{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:50:38Z","timestamp":1765547438661,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT\/MCTES) through project NemACT","doi-asserted-by":"publisher","award":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"],"award-info":[{"award-number":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"structural funding CE3C","award":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"],"award-info":[{"award-number":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"]}]},{"name":"CHANGE","award":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"],"award-info":[{"award-number":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"]}]},{"name":"GreenIT","award":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"],"award-info":[{"award-number":["10.54499\/2022.00359.CEECIND\/CP1737\/CT0002","10.54499\/UIDB\/00329\/2020","10.54499\/LA\/P\/0121\/2020","10.54499\/UIDB\/04551\/2020","10.54499\/UIDP\/04551\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Corymbia citriodora is a eucalypt tree of significant economic value due to its essential oils (EOs), rich in citronellal, citronellol, and other oxygenated monoterpenes with diverse biological activities. Its EOs show potential for the formulation of biopesticides with a lower impact on the environment and human health. This study evaluated the in vitro nematicidal activity of C. citriodora EOs, obtained from in vivo and in vitro grown plants, and their main volatile compounds against the pinewood nematode (PWN, Bursaphelenchus xylophilus), a major phytosanitary threat. The impact of their main compounds on the environment and human health was assessed using available experimental data and predictions from specialized software. Citronellal and citronellol were the most active EO compounds and exhibited EC50 values comparable to the pesticide emamectin benzoate (0.364 \u00b1 0.009 mg\/mL). They also displayed superior safety profiles, with reduced environmental persistence and toxicity to non-target organisms. Furthermore, C. citriodora shoots were efficiently propagated through an in vitro system and their volatile profile was characterized by a dominance of citronellal (64%), and citronellol (10%), which highlights their potential as a scalable and sustainable source of nematicidal compounds. Remarkably, the EO of C. citriodora in vitro shoots was strongly active against the PWN, exhibiting the lowest EC50 (0.239 \u00b1 0.002 mg\/mL) obtained. These findings underline the viability of C. citriodora EOs as a promising alternative for sustainable pest management, addressing the urgent need for environmentally friendly and health-conscious biopesticides while providing a renewable approach to nematode control.<\/jats:p>","DOI":"10.3390\/plants14131892","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T03:05:27Z","timestamp":1750388727000},"page":"1892","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["In Vivo and In Vitro Grown Lemon-Scented Gum as a Source of Nematicidal Essential Oil Compounds"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2817-7943","authenticated-orcid":false,"given":"Jorge M. S.","family":"Faria","sequence":"first","affiliation":[{"name":"INIAV, I.P., National Institute for Agrarian and Veterinary Research, Quinta do Marqu\u00eas, 2780-159 Oeiras, Portugal"},{"name":"GREEN-IT Bioresources for Sustainability, Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, Universidade Nova de Lisboa (ITQB NOVA), Av. da Rep\u00fablica, 2780-157 Oeiras, Portugal"}]},{"given":"Gon\u00e7alo","family":"Pereira","sequence":"additional","affiliation":[{"name":"INIAV, I.P., National Institute for Agrarian and Veterinary Research, Quinta do Marqu\u00eas, 2780-159 Oeiras, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3239-3190","authenticated-orcid":false,"given":"Ana Cristina","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"CE3C, Centre for Ecology, Evolution and Environmental Changes & CHANGE\u2014Global Change and Sustainability Institute, Faculdade de Ci\u00eancias da Universidade de Lisboa, DBV, C2, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5660-2877","authenticated-orcid":false,"given":"Pedro","family":"Barbosa","sequence":"additional","affiliation":[{"name":"CE3C, Centre for Ecology, Evolution and Environmental Changes & CHANGE\u2014Global Change and Sustainability Institute, Faculdade de Ci\u00eancias da Universidade de Lisboa, DBV, C2, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"MED, Mediterranean Institute for Agriculture, Environment and Development & CHANGE\u2014Global Change and Sustainability Institute, Institute for Advanced Studies and Research, \u00c9vora University, P\u00f3lo da Mitra, Ap. 94, 7006-554 \u00c9vora, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"152435","DOI":"10.1016\/j.flora.2023.152435","article-title":"Ecological Adaptation of Australian Myrtaceae Through the Leaf Waxes Analysis: Corymbia citriodora, Eucalyptus gunnii, and Eucalyptus globulus","volume":"310","author":"Rocha","year":"2024","journal-title":"Flora"},{"key":"ref_2","first-page":"8000780","article-title":"Engineering Wood Products from Eucalyptus Spp.","volume":"2022","author":"Hua","year":"2022","journal-title":"Adv. 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