{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T17:18:32Z","timestamp":1776878312843,"version":"3.51.2"},"reference-count":66,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T00:00:00Z","timestamp":1652313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UI\/05704\/2020"],"award-info":[{"award-number":["UI\/05704\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["2021.07673.BD"],"award-info":[{"award-number":["2021.07673.BD"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UI\/05704\/2020"],"award-info":[{"award-number":["UI\/05704\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["2021.07673.BD"],"award-info":[{"award-number":["2021.07673.BD"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The oral glucose tolerance test (OGTT) is recommended for assessing abnormalities in glucose homeostasis. Recognised as the gold standard test for diagnosing diabetes, the OGTT provides useful information about glucose tolerance. However, it does not replicate the process of absorption and digestion of complex foods, such as that which occurs with a mixed meal tolerance test (MMTT), an alternative that is still not well explored in the diagnosis of metabolic alterations. The MMTT could be an asset in detecting glucose homeostasis disorders, including diabetes since it has more similarities to the common dietary pattern, allowing early detection of subtle changes in metabolic homeostasis in response to combined nutrients. This alternative has the advantage of being more tolerable and pleasant to patients since it induces a more gradual increase in blood glucose, thus reducing the risk of rebound hypoglycemia and other related complications. The present article reviewed the clinical data available regarding the possibility of screening or diagnosing altered glucose homeostasis, including type 2 diabetes mellitus, with the MMTT.<\/jats:p>","DOI":"10.3390\/nu14102032","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T21:46:53Z","timestamp":1652392013000},"page":"2032","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Metabolic Effects of an Oral Glucose Tolerance Test Compared to the Mixed Meal Tolerance Tests: A Narrative Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Marlene","family":"Lages","sequence":"first","affiliation":[{"name":"ciTechCare\u2014Center for Innovative Care and Health Technology, Polytechnic of Leiria, 2410-541 Leiria, Portugal"},{"name":"Faculty of Nutrition and Food Science, University of Porto, 4150-180 Porto, Portugal"},{"name":"EPIUnit\u2014Instituto de Saude Publica, Universidade do Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3043-1720","authenticated-orcid":false,"given":"Renata","family":"Barros","sequence":"additional","affiliation":[{"name":"Faculty of Nutrition and Food Science, University of Porto, 4150-180 Porto, Portugal"},{"name":"EPIUnit\u2014Instituto de Saude Publica, Universidade do Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7035-7799","authenticated-orcid":false,"given":"Pedro","family":"Moreira","sequence":"additional","affiliation":[{"name":"Faculty of Nutrition and Food Science, University of Porto, 4150-180 Porto, Portugal"},{"name":"EPIUnit\u2014Instituto de Saude Publica, Universidade do Porto, 4200-450 Porto, Portugal"},{"name":"Laboratorio Para a Investiga\u00e7\u00e3o Integrativa e Translacional em Saude Populacional (ITR), Portugal Centre in Physical Activity, Health and Leisure, University of Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6079-1105","authenticated-orcid":false,"given":"Maria P.","family":"Guarino","sequence":"additional","affiliation":[{"name":"Faculty of Nutrition and Food Science, University of Porto, 4150-180 Porto, Portugal"},{"name":"School of Health Sciences, Polytechnic of Leiria, 2411-901 Leiria, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2014). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 37, S81\u2013S90.","DOI":"10.2337\/dc14-S081"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nrendo.2017.151","article-title":"Global aetiology and epidemiology of type 2 diabetes mellitus and its complications","volume":"14","author":"Zheng","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_3","unstructured":"International Diabetes Federation (2019). IDF Diabetes Atlas, International Diabetes Federation. [9th ed.]."},{"key":"ref_4","first-page":"19","article-title":"Diabetes: Factos e N\u00fameros 2016, 2017 e 2018","volume":"15","author":"Raposo","year":"2020","journal-title":"Rev. Port. Diabetes"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","article-title":"Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1001\/jama.287.19.2570","article-title":"Diabetes and atherosclerosis epidemiology, pathophysiology, and management","volume":"287","author":"Beckman","year":"2002","journal-title":"J. Am. Med. Assoc."},{"key":"ref_7","unstructured":"World Health Organization, and International Diabetes Federation (2006). Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia: Report of a WHO\/IDF Consultation, World Health Organization. Available online: http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/43588\/9241594934_eng.pdf?sequence=1."