{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T01:43:43Z","timestamp":1773107023980,"version":"3.50.1"},"reference-count":49,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Consejer\u00eda de Econom\u00eda, Innovaci\u00f3n y Ciencia","award":["B-CTS-100-UGR-20"],"award-info":[{"award-number":["B-CTS-100-UGR-20"]}]},{"name":"Consejer\u00eda de Econom\u00eda, Innovaci\u00f3n y Ciencia","award":["PPJIA2021-03"],"award-info":[{"award-number":["PPJIA2021-03"]}]},{"name":"Consejer\u00eda de Econom\u00eda, Innovaci\u00f3n y Ciencia","award":["FPU20\/05674"],"award-info":[{"award-number":["FPU20\/05674"]}]},{"name":"University of Granada","award":["B-CTS-100-UGR-20"],"award-info":[{"award-number":["B-CTS-100-UGR-20"]}]},{"name":"University of Granada","award":["PPJIA2021-03"],"award-info":[{"award-number":["PPJIA2021-03"]}]},{"name":"University of Granada","award":["FPU20\/05674"],"award-info":[{"award-number":["FPU20\/05674"]}]},{"DOI":"10.13039\/501100020636","name":"Spanish Ministry of Education and Vocational Training","doi-asserted-by":"publisher","award":["B-CTS-100-UGR-20"],"award-info":[{"award-number":["B-CTS-100-UGR-20"]}],"id":[{"id":"10.13039\/501100020636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020636","name":"Spanish Ministry of Education and Vocational Training","doi-asserted-by":"publisher","award":["PPJIA2021-03"],"award-info":[{"award-number":["PPJIA2021-03"]}],"id":[{"id":"10.13039\/501100020636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020636","name":"Spanish Ministry of Education and Vocational Training","doi-asserted-by":"publisher","award":["FPU20\/05674"],"award-info":[{"award-number":["FPU20\/05674"]}],"id":[{"id":"10.13039\/501100020636","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Objectives: To analyze the effects of the combination of Extra Virgin Olive Oil (EVOO) supplementation and a health-related lifestyle intervention on disease activity and cardiovascular disease risk factors in Systemic Lupus Erythematosus (SLE). Methods: A total of 38 women with SLE were randomly assigned to EVOO (n = 9) and EVOO combined with multicomponent health promotion and physical exercise program (EVOO + HRLI) (n = 15) or control (CG) (n = 14) groups for 24 weeks. Baseline and post-intervention assessments were performed, collecting data on disease activity, accrual damage, blood biochemical parameters, arterial stiffness parameters, Framingham risk score, anthropometric and body composition measurements, and cardiovascular risk factors. Results: No changes in disease activity were observed in any group after the intervention. For cardiovascular risk, significant differences were observed in the intervention groups for systolic and mean blood pressure, with greater reductions in the EVOO + HRLI (p = 0.036 vs. p &lt; 0.001; p = 0.017 vs. p &lt; 0.001, respectively). The EVOO group showed significant reductions in BFM and BFP (p = 0.042, p = 0.022, respectively). The EVOO+ HRLI group also showed significant reductions in triglycerides (p &lt; 0.001), Aix brachial (p = 0.037), central systolic blood pressure (p &lt; 0.001), central pulse pressure (p = 0.05), body mass index (p = 0.006), body fat mass and skeletal muscle mass (p = 0.039) after the intervention. Conclusions: Our findings suggest that a multidisciplinary program integrating nutritional interventions, health education, and the promotion of regular physical activity in SLE patients has the potential to significantly improve cardiovascular risk factors and body composition parameters. Thus, integrating this approach into clinical practice alongside usual pharmacological treatments would be beneficial for SLE patients. Clinical Trial Registration: NCT05261529.