{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T21:38:42Z","timestamp":1774733922068,"version":"3.50.1"},"reference-count":118,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T00:00:00Z","timestamp":1667001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FCT\u2014Foundation for Science and Technology","award":["UIDB\/04326\/2020"],"award-info":[{"award-number":["UIDB\/04326\/2020"]}]},{"name":"FCT\u2014Foundation for Science and Technology","award":["UIDP\/04326\/2020"],"award-info":[{"award-number":["UIDP\/04326\/2020"]}]},{"name":"FCT\u2014Foundation for Science and Technology","award":["LA\/P\/0101\/2020"],"award-info":[{"award-number":["LA\/P\/0101\/2020"]}]},{"name":"FCT\u2014Foundation for Science and 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Employment Stimulus","award":["UIDB\/04326\/2020"],"award-info":[{"award-number":["UIDB\/04326\/2020"]}]},{"name":"FCT Scientific Employment Stimulus","award":["UIDP\/04326\/2020"],"award-info":[{"award-number":["UIDP\/04326\/2020"]}]},{"name":"FCT Scientific Employment Stimulus","award":["LA\/P\/0101\/2020"],"award-info":[{"award-number":["LA\/P\/0101\/2020"]}]},{"name":"FCT Scientific Employment Stimulus","award":["PTDC\/CVT-CVT\/28876\/2017"],"award-info":[{"award-number":["PTDC\/CVT-CVT\/28876\/2017"]}]},{"name":"FCT Scientific Employment Stimulus","award":["PTDC\/BAAAGR\/1391\/2020"],"award-info":[{"award-number":["PTDC\/BAAAGR\/1391\/2020"]}]},{"name":"FCT Scientific Employment Stimulus","award":["EMBRC.PT ALG-01-0145-FEDER-022121"],"award-info":[{"award-number":["EMBRC.PT ALG-01-0145-FEDER-022121"]}]},{"name":"FCT Scientific Employment Stimulus","award":["UIDP\/04326\/2020"],"award-info":[{"award-number":["UIDP\/04326\/2020"]}]},{"name":"FCT Scientific Employment Stimulus","award":["CEECIND\/00425\/2017"],"award-info":[{"award-number":["CEECIND\/00425\/2017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>This work searched for the phyto-therapeutic potential and nutritional value of seeds from the halophyte Cladium mariscus L. (Pohl.), aiming at its use as a source of bioactive ingredients for the food industry. Hence, the nutritional profile, including minerals, of seeds biomass was determined; food-grade samples were prepared, and their phytochemical fingerprinting assessed. Extracts were evaluated for in vitro antioxidant potential, inhibitory capacity towards enzymes related to neuroprotection, diabetes, and hyperpigmentation, and anti-inflammatory properties, along with a toxicological assessment. Sawgrass seeds can be considered a proper nutritional source with a good supply of minerals. All extracts had a high level of total phenolics (65.3\u2013394.4 mg GAE\/g DW) and showed a chemically rich and diverse profile of metabolites that have several biological properties described (e.g., antioxidant, anti-inflammatory). Extracts had no significant toxicity (cell viabilities &gt; 80%) and were overall strong antioxidants (particularly at radical scavenging and reducing iron), effective tyrosinase inhibitors (55\u201371 mg KAE\/g DW), showed anti-inflammatory properties (30\u201360% NO decrease), and had moderate capacity to inhibit enzymes related to neuroprotection (AChE 3.7\u20134.2, BChE 4.3\u20136.0 mg GALE\/g DW) and diabetes (\u03b1-glucosidase 1.0\u20131.1, \u03b1-amylase 0.8\u20131.1 mmol ACAE\/g). Altogether, results suggest that sawgrass seeds have the potential to be exploited as a new food product and are a reservoir of bioactive molecules with prospective applications as ingredients for value-added, functional, and\/or preservative food products.<\/jats:p>","DOI":"10.3390\/plants11212910","type":"journal-article","created":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T09:01:42Z","timestamp":1667120502000},"page":"2910","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Nutritional and Phyto-Therapeutic Value of the Halophyte Cladium mariscus L. (Pohl.): A Special Focus on Seeds"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8732-710X","authenticated-orcid":false,"given":"Maria Jo\u00e3o","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Centre of Marine Sciences CCMAR, Faculty of Sciences and Technology, Campus of Gambelas, University of Algarve, 8005-139 Faro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4338-7703","authenticated-orcid":false,"given":"Lu\u00edsa","family":"Cust\u00f3dio","sequence":"additional","affiliation":[{"name":"Centre of Marine Sciences CCMAR, Faculty of Sciences and Technology, Campus of Gambelas, University of Algarve, 8005-139 Faro, Portugal"}]},{"given":"D\u00e9bora","family":"Mecha","sequence":"additional","affiliation":[{"name":"Centre of Marine Sciences CCMAR, Faculty of Sciences and Technology, Campus of Gambelas, University of Algarve, 8005-139 Faro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6548-7823","authenticated-orcid":false,"given":"Gokhan","family":"Zengin","sequence":"additional","affiliation":[{"name":"Department of Biology, Science Faculty, Selcuk University, 42130 Konya, Turkey"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1846-3236","authenticated-orcid":false,"given":"Zolt\u00e1n","family":"Czi\u00e1ky","sequence":"additional","affiliation":[{"name":"Agricultural and Molecular Research and Service Institute, University of Ny\u00edregyh\u00e1za, 4400 Ny\u00edregyh\u00e1za, Hungary"}]},{"given":"Gyula","family":"Sotk\u00f3","sequence":"additional","affiliation":[{"name":"Sotiva Seed Ltd., 4440 Tiszavasv\u00e1ri, Hungary"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1131-8773","authenticated-orcid":false,"given":"Catarina Guerreiro","family":"Pereira","sequence":"additional","affiliation":[{"name":"Centre of Marine Sciences CCMAR, Faculty of Sciences and Technology, Campus of Gambelas, University of Algarve, 8005-139 Faro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3389\/fchem.2016.00032","article-title":"Nutrient value of leaf vs. seed","volume":"4","author":"Edelman","year":"2016","journal-title":"Front. 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