{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:46:48Z","timestamp":1760147208797,"version":"build-2065373602"},"reference-count":32,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T00:00:00Z","timestamp":1673913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Global Health and Tropical Medicine Center","award":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"],"award-info":[{"award-number":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"]}]},{"name":"FCT","award":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"],"award-info":[{"award-number":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"]}]},{"name":"Interdisciplinary Research Center on Animal Health","award":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"],"award-info":[{"award-number":["UID\/Multi\/04413\/2013","UIDB\/00276\/2020","LA\/P\/0059\/2020-AL4AnimalS","CIISA-INOV 4\/2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>In September 2021, Bagaza virus (BAGV), a member of the Ntaya group from the Flavivirus genus, was detected for the first time in Portugal, in the heart and the brain of a red-legged partridge found dead in a hunting ground in Serpa (Alentejo region; southern Portugal). Here we report the genomic characterization of the full-length sequence of the BAGV detected (BAGV\/PT\/2021), including phylogenetic reconstructions and spaciotemporal analyses. Phylogenies inferred from nucleotide sequence alignments, complemented with the analysis of amino acid alignments, indicated that the BAGV strain from Portugal is closely related to BAGV strains previously detected in Spain, suggesting a common ancestor that seems to have arrived in the Iberia Peninsula in the late 1990s to early 2000s. In addition, our findings support previous observations that BAGV and Israel turkey meningoencephalitis virus (ITV) belong to the same viral species.<\/jats:p>","DOI":"10.3390\/pathogens12020150","type":"journal-article","created":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T01:41:20Z","timestamp":1673919680000},"page":"150","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Genome Characterization and Spaciotemporal Dispersal Analysis of Bagaza Virus Detected in Portugal, 2021"],"prefix":"10.3390","volume":"12","author":[{"given":"Marta","family":"Falc\u00e3o","sequence":"first","affiliation":[{"name":"Institute of Hygiene and Tropical Medicine (IHMT), NOVA University of Lisbon, Rua da Junqueira 100, 1349-008 Lisbon, Portugal"}]},{"given":"Margarida","family":"Barros","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas, NMS|FCM, NOVA Medical School, Universidade Nova de Lisboa, Campo dos M\u00e1rtires da P\u00e1tria 130, 1169-056 Lisbon, Portugal"}]},{"given":"Margarida D.","family":"Duarte","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"},{"name":"Centre for Interdisciplinary Research in Animal Health (CIISA), Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0696-7322","authenticated-orcid":false,"given":"F\u00e1bio Abade dos","family":"Santos","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"},{"name":"Centre for Interdisciplinary Research in Animal Health (CIISA), Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"given":"Teresa","family":"Fagulha","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"}]},{"given":"Margarida","family":"Henriques","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"}]},{"given":"Fernanda","family":"Ramos","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"}]},{"given":"Ana","family":"Duarte","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"},{"name":"Centre for Interdisciplinary Research in Animal Health (CIISA), Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"given":"Tiago","family":"Lu\u00eds","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4832-9898","authenticated-orcid":false,"given":"Ricardo","family":"Parreira","sequence":"additional","affiliation":[{"name":"Institute of Hygiene and Tropical Medicine (IHMT), NOVA University of Lisbon, Rua da Junqueira 100, 1349-008 Lisbon, Portugal"},{"name":"Global Health and Tropical Medicine (GHTM), Rua da Junqueira 100, 1349-008 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6246-1983","authenticated-orcid":false,"given":"S\u00edlvia C.","family":"Barros","sequence":"additional","affiliation":[{"name":"National Institute of Agrarian and Veterinarian Research (INIAV, I.P.), Av. da Rep\u00fablica, Quinta do Marqu\u00eas, 2780-157 Oeiras, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"197770","DOI":"10.1016\/j.virusres.2019.197770","article-title":"Flavivirus Infection\u2014A Review of Immunopathogenesis, Immunological Response, and Immunodiagnosis","volume":"274","author":"Chong","year":"2019","journal-title":"Virus Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"114229","DOI":"10.1016\/j.jviromet.2021.114229","article-title":"A Two-Branched Upgrade to Demonstrate ITV Transmission by Blood-Sucking Insects","volume":"296","author":"Behar","year":"2021","journal-title":"J. Virol. Methods"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1099\/vir.0.061465-0","article-title":"Bagaza Virus and Israel Turkey Meningoencephalomyelitis Virus Are a Single Virus Species","volume":"95","author":"Davidson","year":"2014","journal-title":"J. Gen. Virol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"376","DOI":"10.4269\/ajtmh.1978.27.376","article-title":"Bagaza (BAG)","volume":"27","author":"Digoutte","year":"1978","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.0269-283X.2005.00564.x","article-title":"Mosquito Vectors of the 1998-1999 Outbreak of Rift Valley Fever and other Arboviruses (Bagaza, Sanar, Wesselsbron and West Nile) in Mauritania and Senegal","volume":"19","author":"Diallo","year":"2005","journal-title":"Med. Vet. 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Dis."}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/12\/2\/150\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:07:50Z","timestamp":1760119670000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/12\/2\/150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,17]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["pathogens12020150"],"URL":"https:\/\/doi.org\/10.3390\/pathogens12020150","relation":{},"ISSN":["2076-0817"],"issn-type":[{"type":"electronic","value":"2076-0817"}],"subject":[],"published":{"date-parts":[[2023,1,17]]}}}