{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:53:13Z","timestamp":1760151193035,"version":"build-2065373602"},"reference-count":43,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FCT - Foundation for Science and Technology","award":["UIDB\/04423\/2020 and UIDP\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020 and UIDP\/04423\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pollutants"],"abstract":"<jats:p>The aim of the present work was to evaluate the influence of two different pharmaceutical compounds (bezafibrate and paroxetine) on the phytoremediation potential of Phragmites australis in an estuarine medium contaminated by copper. Plants were exposed for seven days to a simplified estuarine medium, elutriate solution, with or without sediment. The medium was doped with copper and bezafibrate or paroxetine. P. australis plants were able to accumulate a significant amount of Cu, particularly in their roots (600 and 250 times increase in copper levels in the absence and presence of sediment, respectively), corroborating the phytostabilization potential of salt marsh plants. Metal uptake and translocation was significantly lower in the presence of sediment (Cu in leaves increased 20 times in the absence and only 4 times in the presence of sediment). An effect of either pharmaceutical compound on metal accumulation was not observed (levels of Cu in plants tissues were in general identical) but, in the presence of sediment, both bezafibrate and paroxetine changed Cu solubility in elutriate solution, either decreasing or increasing it. The current study highlights the possible influence the presence of contaminants of different characteristics (inorganic and organic contaminants) can have on salt marsh phytoremediation potential in the long run, and the effects pollutants might have in the environment.<\/jats:p>","DOI":"10.3390\/pollutants2010006","type":"journal-article","created":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T20:34:45Z","timestamp":1644784485000},"page":"42-52","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmaceuticals Influence on Phragmites australis Phytoremediation Potential in Cu Contaminated Estuarine Media"],"prefix":"10.3390","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0977-9669","authenticated-orcid":false,"given":"Pedro","family":"Fraga-Santiago","sequence":"first","affiliation":[{"name":"Facultad de Biolog\u00eda, Campus Vida, Universidad de Santiago de Compostela, Calle Lope G\u00f3mez de Marzoa, s\/n, Santiago de Compostela, 15782 La Coruna, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2264-0805","authenticated-orcid":false,"given":"Sofia","family":"Dias","sequence":"additional","affiliation":[{"name":"CIIMAR\u2014Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leix\u00f5es, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"},{"name":"Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre 790, 4150-171 Porto, Portugal"}]},{"given":"Cristiana","family":"Silva","sequence":"additional","affiliation":[{"name":"CIIMAR\u2014Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leix\u00f5es, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"},{"name":"Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre 790, 4150-171 Porto, Portugal"}]},{"given":"Carlos R.","family":"Gomes","sequence":"additional","affiliation":[{"name":"CIIMAR\u2014Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leix\u00f5es, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"},{"name":"Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre 790, 4150-171 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6836-0331","authenticated-orcid":false,"given":"C. Marisa R.","family":"Almeida","sequence":"additional","affiliation":[{"name":"CIIMAR\u2014Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leix\u00f5es, Avenida General Norton de Matos, S\/N, 4450-208 Matosinhos, Portugal"},{"name":"Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre 790, 4150-171 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.ecss.2010.02.015","article-title":"Estuarine microbial community characteristics as indicators of human-induced changes (Senegal River, West Africa)","volume":"87","author":"Bouvy","year":"2010","journal-title":"Estuar. Coast. 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