"name":"Portuguese Foundation for Science and Technology","award":["UIDB\/00709\/2020"],"award-info":[{"award-number":["UIDB\/00709\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Iodine deficiency is a common problem in pregnant women and may have implications for maternal and child health. Iodine supplementation during pregnancy has been recommended by several scientific societies. We undertook a cross-sectional survey to assess the efficacy of these recommendations in a European iodine-deficient region. Urinary iodine concentrations (UIC) were determined in pregnant women before (n = 203) and after (n = 136) the implementation of guidelines for iodine supplementation in pregnancy. Iodine supplementation (200 \u03bcg\/day) reduced the proportion of pregnant women with severe iodine deficiency (37.4% to 18.0%, p = 0.0002). The median UIC increased from 67.6 \u00b5g\/L to 106.8 \u00b5g\/L but remained below the recommended target level (&gt;150 \u00b5g\/L) for pregnant women. In conclusion, iodine supplementation in pregnant women improved iodine status in this iodine-deficient region but was insufficient to achieve recommended iodine levels in pregnancy. Additional measures, such as the adjustment of the dose or timing of supplementation, or universal salt iodization, may be needed.<\/jats:p>","DOI":"10.3390\/nu14071393","type":"journal-article","created":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T21:29:36Z","timestamp":1648416576000},"page":"1393","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Iodine Supplementation in Pregnancy in an Iodine-Deficient Region: A Cross-Sectional Survey"],"prefix":"10.3390","volume":"14","author":[{"given":"Carla A.","family":"Lopes","sequence":"first","affiliation":[{"name":"CICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilh\u00e3, Portugal"},{"name":"Departamento da Sa\u00fade da Crian\u00e7a e da Mulher, Centro Hospitalar Universit\u00e1rio Cova da Beira, 6200-251 Covilh\u00e3, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8653-1122","authenticated-orcid":false,"given":"Susana","family":"Prazeres","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Endocrinologia, Servi\u00e7o de Patologia Cl\u00ednica, Instituto Portugu\u00eas de Oncologia de Lisboa Francisco Gentil, 1099-023 Lisboa, Portugal"}]},{"given":"Jos\u00e9","family":"Martinez-de-Oliveira","sequence":"additional","affiliation":[{"name":"CICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilh\u00e3, Portugal"},{"name":"Departamento da Sa\u00fade da Crian\u00e7a e da Mulher, Centro Hospitalar Universit\u00e1rio Cova da Beira, 6200-251 Covilh\u00e3, Portugal"}]},{"given":"Edward","family":"Limbert","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Endocrinologia, Instituto Portugu\u00eas de Oncologia de Lisboa Francisco Gentil, 1099-023 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9326-8900","authenticated-orcid":false,"given":"Manuel C.","family":"Lemos","sequence":"additional","affiliation":[{"name":"CICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilh\u00e3, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Jouanne, M., Oddoux, S., Noel, A., and Voisin-Chiret, A.S. 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