{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:52:52Z","timestamp":1760550772184,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T00:00:00Z","timestamp":1550188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["POCI-01-0145-FEDER-PTDC\/QEQ-MED\/0262\/2014","POCI-01-0145-FEDER-007630"],"award-info":[{"award-number":["POCI-01-0145-FEDER-PTDC\/QEQ-MED\/0262\/2014","POCI-01-0145-FEDER-007630"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PT2020\/CENTRO2020","award":["CENTRO-01-0145-FEDER-000014\/MATIS"],"award-info":[{"award-number":["CENTRO-01-0145-FEDER-000014\/MATIS"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceutics"],"abstract":"<jats:p>Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of interesting features makes tetrapyrrolic macrocycles suitable for use as theranostic agents whose full potential can be achieved using nanocarriers. This review provides an overview on nanotheranostic agents based on polymeric micelles and porphyrins developed so far.<\/jats:p>","DOI":"10.3390\/pharmaceutics11020081","type":"journal-article","created":{"date-parts":[[2019,2,17]],"date-time":"2019-02-17T22:11:50Z","timestamp":1550441510000},"page":"81","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1532-684X","authenticated-orcid":false,"given":"Bruno F. O.","family":"Nascimento","sequence":"first","affiliation":[{"name":"CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal"}]},{"given":"Nelson A. M.","family":"Pereira","sequence":"additional","affiliation":[{"name":"CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4612-7686","authenticated-orcid":false,"given":"Artur J. M.","family":"Valente","sequence":"additional","affiliation":[{"name":"CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3256-4954","authenticated-orcid":false,"given":"Teresa M. V. D.","family":"Pinho e Melo","sequence":"additional","affiliation":[{"name":"CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7460-3758","authenticated-orcid":false,"given":"Marta","family":"Pineiro","sequence":"additional","affiliation":[{"name":"CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2019,2,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3389\/fonc.2017.00310","article-title":"Guidelines for rational cancer therapeutics","volume":"7","author":"Yoo","year":"2017","journal-title":"Front. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/138161210789941847","article-title":"Recent advances in cancer therapy: An overview","volume":"16","author":"Urruticoechea","year":"2010","journal-title":"Curr. 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