{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:31:36Z","timestamp":1760149896733,"version":"build-2065373602"},"reference-count":147,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T00:00:00Z","timestamp":1695945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT-Portugal) and COMPETE (FEDER)","award":["PTDC\/CTMCOM\/1581\/2021","UIDB\/00100\/2020","UIDP\/00100\/2020","LA\/P\/0056\/2020"],"award-info":[{"award-number":["PTDC\/CTMCOM\/1581\/2021","UIDB\/00100\/2020","UIDP\/00100\/2020","LA\/P\/0056\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>This review covers strategies to prepare high-performance emissive polymer nanomaterials, combining very high brightness and photostability, to respond to the drive for better imaging quality and lower detection limits in fluorescence imaging and sensing applications. The more common approaches to obtaining high-brightness nanomaterials consist of designing polymer nanomaterials carrying a large number of fluorescent dyes, either by attaching the dyes to individual polymer chains or by encapsulating the dyes in nanoparticles. In both cases, the dyes can be covalently linked to the polymer during polymerization (by using monomers functionalized with fluorescent groups), or they can be incorporated post-synthesis, using polymers with reactive groups, or encapsulating the unmodified dyes. Silica nanoparticles in particular, obtained by the condensation polymerization of silicon alcoxides, provide highly crosslinked environments that protect the dyes from photodegradation and offer excellent chemical modification flexibility. An alternative and less explored strategy is to increase the brightness of each individual dye. This can be achieved by using nanostructures that couple dyes to plasmonic nanoparticles so that the plasmon resonance can act as an electromagnetic field concentrator to increase the dye excitation efficiency and\/or interact with the dye to increase its emission quantum yield.<\/jats:p>","DOI":"10.3390\/polym15193935","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T05:48:13Z","timestamp":1695966493000},"page":"3935","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bright and Stable Nanomaterials for Imaging and Sensing"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6394-5031","authenticated-orcid":false,"given":"Jos\u00e9 Paulo Sequeira","family":"Farinha","sequence":"first","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Institute of Molecular Sciences and Departamento de Engenharia Qu\u00edmica, Instituto Superior T\u00e9cnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nchembio.1558","article-title":"Tracking Single Molecules at Work in Living Cells","volume":"10","author":"Kusumi","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1021\/cr900263j","article-title":"New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging","volume":"110","author":"Kobayashi","year":"2010","journal-title":"Chem. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.1002\/anie.201105459","article-title":"The Art of Fluorescence Imaging with Chemical Sensors","volume":"51","year":"2012","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1126\/science.1137395","article-title":"Far-Field Optical Nanoscopy","volume":"316","author":"Hell","year":"2007","journal-title":"Science"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1126\/science.1127344","article-title":"Imaging Intracellular Fluorescent Proteins at Nanometer Resolution","volume":"313","author":"Betzig","year":"2006","journal-title":"Science"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/nmeth929","article-title":"Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)","volume":"3","author":"Rust","year":"2006","journal-title":"Nat. Methods"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/nmeth.2843","article-title":"Precisely and accurately localizing single emitters in Fluorescence Microscopy","volume":"11","author":"Deschout","year":"2014","journal-title":"Nat. Methods"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1039\/C3CS60211G","article-title":"Photophysical processes in Single Molecule Organic Fluorescent Probes","volume":"43","author":"Stennett","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4743","DOI":"10.1039\/C4CS00392F","article-title":"An Overview of Nanoparticles Commonly Used in Fluorescent Bioimaging","volume":"44","author":"Wolfbeis","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1247390","DOI":"10.1126\/science.1247390","article-title":"Colloidal Nanoparticles as Advanced Biological Sensors","volume":"346","author":"Howes","year":"2014","journal-title":"Science"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"9243","DOI":"10.1021\/acs.chemrev.0c01176","article-title":"Photoluminescent Nanoparticles for Chemical and Biological Analysis and Imaging","volume":"121","author":"Algar","year":"2021","journal-title":"Chem. