{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:43:51Z","timestamp":1767008631272,"version":"build-2065373602"},"reference-count":62,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Changes in the properties of resin-based polymers exposed to the oral environment can emerge when chlorhexidine (CHX) is incorporated to develop bioactive systems for treating denture stomatitis. Three reline resins loaded with CHX were prepared: 2.5 wt% in Kooliner (K), 5 wt% in Ufi Gel Hard (UFI), and Probase Cold (PC). A total of 60 specimens were submitted to physical aging (1000 cycles of thermal fluctuations, 5\u201355 \u00b0C) or chemical aging (28 days of pH fluctuations in artificial saliva, 6 h at pH = 3, 18 h at pH = 7). Knoop microhardness (30 s, 98 mN), 3-point flexural strength (5 mm\/min), and surface energy were tested. Color changes (\u0394E) were determined using the CIELab system. Data were submitted to non-parametric tests (\u03b1 = 0.05). After aging, bioactive K and UFI specimens were not different from the controls (resins without CHX) in mechanical and surface properties. Thermally aged CHX-loaded PC specimens showed decreased microhardness and flexural strength but not under adequate levels for function. The color change was observed in all CHX-loaded specimens that underwent chemical aging. The long-term use of CHX bioactive systems based on reline resins generally does not impair removable dentures\u2019 proper mechanical and aesthetic functions.<\/jats:p>","DOI":"10.3390\/polym15112549","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T02:12:45Z","timestamp":1685585565000},"page":"2549","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Understanding the Mechanical, Surface, and Color Behavior of Oral Bioactive Prosthetic Polymers under Biodegradation Processes"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4327-1372","authenticated-orcid":false,"given":"Cristina B.","family":"Neves","sequence":"first","affiliation":[{"name":"Biomedical and Oral Sciences Research Unit (UICOB), Faculdade de Medicina Dent\u00e1ria, Universidade de Lisboa, 1600-277 Lisboa, Portugal"}]},{"given":"Joana","family":"Costa","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinar Research (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5058-6554","authenticated-orcid":false,"given":"Jaime","family":"Portugal","sequence":"additional","affiliation":[{"name":"Biomedical and Oral Sciences Research Unit (UICOB), Faculdade de Medicina Dent\u00e1ria, Universidade de Lisboa, 1600-277 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8498-5892","authenticated-orcid":false,"given":"Ana F.","family":"Bettencourt","sequence":"additional","affiliation":[{"name":"Research Institute for Medicines (iMed.ULisboa), Faculdade de Farm\u00e1cia, Universidade de Lisboa, 1649-003 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/jopr.12537","article-title":"Predictors of Patient Satisfaction with Removable Denture Renewal: A Pilot Study","volume":"27","author":"Cuypers","year":"2018","journal-title":"J. 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