<\/jats:p>","DOI":"10.3390\/nu17061076","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T10:38:48Z","timestamp":1742380728000},"page":"1076","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["EFINUTRILES Study: Integrative Extra Virgin Olive Oil and Multimodal Lifestyle Interventions for Cardiovascular Health and SLE Management"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7479-1835","authenticated-orcid":false,"given":"Roc\u00edo","family":"Gil-Guti\u00e9rrez","sequence":"first","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain"},{"name":"CTS-436 Group, University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Sport and Health University Research Institute (iMUDS), University of Granada, 18007 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-0032","authenticated-orcid":false,"given":"Irene","family":"Medina-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"University of Granada, 18016 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5299-0710","authenticated-orcid":false,"given":"Miguel","family":"Quesada-Caballero","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Centro de Salud Albayda La Cruz, Calle Virgen de la Consolaci\u00f3n, 12, Distrito Sanitario Granada-Metropolitano, Servicio Andaluz de Salud, 18015 Granada, Spain"}]},{"given":"Francisco Javier","family":"de la Hera-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Systemic Autoimmune Diseases Unit, Hospital Universitario San Cecilio, 18016 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1789-4226","authenticated-orcid":false,"given":"M\u00f3nica","family":"Zamora-Pasadas","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Systemic Autoimmune Diseases Unit, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3834-1711","authenticated-orcid":false,"given":"Irene","family":"Cantarero-Villanueva","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Sport and Health University Research Institute (iMUDS), University of Granada, 18007 Granada, Spain"},{"name":"Department of Physical Therapy, University of Granada, 18016 Granada, Spain"},{"name":"BIO-277 Group, University of Granada, 18016 Granada, Spain"}]},{"given":"Luis","family":"Albend\u00edn-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"},{"name":"Caser\u00eda de Montijo Health Center, Granda-Metropolitan Health District, Andalusian Health Service, Calle Virgen de la Consolaci\u00f3n, 12, 18015 Granda, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0050-5004","authenticated-orcid":false,"given":"V\u00edtor","family":"Parola","sequence":"additional","affiliation":[{"name":"Health Sciences Research Unit: Nursing (UICISA:E), Nursing School of Coimbra (ESEnfC), 3000 Coimbra, Portugal"},{"name":"Portugal Centre for Evidence-Based Practice: A Joanna Briggs Institute Centre of Excellence (PCEBP), 3000 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0263-7000","authenticated-orcid":false,"given":"Blanca","family":"Rueda-Medina","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9165-4349","authenticated-orcid":false,"given":"Mar\u00eda","family":"Correa-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain"},{"name":"CTS-436 Group, University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria (ibs.GRANADA), 18014 Granada, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"ref_1","unstructured":"Justiz Vaillant, A.A., Goyal, A., and Varacallo, M. (2023, April 14). Systemic Lupus Erythematosus. StatPearls [Internet], Available online: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535405\/."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1016\/S0140-6736(24)00398-2","article-title":"Systemic lupus erythematosus","volume":"403","author":"Hoy","year":"2024","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.medcli.2020.05.009","article-title":"Lupus eritematoso sist\u00e9mico 2020","volume":"155","year":"2020","journal-title":"Med. Clin."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.atherosclerosis.2020.01.028","article-title":"Endothelial dysfunction and arterial stiffness in patients with systemic lupus erythematosus: A systematic review and meta-analysis","volume":"297","year":"2020","journal-title":"Atherosclerosis"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1177\/0961203318790676","article-title":"Incidence of cardiovascular risk factors in female patients with systemic lupus erythematosus: A 3-year follow-up cohort","volume":"27","author":"Martins","year":"2018","journal-title":"Lupus"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1496462","DOI":"10.1155\/2020\/1496462","article-title":"Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function","volume":"2020","author":"Man","year":"2020","journal-title":"Oxid. Med. Cell Longev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/rheumatology\/keaa210","article-title":"Beneficial effect of Mediterranean diet on disease activity and