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1002\/smll.201503396","article-title":"Fluorescent Polymer Nanoparticles Based on Dyes: Seeking Brighter Tools for Bioimaging","volume":"12","author":"Reisch","year":"2016","journal-title":"Small"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1039\/C3NR05599J","article-title":"Energy Transfer Processes in Dye-Doped Nanostructures Yield Cooperative And Versatile Fluorescent Probes","volume":"6","author":"Genovese","year":"2014","journal-title":"Nanoscale"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1039\/C8CS00805A","article-title":"Emerging Blood\u2013Brain-Barrier-Crossing Nanotechnology for Brain Cancer Theranostics","volume":"48","author":"Tang","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"18082","DOI":"10.1021\/jp906748r","article-title":"Synthesis and Characterization of Perylenediimide Labeled Core-Shell Hybrid Silica-Polymer Nanoparticles","volume":"113","author":"Ribeiro","year":"2009","journal-title":"J. Phys. Chem. C"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2968","DOI":"10.1039\/c3py00059a","article-title":"Biotin-End-Functionalized Highly Fluorescent Water-Soluble Polymers","volume":"4","author":"Relogio","year":"2013","journal-title":"Polym. Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"12934","DOI":"10.1039\/C4NR03718A","article-title":"Tuning the Color and Photostability of Perylene Diimides Inside Polymer Nanoparticles: Towards Biodegradable Substitutes of Quantum Dots","volume":"6","author":"Trofymchuk","year":"2014","journal-title":"Nanoscale"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.1038\/ncomms5089","article-title":"Collective Fluorescence Switching of Counterion-Assembled Dyes in Polymer Nanoparticles","volume":"5","author":"Reisch","year":"2014","journal-title":"Nat. Commun."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"6570","DOI":"10.1039\/C4CS00014E","article-title":"Polymer-Encapsulated Organic Nanoparticles for Fluorescence and Photoacoustic Imaging","volume":"43","author":"Li","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1039\/D2SC04862K","article-title":"Ultrabright AIEdots with tunable narrow emission for multiplexed fluorescence imaging","volume":"14","author":"Zhou","year":"2022","journal-title":"Chem. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1021\/jp055496r","article-title":"Characterizing the Fluorescence Intermittency and Photobleaching Kinetics of Dye Molecules Immobilized on a Glass Surface","volume":"110","author":"Yeow","year":"2006","journal-title":"J. Phys. Chem. A"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nmat2442","article-title":"Understanding Biophysicochemical Interactions at the Nano\u2013Bio Interface","volume":"8","author":"Nel","year":"2009","journal-title":"Nat. Mater."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/nnano.2012.207","article-title":"Biomolecular Coronas Provide the Biological Identity of Nanosized Materials","volume":"7","author":"Monopoli","year":"2012","journal-title":"Nat. Nanotechnol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"3762","DOI":"10.1039\/C3CS60338E","article-title":"Perturbation of Physiological Systems by Nanoparticles","volume":"43","author":"Zhang","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.progpolymsci.2013.11.001","article-title":"Design and Development of Fluorescent Nanostructures for Bioimaging","volume":"39","author":"Chen","year":"2014","journal-title":"Prog. Polym. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.1039\/C3CS60433K","article-title":"Dye Doped Silica Nanoparticles as Luminescent Organized Systems for Nanomedicine","volume":"43","author":"Montalti","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1039\/B600562B","article-title":"Fluorescent Core-Shell Silica Nanoparticles: Towards \u201cLab on a Particle\u201d Architectures for Nanobiotechnology","volume":"35","author":"Burns","year":"2006","journal-title":"Chem. Soc. Rev."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1366\/12-06948","article-title":"Quantum Dots in Bioanalysis: A Review of Applications across Various Platforms for Fluorescence Spectroscopy and Imaging","volume":"67","author":"Petryayeva","year":"2013","journal-title":"Appl. Spectrosc."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"11718","DOI":"10.1021\/acs.chemrev.5b00263","article-title":"Aggregation-Induced Emission: Together We Shine, United We Soar!","volume":"115","author":"Mei","year":"2015","journal-title":"Chem. