{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T17:17:28Z","timestamp":1774891048600,"version":"3.50.1"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Fund (ERDF) through the Northern Regional Operational Programme","award":["NORTE-01-0247-FEDER-047239"],"award-info":[{"award-number":["NORTE-01-0247-FEDER-047239"]}]},{"name":"European Regional Development Fund (ERDF) through the Northern Regional Operational Programme","award":["UIDB\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020"]}]},{"name":"European Regional Development Fund (ERDF) through the Northern Regional Operational 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(POFC)","award":["UIDB\/50006\/2020"],"award-info":[{"award-number":["UIDB\/50006\/2020"]}]},{"name":"European Regional Development Fund (ERDF) through the COMPETE\u2014Programa Operacional Fatores de Competitividade (POFC)","award":["UIDP\/50006\/2020"],"award-info":[{"award-number":["UIDP\/50006\/2020"]}]},{"name":"European Regional Development Fund (ERDF) through the COMPETE\u2014Programa Operacional Fatores de Competitividade (POFC)","award":["PT2020"],"award-info":[{"award-number":["PT2020"]}]},{"name":"European Regional Development Fund (ERDF) through the COMPETE\u2014Programa Operacional Fatores de Competitividade (POFC)","award":["NORTE-01-0247-FEDER-047239"],"award-info":[{"award-number":["NORTE-01-0247-FEDER-047239"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["NORTE-01-0247-FEDER-047239"],"award-info":[{"award-number":["NORTE-01-0247-FEDER-047239"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDB\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDP\/04423\/2020"],"award-info":[{"award-number":["UIDP\/04423\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDP\/04378\/2020"],"award-info":[{"award-number":["UIDP\/04378\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDB\/04378\/2020"],"award-info":[{"award-number":["UIDB\/04378\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDB\/50006\/2020"],"award-info":[{"award-number":["UIDB\/50006\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["UIDP\/50006\/2020"],"award-info":[{"award-number":["UIDP\/50006\/2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["PT2020"],"award-info":[{"award-number":["PT2020"]}]},{"name":"national funding from project 47239-Cork2Cosmetic","award":["NORTE-01-0247-FEDER-047239"],"award-info":[{"award-number":["NORTE-01-0247-FEDER-047239"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>Quercus suber is considered a sustainable tree mainly due to its outer layer (cork) capacity to regenerate after each harvesting cycle. Cork bark is explored for several application; however, its industrial transformation generates a significant amount of waste. Recently, cork by-products have been studied as a supplier of bioactive ingredients. This work aimed to explore whether near infrared spectroscopy (NIRS), a non-destructive analysis, can be employed as a screening device for selecting cork by-products with higher potential for bioactives extraction. A total of 29 samples of cork extracts were analysed regarding their qualitative composition. Partial least squares (PLS) models were developed for quantification purposes, and R2P and RER values of 0.65 and above 4, respectively, were obtained. Discrimination models, performed through PLS-DA, yielded around 80% correct predictions, revealing that four out of five of samples were correctly discriminated, thus revealing that NIR can be successfully applied for screening purposes.<\/jats:p>","DOI":"10.3390\/ph17020180","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T07:49:47Z","timestamp":1706600987000},"page":"180","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Application of NIR Spectroscopy for the Valorisation of Cork By-Products: A Feasibility Study over the Screening and Discrimination of Chemical Compounds of Interest"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-7643","authenticated-orcid":false,"given":"Ricardo N. M. J.","family":"P\u00e1scoa","sequence":"first","affiliation":[{"name":"Associated Laboratory for Green Chemistry\/Network of Chemistry and Technology, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"}]},{"given":"Cl\u00e1udia","family":"Pinto","sequence":"additional","affiliation":[{"name":"Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"},{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3570-3032","authenticated-orcid":false,"given":"Liliana","family":"Rego","sequence":"additional","affiliation":[{"name":"Applied Molecular Biosciences Unit, MedTech, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"},{"name":"Associate Laboratory i4HB\u2014Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"}]},{"given":"Joana Rocha e.","family":"Silva","sequence":"additional","affiliation":[{"name":"Dimas & Silva, Lda. Industry, Rua Central de Goda 345, 4535-167 Mozelos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3320-730X","authenticated-orcid":false,"given":"Maria E.","family":"Tiritan","sequence":"additional","affiliation":[{"name":"Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"},{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"},{"name":"Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0715-1779","authenticated-orcid":false,"given":"Honorina","family":"Cidade","sequence":"additional","affiliation":[{"name":"Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"},{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1498-048X","authenticated-orcid":false,"given":"Isabel F.","family":"Almeida","sequence":"additional","affiliation":[{"name":"Applied Molecular Biosciences Unit, MedTech, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"},{"name":"Associate Laboratory i4HB\u2014Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Teixeira, R.T. 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