cardiovascular risk in systemic lupus erythematosus patients: A cross-sectional study","volume":"60","year":"2021","journal-title":"Rheumatology"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Jimenez-Lopez, C., Carpena, M., Louren\u00e7o-Lopes, C., Gallardo-Gomez, M., Lorenzo, J.M., Barba, F.J., Prieto, M.A., and Simal-Gandara, J. (2020). Bioactive Compounds and Quality of Extra Virgin Olive Oil. Foods, 9.","DOI":"10.3390\/foods9081014"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Gavil\u00e1n-Carrera, B., Ruiz-Cobo, A., Amaro-Gahete, F.J., Soriano-Maldonado, A., and Vargas-Hitos, J.A. (2023). No Changes in Body Composition and Adherence to the Mediterranean Diet after a 12-Week Aerobic Training Intervention in Women with Systemic Lupus Erythematosus: The EJERCITA-LES Study. Nutrients, 15.","DOI":"10.3390\/nu15204424"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1080\/09638288.2020.1808904","article-title":"Effects of 12-week aerobic exercise on patient-reported outcomes in women with systemic lupus erythematosus","volume":"44","author":"Sabio","year":"2022","journal-title":"Disabil. Rehabil."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1002\/ptr.5662","article-title":"Dry Olive Leaf Extract in Combination with Methotrexate Reduces Cell Damage in Early Rheumatoid Arthritis Patients-A Pilot Study","volume":"30","author":"Borozan","year":"2016","journal-title":"Phytother. Res."},{"key":"ref_12","first-page":"537","article-title":"Study of the Effect of an Oral Formulation of Fig and Olive on Rheumatoid Arthritis (RA) Remission Indicators: A Randomized Clinical Trial","volume":"15","author":"Bahadori","year":"2016","journal-title":"Iran. J. Pharm. Res."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Frade, S., O\u2019Neill, S., Greene, D., Nutter, E., and Cameron, M. (2023). Exercise as adjunctive therapy for systemic lupus erythematosus. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD014816.pub2"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Zhang, L., Luan, W., Geng, S., Ye, S., Wang, X., Qian, L., Ding, Y., Li, T., and Jiang, A. (2019). Lack of patient education is risk factor of disease flare in patients with systemic lupus erythematosus in China. BMC Health Serv. Res., 19.","DOI":"10.1186\/s12913-019-4206-y"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"100796","DOI":"10.1016\/j.jaim.2023.100796","article-title":"Integrative approach to lifestyle management: Implications for public health research & practice in the context of SDG-3-","volume":"14","author":"Jayanna","year":"2023","journal-title":"J. Ayurveda Integr. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11882-020-00978-6","article-title":"Investigating Health Literacy in Systemic Lupus Erythematosus: A Descriptive Review","volume":"20","author":"Maheswaranathan","year":"2020","journal-title":"Curr. Allergy Asthma Rep."},{"key":"ref_17","first-page":"1080","article-title":"The phenolic fraction of extra virgin olive oil modulates the activation and the inflammatory response of T cells from patients with systemic lupus erythematosus and healthy donors","volume":"61","author":"Lucena","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e004171","DOI":"10.1136\/rmdopen-2024-004171","article-title":"Recommendations for physical activity and exercise in persons living with Systemic Lupus Erythematosus (SLE): Consensus by an international task force","volume":"10","author":"Blaess","year":"2024","journal-title":"RMD Open"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1038\/sj.ejcn.1602004","article-title":"Development of a short dietary intake questionnaire for the quantitative estimation of adherence to a cardioprotective Mediterranean diet","volume":"58","author":"Wright","year":"2004","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"107747","DOI":"10.1016\/j.cct.2024.107747","article-title":"Effects of an intervention with EVOO and physical exercise in systemic lupus erythematosus patients: Efinutriles trial protocol","volume":"148","year":"2025","journal-title":"Contemp. Clin. Trials"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1249\/01.MSS.0000078924.61453.FB","article-title":"International physical activity questionnaire: 12-country reliability and validity","volume":"35","author":"Craig","year":"2003","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.jhsa.2006.06.014","article-title":"Hand span influences optimal grip span in male and female teenagers","volume":"31","author":"Ruiz","year":"2006","journal-title":"J. Hand Surg. Am."