{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:27:42Z","timestamp":1772252862332,"version":"3.50.1"},"reference-count":64,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T00:00:00Z","timestamp":1628640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photochem"],"abstract":"<jats:p>The knowledge of the optical properties of biological tissues in a wide spectral range is highly important for the development of noninvasive diagnostic or treatment procedures. The absorption coefficient is one of those properties, from which various information about tissue components can be retrieved. Using transmittance and reflectance spectral measurements acquired from ex vivo rabbit brain cortex samples allowed to calculate its optical properties in the ultraviolet to the near infrared spectral range. Melanin and lipofuscin, the two pigments that are related to the aging of tissues and cells were identified in the cortex absorption. By subtracting the absorption of these pigments from the absorption of the brain cortex, it was possible to evaluate the true ratios for the DNA\/RNA and hemoglobin bands in the cortex\u201412.33-fold (at 260 nm), 12.02-fold (at 411 nm) and 4.47-fold (at 555 nm). Since melanin and lipofuscin accumulation increases with the aging of the brain tissues and are related to the degeneration of neurons and their death, further studies should be performed to evaluate the evolution of pigment accumulation in the brain, so that new optical methods can be developed to aid in the diagnosis and monitoring of brain diseases.<\/jats:p>","DOI":"10.3390\/photochem1020011","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T08:35:52Z","timestamp":1628670952000},"page":"190-208","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Spectral Optical Properties of Rabbit Brain Cortex between 200 and 1000 nm"],"prefix":"10.3390","volume":"1","author":[{"given":"T\u00e2nia M.","family":"Gon\u00e7alves","sequence":"first","affiliation":[{"name":"Physics Department, School of Engineering, Polytechnic Institute of Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2876-3686","authenticated-orcid":false,"given":"In\u00eas S.","family":"Martins","sequence":"additional","affiliation":[{"name":"Physics Department, School of Engineering, Polytechnic Institute of Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"},{"name":"Center of Innovation in Engineering and Industrial Technology, ISEP, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]},{"given":"Hugo F.","family":"Silva","sequence":"additional","affiliation":[{"name":"Physics Department, School of Engineering, Polytechnic Institute of Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"},{"name":"Center of Innovation in Engineering and Industrial Technology, ISEP, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7479-2694","authenticated-orcid":false,"given":"Valery V.","family":"Tuchin","sequence":"additional","affiliation":[{"name":"Science Medical Center, Saratov State University, 83 Astrakhanskaya Str., 410012 Saratov, Russia"},{"name":"Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, 36 Lenin\u2019s av., 634050 Tomsk, Russia"},{"name":"Laboratory of Laser Diagnostics of Technical and Living Systems, Institute of Precision Mechanics and Control Institute of the Russian Academy of Sciences, 24 Rabochaya Str., 410028 Saratov, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0667-3428","authenticated-orcid":false,"given":"Lu\u00eds M.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Physics Department, School of Engineering, Polytechnic Institute of Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"},{"name":"Center of Innovation in Engineering and Industrial Technology, ISEP, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Carvalho, S., Carneiro, I., Henrique, R., Tuchin, V.V., and Oliveira, L. 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