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2337\/diacare.26.2.385","article-title":"Gestational diabetes mellitus: Is a diagnosis associated with an increase in maternal anxiety and stress in the short and intermediate term?","volume":"26","author":"Daniells","year":"2003","journal-title":"Diabetes Care"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"766","DOI":"10.7326\/0003-4819-148-10-200805200-00009","article-title":"Screening for gestational diabetes mellitus: A systematic review for the U.S. preventive services task force","volume":"148","author":"Hillier","year":"2008","journal-title":"Ann. Intern. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.diabres.2011.09.002","article-title":"Postprandial metabolic responses to mixed versus liquid meal tests in healthy men and men with type 2 diabetes","volume":"94","author":"Brodovicz","year":"2011","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/07315724.1985.10720086","article-title":"Plasma glucose and insulin profiles in normal subjects ingesting diets of varying carbohydrate, fat, and protein content","volume":"4","author":"Nuttall","year":"1982","journal-title":"J. Am. Coll. Nutr."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.2337\/diacare.7.5.465","article-title":"Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load","volume":"7","author":"Nuttall","year":"1984","journal-title":"Diabetes Care"},{"key":"ref_13","first-page":"7","article-title":"Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes","volume":"51","year":"2002","journal-title":"Diabetes"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1463-1326.2008.00922.x","article-title":"Excess glycaemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: Is the OGTT a valid predictor of postprandial hyperglycaemia and vice versa?","volume":"11","author":"Meier","year":"2009","journal-title":"Diabetes Obes. Metab."},{"key":"ref_15","first-page":"11","article-title":"HbA1c as a Marker of Prediabetes: A Reliable Screening Tool or Not","volume":"1","author":"Sequeira","year":"2017","journal-title":"Insights Nutr. Metab."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"i6538","DOI":"10.1136\/bmj.i6538","article-title":"Efficacy and Effectiveness of Screen and Treat Policies in Prevention of Type 2 Diabetes: Systematic Review and Meta-Analysis of Screening Tests and Interventions","volume":"356","author":"Barry","year":"2017","journal-title":"BMJ"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2147\/DMSO.S100074","article-title":"Novel Biomarkers for Prediabetes, Diabetes, and Associated Complications","volume":"10","author":"Dorcely","year":"2017","journal-title":"Diabetes Metab. Syndr. Obes. Targets Ther."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40842-019-0080-0","article-title":"Global Epidemiology of Prediabetes\u2014Present and Future Perspectives","volume":"5","author":"Hostalek","year":"2019","journal-title":"Clin. Diabetes Endocrinol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.flm.2017.06.002","article-title":"Accuracy of fasting plasma glucose and hemoglobin A1c testing for the early detection of diabetes: A pilot study","volume":"1","author":"Chung","year":"2017","journal-title":"Front. Lab. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"R105","DOI":"10.1530\/JOE-13-0616","article-title":"Nutrient Regulation of Insulin Secretion and Action","volume":"221","author":"Newsholme","year":"2014","journal-title":"J. Endocrinol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.2337\/diab.33.12.1150","article-title":"Demonstration of a Dawn Phenomenon in Normal Human Volunteers","volume":"33","author":"Bolli","year":"1984","journal-title":"Diabetes"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1001\/jama.284.24.3157","article-title":"Diurnal Variation in Fasting Plasma Glucose: Implications for Diagnosis of Diabetes in Patients Examined in the Afternoon","volume":"284","author":"Troisi","year":"2000","journal-title":"JAMA"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4093\/dmj.2013.37.5.349","article-title":"Prevalence of Diabetes and Prediabetes according to Fasting Plasma Glucose and HbA1c","volume":"37","author":"Jeon","year":"2013","journal-title":"Diabetes Metab. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2337\/diacare.23.2.181","article-title":"Prevalence of Undiagnosed Diabetes in Three American Indian Populations. A Comparison of the 1997 American Diabetes Association Diagnostic Criteria and the 1985 World Health Organization Diagnostic Criteria: The Strong Heart Study","volume":"23","author":"Lee","year":"2000","journal-title":"Diabetes Care"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.5144\/0256-4947.2004.183","article-title":"Diagnostic Accuracy of the American Diabetes Association Criteria in the Diagnosis of Glucose Intolerance among High-Risk Omani Subjects","volume":"24","author":"Charles","year":"2004","journal-title":"Ann. Saudi Med."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"(2022). American Diabetes Association Professionals Committee Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes\u20142022. Diabetes Care, 45, S17\u2013S38.","DOI":"10.2337\/dc22-S002"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/dme.14181","article-title":"Impact of Mismatches in HbA1c vs Glucose Values on the Diagnostic Classification of Diabetes and Prediabetes","volume":"37","author":"Gonzalez","year":"2020","journal-title":"Diabet. Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2174\/1573399811309010025","article-title":"Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes","volume":"9","author":"Fu","year":"2012","journal-title":"Curr. Diabetes Rev."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.tem.2008.07.006","article-title":"The Islet \u03b2-Cell: Fuel Responsive and Vulnerable","volume":"19","author":"Nolan","year":"2008","journal-title":"Trends Endocrinol. Metab."},{"key":"ref_30","first-page":"35","article-title":"Nutritional Regulation of Insulin Secretion: Implications for Diabetes","volume":"33","author":"Newsholme","year":"2012","journal-title":"Clin. Biochem. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.2337\/diacare.26.5.1485","article-title":"Association of Hypoglycemia and Cardiac Ischemia","volume":"26","author":"Desouza","year":"2003","journal-title":"Diabetes Care"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0168-8227(97)00108-3","article-title":"An IDDM Patient Who Complained of Chest Oppression with Ischemic Changes on ECG in Insulin-Induced Hypoglycemia","volume":"39","author":"Miura","year":"1998","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/s41574-020-0357-5","article-title":"International Consensus on the Diagnosis and Management of Dumping Syndrome","volume":"16","author":"Scarpellini","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0016-5085(95)90382-8","article-title":"Mechanism of Accelerated Gastric Emptying of Liquids and Hyperglycemia in Patients with Type II Diabetes Mellitus","volume":"109","author":"Frank","year":"1995","journal-title":"Gastroenterology"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3389\/fendo.2019.00144","article-title":"Impact of Nutrient Type and Sequence on Glucose Tolerance: Physiological Insights and Therapeutic Implications","volume":"10","author":"Nesti","year":"2019","journal-title":"Front. Endocrinol."},{"key":"ref_36","unstructured":"Evans, J.D. (1996). Straightforward Statistics for the Behavioral Sciences, Brooks\/Cole Publishing."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.amjms.2017.08.007","article-title":"Using Ice Cream for Diagnosis of Diabetes Mellitus and Impaired Glucose Tolerance: An Alternative to the Oral Glucose Tolerance Test","volume":"354","author":"Chanprasertpinyo","year":"2017","journal-title":"Am. J. Med. Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"336","DOI":"10.2337\/diacare.21.3.336","article-title":"Variation of Postprandial Plasma Glucose, Palatability, and Symptoms Associated with a Standardized Mixed Test Meal versus 75 g Oral Glucose","volume":"21","author":"Wolever","year":"1998","journal-title":"Diabetes Care"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF00572826","article-title":"Comparison of the Metabolic Effects of Mixed Meal and Standard Oral Glucose Tolerance Test on Glucose, Insulin and C-Peptide Response in Healthy, Impaired Glucose Tolerance, Mild and Severe Non-Insulin-Dependent Diabetic Subjects","volume":"29","author":"Marena","year":"1992","journal-title":"Acta Diabetol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1507\/endocrj.53.173","article-title":"Development of Cookie Test for the Simultaneous Determination of Glucose Intolerance, Hyperinsulinemia, Insulin Resistance and Postprandial Dyslipidemia","volume":"53","author":"Harano","year":"2006","journal-title":"Endocr. J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/gme.0b013e318221bfc9","article-title":"The \u201cMuffin Test\u201d\u2014An Alternative to the Oral Glucose Tolerance Test for Detecting Impaired Glucose Tolerance","volume":"19","author":"Traub","year":"2012","journal-title":"Menopause"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"810","DOI":"10.4158\/EP09330.OR","article-title":"Assessing Impaired Glucose Tolerance and Insulin Resistance in Polycystic Ovarian Syndrome with A Muffin Test: An Alternative to the Glucose Tolerance Test","volume":"16","author":"Freeman","year":"2010","journal-title":"Endocr. Pract."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"e13301","DOI":"10.1111\/ctr.13301","article-title":"Comparison of Metabolic Responses to the Mixed Meal Tolerance Test vs the Oral Glucose Tolerance Test after Successful Clinical Islet Transplantation","volume":"32","author":"Forbes","year":"2018","journal-title":"Clin. Transplant."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/ijgo.12427","article-title":"Randomized Cross-Over Trial Comparing the Diagnosis of Gestational Diabetes by Oral Glucose Tolerance Test and a Designed Breakfast Glucose Profile","volume":"141","author":"Marais","year":"2018","journal-title":"Int. J. Gynecol. Obstet."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"522.e1","DOI":"10.1016\/j.ajog.2014.11.010","article-title":"Candy Twists as an Alternative to the Glucola Beverage in Gestational Diabetes Mellitus Screening","volume":"212","author":"Racusin","year":"2015","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_46","first-page":"18","article-title":"A Standardised Breakfast Tolerance Test in Pregnancy: Comparison with the 75 g Oral Glucose Tolerance Test in Unselected Mothers and in Those with Impaired Glucose Tolerance","volume":"66","author":"Roberts","year":"1997","journal-title":"Ulster Med. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0002-9378(87)80272-7","article-title":"The \u201cBreakfast Tolerance Test\u201d: Screening for Gestational Diabetes with a Standardized Mixed Nutrient Meal","volume":"157","author":"Coustan","year":"1987","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2008). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 31, S55\u2013S60.","DOI":"10.2337\/dc08-S055"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0002-9378(82)90349-0","article-title":"Criteria for Screening Tests for Gestational Diabetes","volume":"144","author":"Carpenter","year":"1982","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ijgo.2006.10.004","article-title":"Breakfast as a Screening Test for Gestational Diabetes","volume":"96","author":"Eslamian","year":"2006","journal-title":"Int. J. Gynecol. Obstet."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.2337\/diab.28.12.1039","article-title":"Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance","volume":"28","author":"Group","year":"1979","journal-title":"Diabetes"},{"key":"ref_52","unstructured":"World Health Organization (1980). WHO Expert Committee on Diabetes Mellitus: Second Report, World Health Organization. Available online: https:\/\/apps.who.int\/iris\/handle\/10665\/41399."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2337\/diab.40.2.S8","article-title":"Diabetic Pregnancy Study Group of the European Association for the Study of Diabetes Influence of Pregnancy on the 75-g OGTT: A Prospective Multicenter Study","volume":"40","author":"Lind","year":"1991","journal-title":"Diabetes"},{"key":"ref_54","first-page":"118","article-title":"Screening for Gestational Diabetes: Examining a Breakfast Meal Test","volume":"29","author":"Marais","year":"2016","journal-title":"S. Afr. J. Clin. Nutr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.2337\/diabetes.54.7.2212","article-title":"Erythromycin Antagonizes the Deceleration of Gastric emptying by Glucagon-Like Peptide 1 and Unmasks Its Insulinotropic Effect in Heathy Subjects","volume":"54","author":"Meier","year":"2005","journal-title":"Diabetes"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1210\/jc.2003-030049","article-title":"Normalization of Glucose Concentrations and Deceleration of Gastric Emptying after Solid Meals during Intravenous Glucagon-Like Peptide 1 in Patients with Type 2 Diabetes","volume":"88","author":"Meier","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF00265086","article-title":"Gastric and Oesophageal Emptying in Patients with Type 2 (Non-Insulin-Dependent) Diabetes Mellitus","volume":"32","author":"Horowitz","year":"1989","journal-title":"Diabetologia"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.metabol.2009.07.039","article-title":"Effects of Meal Size and Composition on Incretin, \u03b1-Cell, and \u03b2-Cell Responses","volume":"59","author":"Rijkelijkhuizen","year":"2010","journal-title":"Metabolism."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1210\/jc.2005-2644","article-title":"Effects of Fat on Gastric Emptying of and the Glycemic, Insulin, and Incretin Responses to a Carbohydrate Meal in Type 2 Diabetes","volume":"91","author":"Gentilcore","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Martens, M.J.I., Lemmens, S.G.T., Born, J.M., and Westerterp-Plantenga, M.S. (2012). Satiating Capacity and Post-Prandial Relationships between Appetite Parameters and Gut-Peptide Concentrations with Solid and Liquefied Carbohydrate. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0042110"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1111\/dme.14292","article-title":"Barriers to Completing Oral Glucose Tolerance Testing in Women at Risk of Gestational Diabetes","volume":"37","author":"Lachmann","year":"2020","journal-title":"Diabet. Med."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Frid, A.H., Nilsson, M., Holst, J.J., and Bj\u00f6rck, I.M. (2022, March 02). Effect of Whey on Blood Glucose and Insulin Responses to Composite Breakfast and Lunch Meals in Type 2 Diabetic Subjects 1\u20133. Available online: https:\/\/academic.oup.com\/ajcn\/article-abstract\/82\/1\/69\/4863431.","DOI":"10.1093\/ajcn.82.1.69"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"E779","DOI":"10.1152\/ajpendo.90233.2008","article-title":"Incretin and islet hormonal responses to fat and protein ingestion in healthy men","volume":"295","author":"Carr","year":"2008","journal-title":"Am. J. Physiol.-Endocrinol. Metab."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2706","DOI":"10.1210\/jc.2002-021873","article-title":"Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus","volume":"88","author":"Krarup","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/sj.ejcn.1602953","article-title":"Meal composition affects insulin secretion in women with type 2 diabetes: A comparison with healthy controls. The Hoorn prandial study","volume":"63","author":"Alssema","year":"2009","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"e14798","DOI":"10.1111\/dme.14798","article-title":"Are All Glucose Solutions Used for oGTT Equal?","volume":"39","author":"Heinemann","year":"2022","journal-title":"Diabet. 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