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/14397595.2020.1775928","article-title":"Which is the best SLE activity index for clinical trials?","volume":"31","author":"Ohmura","year":"2021","journal-title":"Mod. Rheumatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/art.1780400506","article-title":"The reliability of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology Damage Index in patients with systemic lupus erythematosus","volume":"40","author":"Gladman","year":"1997","journal-title":"Arthritis Rheum."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/HJH.0b013e3282f314f7","article-title":"A new oscillometric method for assessment of arterial stiffness: Comparison with tonometric and piezo-electronic methods","volume":"26","author":"Baulmann","year":"2008","journal-title":"J. Hypertens."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1001\/archinte.165.22.2644","article-title":"Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus","volume":"165","author":"Wannamethee","year":"2005","journal-title":"Arch. Intern. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"246","DOI":"10.4162\/nrp.2012.6.3.246","article-title":"The framingham risk score, diet, and inflammatory markers in Korean men with metabolic syndrome","volume":"6","author":"Sohn","year":"2012","journal-title":"Nutr. Res. Pract."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1161\/01.CIR.97.18.1837","article-title":"Prediction of coronary heart disease using risk factor categories","volume":"97","author":"Wilson","year":"1998","journal-title":"Circulation"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1177\/0961203319841435","article-title":"Non-pharmacologic therapies for systemic lupus erythematosus","volume":"28","author":"Fangtham","year":"2019","journal-title":"Lupus"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Islam, M.A., Khandker, S.S., Kotyla, P.J., and Hassan, R. (2020). Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review. Front. Immunol., 11.","DOI":"10.3389\/fimmu.2020.01477"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/acr.23925","article-title":"Dietary Omega Polyunsaturated Fatty Acid Intake and Patient-Reported Outcomes in Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program","volume":"72","author":"Charoenwoodhipong","year":"2020","journal-title":"Arthritis Care Res."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"152128","DOI":"10.1016\/j.semarthrit.2022.152128","article-title":"Benefits & risks of physical activity in patients with Systemic Lupus Erythematosus: A systematic review of the literature","volume":"58","author":"Blaess","year":"2023","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"124","DOI":"10.31138\/mjr.32.2.124","article-title":"The Relationship of Lifestyle with Disease Activity among Patients with Systemic Lupus Erythematosus: A Descriptive-Correlational Study","volume":"32","author":"Sayadi","year":"2021","journal-title":"Mediterr. J. Rheumatol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jshs.2024.02.002","article-title":"The anti-inflammatory effects of exercise on autoimmune diseases: A 20-year systematic review","volume":"13","author":"Luo","year":"2024","journal-title":"J. Sport. Health Sci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.atherosclerosis.2006.12.028","article-title":"Carotid intima-media thickness is inversely associated with olive oil consumption","volume":"196","author":"Irimia","year":"2008","journal-title":"Atherosclerosis"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Casas, R., Sacanella, E., Urpi-Sarda, M., Chiva-Blanch, G., Ros, E., Martinez-Gonzalez, M.A., Covas, M.I., Rosa Ma Lamuela-Raventos Salas-Salvado, J., Fiol, M., and Aros, F. (2014). The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease. A randomized trial. