{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T04:54:22Z","timestamp":1768452862677,"version":"3.49.0"},"reference-count":10,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Polymeric carriers play a key role in modern biomedical and nanomedicine applications [...]<\/jats:p>","DOI":"10.3390\/polym13081261","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T10:58:07Z","timestamp":1618311487000},"page":"1261","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Polymeric Carriers for Biomedical and Nanomedicine Application"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8777-5877","authenticated-orcid":false,"given":"Sofia A. Costa","family":"Lima","sequence":"first","affiliation":[{"name":"LAQV, REQUIMTE, Departamento de Ci\u00eancias Qu\u00edmicas, Faculdade de Farm\u00e1cia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0736-2835","authenticated-orcid":false,"given":"Salette","family":"Reis","sequence":"additional","affiliation":[{"name":"LAQV, REQUIMTE, Departamento de Ci\u00eancias Qu\u00edmicas, Faculdade de Farm\u00e1cia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Andrade, R.G.D., Reis, B., Costas, B., Lima, S.A.C., and Reis, S. (2021). Modulation of Macrophages M1\/M2 Polarization Using Carbohydrate-Functionalized Polymeric Nanoparticles. Polymers, 13.","DOI":"10.3390\/polym13010088"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Pontillo, A.R.N., Konstanteli, E., Bairaktari, M.M., and Detsi, A. (2021). Encapsulation of the Natural Product Tyrosol in Carbohydrate Nanosystems and Study of Their Binding with ctDNA. Polymers, 13.","DOI":"10.3390\/polym13010087"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Sabbagh, H.A.K., Hussein-Al-Ali, S.H., Hussein, M.Z., Abudayeh, Z., Ayoub, R., and Abudoleh, S.M. (2020). A Statistical Study on the Development of Metronidazole-Chitosan-Alginate Nanocomposite Formulation Using the Full Factorial Design. Polymers, 12.","DOI":"10.20944\/preprints202001.0234.v1"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Duskey, J.T., Baraldi, C., Gamberini, M.C., Ottonelli, I., Da Ros, F., Tosi, G., Forni, F., Vandelli, M.A., and Ruozi, B. (2020). Investigating Novel Syntheses of a Series of Unique Hybrid PLGA-Chitosan Polymers for Potential Therapeutic Delivery Applications. Polymers, 12.","DOI":"10.3390\/polym12040823"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Shin, H.J., Park, H., Shin, N., Kwon, H.H., Yin, Y., Hwang, J.-A., Kim, S.I., Kim, S.R., Kim, S., and Joo, Y. (2020). p47phox siRNA-Loaded PLGA Nanoparticles Suppress ROS\/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis. Polymers, 12.","DOI":"10.3390\/polym12020443"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Lima, A.F., Amado, I.R., and Pires, L.R. (2020). Poly(d,l-lactide-co-glycolide) (PLGA) Nanoparticles Loaded with Proteolipid Protein (PLP)\u2014Exploring a New Administration Route. Polymers, 12.","DOI":"10.3390\/polym12123063"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Zhang, Y., Lane, M.E., and Moore, D.J. (2020). An Investigation of the Influence of PEG 400 and PEG-6-Caprylic\/Capric Glycerides on Dermal Delivery of Niacinamide. Polymers, 12.","DOI":"10.3390\/polym12122907"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Ghose, A., Nabi, B., Rehman, S., Md, S., Alhakamy, N.A., Ahmad, O.A.A., Baboota, S., and Ali, J. (2020). Development and Evaluation of Polymeric Nanosponge Hydrogel for Terbinafine Hydrochloride: Statistical Optimization, In Vitro and In Vivo Studies. Polymers, 12.","DOI":"10.3390\/polym12122903"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Van Gheluwe, L., Buchy, E., Chourpa, I., and Munnier, E. (2020). Three-Step Synthesis of a Redox-Responsive Blend of PEG\u2013block\u2013PLA and PLA and Application to the Nanoencapsulation of Retinol. Polymers, 12.","DOI":"10.3390\/polym12102350"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Cano-Cortes, M.V., Laz-Ruiz, J.A., Diaz-Mochon, J.J., and Sanchez-Martin, R.M. (2020). Characterization and Therapeutic Effect of a pH Stimuli Responsive Polymeric Nanoformulation for Controlled Drug Release. Polymers, 12.","DOI":"10.3390\/polym12061265"}],"container-title":["Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4360\/13\/8\/1261\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:47:34Z","timestamp":1760161654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4360\/13\/8\/1261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,13]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,4]]}},"alternative-id":["polym13081261"],"URL":"https:\/\/doi.org\/10.3390\/polym13081261","relation":{},"ISSN":["2073-4360"],"issn-type":[{"value":"2073-4360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,13]]}}}