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"14192","DOI":"10.1002\/anie.202007525","article-title":"Aggregation-Induced Emission (AIE): A Historical Perspective","volume":"59","year":"2020","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1806818","DOI":"10.1002\/adfm.201806818","article-title":"Conjugated Polymer Nanoparticles for Imaging, Cell Activity Regulation, and Therapy","volume":"29","author":"Wang","year":"2019","journal-title":"Adv. Funct. Mater."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2200167","DOI":"10.1002\/adom.202200167","article-title":"Tailoring Lanthanide Upconversion Luminescence through Material Designs and Regulation Strategies","volume":"10","author":"Zheng","year":"2022","journal-title":"Adv. Opt. Mater."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1021\/ar500215v","article-title":"Solution Synthesis, Optical Properties, and Bioimaging Applications of Silicon Nanocrystals","volume":"47","author":"McVey","year":"2014","journal-title":"Acc. Chem. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.progpolymsci.2013.07.005","article-title":"Dendrimer as Nanocarrier for Drug Delivery","volume":"39","author":"Kesharwani","year":"2014","journal-title":"Prog. Polym. Sci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"12217","DOI":"10.1021\/acsami.6b16705","article-title":"Hydrophobic IR-780 Dye Encapsulated in CRGD-Conjugated Solid Lipid Nanoparticles for NIR Imaging-Guided Photothermal Therapy","volume":"9","author":"Kuang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"10346","DOI":"10.1021\/acs.chemrev.5b00703","article-title":"Atomically Precise Colloidal Metal Nanoclusters and Nanoparticles: Fundamentals and Opportunities","volume":"116","author":"Jin","year":"2016","journal-title":"Chem. Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"17199","DOI":"10.1039\/D1NR04939A","article-title":"Encapsulation of Gold Nanoclusters: Stabilization and More","volume":"13","author":"Casteleiro","year":"2021","journal-title":"Nanoscale"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"11827","DOI":"10.1039\/D2TC02044K","article-title":"Synthesis, optical properties and applications of red\/near-infrared carbon dots","volume":"10","author":"Han","year":"2022","journal-title":"J. Mater. Chem. C"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"13079","DOI":"10.1021\/acsanm.1c02600","article-title":"Enhanced Photodynamic Therapy Effects of Graphene Quantum Dots Conjugated with Aminoporphyrin","volume":"4","author":"Santos","year":"2021","journal-title":"ACS Appl. Nano Mater."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1126\/science.1104274","article-title":"Quantum Dots for Live Cells, In Vivo Imaging, and Diagnostics","volume":"307","author":"Michalet","year":"2005","journal-title":"Science"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nmat3539","article-title":"Compact High-Quality CdSe\u2013CdS Core\u2013Shell Nanocrystals with Narrow Emission Linewidths and Suppressed Blinking","volume":"12","author":"Chen","year":"2013","journal-title":"Nat. Mater."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.nantod.2012.10.006","article-title":"Lanthanide-Doped Up-Converting Nanoparticles: Merits and Challenges","volume":"7","author":"Gnach","year":"2012","journal-title":"Nano Today"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"6924","DOI":"10.1039\/c3cs60060b","article-title":"Lanthanide-Doped Luminescent Nanoprobes: Controlled Synthesis, Optical Spectroscopy, and Bioapplications","volume":"42","author":"Liu","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"4398","DOI":"10.1039\/c4tb00291a","article-title":"Aggregation Induced Emission-Based Fluorescent Nanoparticles: Fabrication Methodologies and Biomedical Applications","volume":"2","author":"Zhang","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1021\/acs.accounts.8b00060","article-title":"Aggregation-Induced Emission (AIE) Dots: Emerging Theranostic Nanolights","volume":"51","author":"Feng","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.nantod.2014.09.004","article-title":"Carbon dots\u2014Emerging Light Emitters for Bioimaging, Cancer Therapy and Optoelectronics","volume":"9","author":"Hola","year":"2014","journal-title":"Nano Today"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"19214","DOI":"10.1039\/C9NR05647E","article-title":"Carbon Dots: Advances in Nanocarbon Applications","volume":"11","author":"Kang","year":"2019","journal-title":"Nanoscale"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.nantod.2014.02.010","article-title":"Metal Nanoclusters: New Fluorescent Probes for Sensors and Bioimaging","volume":"9","author":"Zhang","year":"2014","journal-title":"Nano Today"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"100767","DOI":"10.1016\/j.nantod.2019.100767","article-title":"Recent Advances in Synthesizing Metal Nanocluster-Based Nanocomposites for Application in Sensing, Imaging and Catalysis","volume":"28","author":"Shang","year":"2019","journal-title":"Nano Today"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"4699","DOI":"10.1039\/C4CS00294F","article-title":"Soft Fluorescent Nanomaterials for Biological and Biomedical Imaging","volume":"44","author":"Peng","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1038\/s41598-017-02678-0","article-title":"Artefact-free Evaluation of Metal Enhanced Fluorescence in Silica Coated Gold Nanoparticles","volume":"7","author":"Ribeiro","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1021\/nl048669h","article-title":"Bioconjugates of CdTe Nanowires and Au Nanoparticles: Plasmon\u2013Exciton Interactions, Luminescence Enhancement, and Collective Effects","volume":"4","author":"Lee","year":"2004","journal-title":"Nano Lett."