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0100084"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.atherosclerosis.2017.12.012","article-title":"Mediterranean diet improves endothelial function in patients with diabetes and prediabetes: A report from the CORDIOPREV study","volume":"269","author":"Camargo","year":"2018","journal-title":"Atherosclerosis"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Toledo, E., Hu, F.B., Estruch, R., Buil-Cosiales, P., Corella, D., Salas-Salvad\u00f3, J., Covas, M.I., Ar\u00f3s, F., G\u00f3mez-Gracia, E., and Fiol, M. (2013). Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: Results from a randomized controlled trial. BMC Med., 11.","DOI":"10.1186\/1741-7015-11-207"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"36","DOI":"10.2174\/1871530317666171114114321","article-title":"Anti-inflammatory Activity of Extra Virgin Olive Oil Polyphenols: Which Role in the Prevention and Treatment of Immune-Mediated Inflammatory Diseases?","volume":"18","author":"Santangelo","year":"2018","journal-title":"Endocr. Metab. Immune Disord. Drug Targets"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2147\/ITT.S377076","article-title":"Managing Cardiovascular Risk in Systemic Lupus Erythematosus: Considerations for the Clinician","volume":"12","author":"Semalulu","year":"2023","journal-title":"Immunotargets Ther."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Soriano-Maldonado, A., Morillas-de-Laguno, P., Sabio, J.M., Gavil\u00e1n-Carrera, B., Rosales-Castillo, A., Montalb\u00e1n-M\u00e9ndez, C., S\u00e1ez-Ur\u00e1n, L.M., Callejas-Rubio, J.L., and Vargas-Hitos, J.A. (2018). Effects of 12-week Aerobic Exercise on Arterial Stiffness, Inflammation, and Cardiorespiratory Fitness in Women with Systemic LUPUS Erythematosus: Non-Randomized Controlled Trial. J. Clin. Med., 7.","DOI":"10.3390\/jcm7120477"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.medcli.2024.04.023","article-title":"Associations of physical activity, sedentary time, and fitness with cardiovascular risk and atherosclerosis over 3 years in women with systemic lupus erythematosus","volume":"163","year":"2024","journal-title":"Med. Clin."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1007\/s10067-019-04701-3","article-title":"Altered body composition and increased visceral adipose tissue in premenopausal and late postmenopausal patients with SLE","volume":"38","author":"Li","year":"2019","journal-title":"Clin. Rheumatol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/gerona\/glx227","article-title":"Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms","volume":"73","author":"Tosti","year":"2018","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Tsigalou, C., Konstantinidis, T., Paraschaki, A., Stavropoulou, E., Voidarou, C., and Bezirtzoglou, E. (2020). Mediterranean Diet as a Tool to Combat Inflammation and Chronic Diseases. An Overview. Biomedicines, 8.","DOI":"10.3390\/biomedicines8070201"},{"key":"ref_46","first-page":"659","article-title":"Waist-Hip Ratio More Appropriate Than Body Mass Index","volume":"117","author":"Haufs","year":"2020","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_47","first-page":"19","article-title":"Relaci\u00f3n del \u00cdndice Cintura-Estatura (ICE) con Circunferencia Cintura e \u00cdndice de Cintura Cadera como predictor para obesidad y riesgo metab\u00f3lico en adolescentes de secundaria","volume":"19","author":"Gallegos","year":"2020","journal-title":"RESPYN Rev. P\u00fablica Nutr."},{"key":"ref_48","first-page":"1","article-title":"Utilidad del \u00edndice cintura\/cadera en la detecci\u00f3n del riesgo cardiometab\u00f3lico en individuos sobrepesos y obesos","volume":"2","year":"2018","journal-title":"Rev. Cubana Endocrinol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"37","DOI":"10.15280\/jlm.2022.12.1.37","article-title":"Lifestyle Interventions and Weight Management in Systemic Lupus Erythematosus Patients: A Systematic Literature Review and Metanalysis","volume":"12","author":"Goessler","year":"2022","journal-title":"J. Lifestyle Med."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/6\/1076\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:56:42Z","timestamp":1760029002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/17\/6\/1076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,19]]},"references-count":49,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["nu17061076"],"URL":"https:\/\/doi.org\/10.3390\/nu17061076","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,19]]}}}