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2001150","DOI":"10.1002\/adom.202001150","article-title":"Modified Absorption and Emission Properties Leading to Intriguing Applications in Plasmonic-Excitonic Nanostructures","volume":"9","author":"Kumar","year":"2020","journal-title":"Adv. Opt. Mater."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3962","DOI":"10.1039\/C7CS00169J","article-title":"Plasmon-enhanced fluorescence spectroscopy","volume":"46","author":"Li","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Luan, J., Seth, A., Gupta, R., Wang, Z., Rathi, P., Cao, S., Derami, H.G., Tang, R., Xu, B., and Achilefu, S. (2020). Ultrabright Fluorescent Nanoscale Labels for the Femtomolar Detection of Analytes with Standard Bioassays. Nat. Biomed. Eng., 4.","DOI":"10.1038\/s41551-020-0547-4"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.bios.2018.04.007","article-title":"Metal enhanced fluorescence (MEF) for biosensors: General approaches and a review of recent developments","volume":"111","author":"Jeong","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/marc.200500839","article-title":"Experimental Requirements for an Efficient Control of Free-Radical Polymerizations via the Reversible Addition-Fragmentation Chain Transfer (RAFT) Process","volume":"27","author":"Favier","year":"2006","journal-title":"Macromol. Rapid Commun."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"5450","DOI":"10.1039\/C4AY00236A","article-title":"A New Optical Boron Detection Method","volume":"6","author":"Alves","year":"2014","journal-title":"Anal. Methods"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1039\/C6RA25022J","article-title":"Optical Sensing of Aqueous Boron Based on Polymeric Hydroxytriphenylene Derivatives","volume":"7","author":"Areias","year":"2017","journal-title":"RSC Adv."},{"key":"ref_60","unstructured":"Farinha, J.P.S., Alves, S., and Baleiz\u00e3o, C. (2014). Optical Sensors for Boron Detection Based on the Use of 2,3,6,7,10,11-Hexahydroxytriphenylene or Its Derivatives. (PCT\/PT2014\/000007), French Patent."},{"key":"ref_61","unstructured":"Farinha, J.P.S., Alves, S., and Baleiz\u00e3o, C. (2013). Sensores \u00d3ticos para Dete\u00e7\u00e3o de Boro Baseados na Utiliza\u00e7\u00e3o de 2,3,6,7,10,11-Hexahidroxitrifenileno ou seus Derivados. (PT106766), French Patent."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"5933","DOI":"10.1016\/j.polymer.2011.10.041","article-title":"Novel Malachite Green- and Rhodamine B-Labeled Cationic Chain Transfer Agents for RAFT Polymerization","volume":"52","author":"Beija","year":"2011","journal-title":"Polymer"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1039\/D1MA00110H","article-title":"Fluorescent labeling of biocompatible block copolymers: Synthetic strategies and applications in bioimaging","volume":"2","author":"Bou","year":"2021","journal-title":"Mater. Adv."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1021\/ma902103q","article-title":"Thermoresponsive Micelles of Poly(decylacrylamide-b-diethylacrylamide) in Water","volume":"43","author":"Marcelo","year":"2010","journal-title":"Macromolecules"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.polymer.2009.11.055","article-title":"RAFT Polymerization and Self-Assembly of Thermoresponsive Poly(N-decylacrylamide)-b-poly(N,N-diethylacrylamide) Block Copolymers Bearing a Phenanthrene Fluorescent alfa-End Group","volume":"51","author":"Prazeres","year":"2010","journal-title":"Polymer"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1021\/la902510q","article-title":"Schizophrenic Behavior of a Thermoresponsive Double Hydrophilic Diblock Copolymer at the Air-Water Interface","volume":"26","author":"Beija","year":"2010","journal-title":"Langmuir"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"6527","DOI":"10.1021\/la2047646","article-title":"New Insights in the Study of Pyrene Excimer Fluorescence to Characterize Macromolecules and their Supramolecular Assemblies in Solution","volume":"28","author":"Duhamel","year":"2012","journal-title":"Langmuir"},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Besford, Q.A., Schubotz, S., Chae, S., \u00d6zdabak Sert, A.B., Weiss, A.C.G., Auernhammer, G.K., Uhlmann, P., Farinha, J.P.S., and Fery, A. (2022). Molecular Transport within Polymer Brushes: A FRET View at Aqueous Interfaces. Molecules, 27.","DOI":"10.3390\/molecules27093043"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.1021\/acsnano.2c00277","article-title":"Mechanofluorescent Polymer Brush Surfaces that Spatially Resolve Surface Solvation","volume":"16","author":"Besford","year":"2022","journal-title":"ACS Nano"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"8639","DOI":"10.1016\/j.polymer.2004.10.056","article-title":"Well-Defined Polymer Precursors Synthesized by RAFT Polymerization of N,N-dimethylacrylamide\/N-acryloxysuccinimide: Random and Block Copolymers","volume":"45","author":"Charreyre","year":"2004","journal-title":"Polymer"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"10799","DOI":"10.1021\/ma051701p","article-title":"Effect of Surfactant on the Intra- and Intermolecular Association of Hydrophobically Modified Poly(N,N-dimethylacrylamide)","volume":"38","author":"Martinho","year":"2005","journal-title":"Macromolecules"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1021\/ma070444g","article-title":"Understanding and Avoiding Fluorescence Quenching in Polymers Obtained by RAFT","volume":"40","author":"Farinha","year":"2007","journal-title":"Macromolecules"},{"key":"ref_73","unstructured":"Charreyre, M.-T., Farinha, J.P.S., Mandrand, B., Martinho, J.M.G., and Rel\u00f3gio, P. (2012). Fluorescent Polymers Soluble in an Aqueous Solution and Preparation Thereof. (8,133,411B2), U.S. Patent."},{"key":"#cr-split#-ref_74.1","unstructured":"Charreyre, M.-T., Farinha, J.P.S., Mandrand, B., Martinho, J.M.G., and Rel\u00f3gio, P. (2006). Fluorescent Polymer Soluble in an Aqueous Solution, Useful in Medical Diagnostics or Therapeutics to Detect a Target Molecule, Comprises Fluorophores, Which Are Distributed on a Polymer and Exhibit Specific Properties. (EP1899434), WO2007003781, 30 June 2006"},{"key":"#cr-split#-ref_74.2","doi-asserted-by":"crossref","unstructured":"U.S. Patent 2,008,290,321, 30 June 2006.","DOI":"10.1007\/s10824-006-9022-7"},{"key":"ref_75","unstructured":"Charreyre, M.-T., Mandrand, B., Martinho, J.M.G., Rel\u00f3gio, P., and Farinha, J.P.S. (2007). New Fluorescent Polymer Soluble in Water, Useful for Delivering Pharmaceuticals and for Diagnosis, Comprises Many Fluorophores Distributed over the Polymer Chain. (FR2887892)."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"17546","DOI":"10.1038\/s41598-020-74621-9","article-title":"Multiscale fluorescent tracking of immune cells in the liver with a highly biocompatible far-red emitting polymer probe","volume":"10","author":"Daniel","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"12841","DOI":"10.1021\/acsomega.9b01643","article-title":"Advanced Fluorescent Polymer Probes for the Site-Specific Labeling of Proteins in Live Cells Using the HaloTag Technology","volume":"4","author":"Berki","year":"2019","journal-title":"ACS Omega"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1021\/acs.biomac.1c01706","article-title":"Fluorescent Polymer-AS1411-Aptamer Probe for dSTORM Super-Resolution Imaging of Endogenous Nucleolin","volume":"23","author":"Fabre","year":"2022","journal-title":"Biomacromolecules"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1002\/anie.201205133","article-title":"Highly Fluorescent Semiconducting Polymer Dots for Biology and Medicine","volume":"52","author":"Wu","year":"2013","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"6260","DOI":"10.1021\/cr100132y","article-title":"Nanoparticles of Conjugated Polymers","volume":"110","author":"Pecher","year":"2010","journal-title":"Chem. Rev."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"6620","DOI":"10.1039\/c3cs60036j","article-title":"Conjugated polymer nanoparticles: Preparation, properties, functionalization and biological applications","volume":"42","author":"Feng","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"46562","DOI":"10.1021\/acsami.2c12338","article-title":"Conjugated Polymer Nanoparticles as a Universal High-Affinity Probe for the Selective Detection of Microplastics","volume":"14","author":"Awada","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1002\/smll.201202505","article-title":"Eccentric Loading of Fluorogen with Aggregation-Induced Emission in PLGA Matrix Increases Nanoparticle Fluorescence Quantum Yield for Targeted Cellular Imaging","volume":"9","author":"Geng","year":"2013","journal-title":"Small"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.addr.2013.12.009","article-title":"Nanoprecipitation and the Ouzo Effect: Application to Drug Delivery Devices","volume":"71","author":"Lepeltier","year":"2014","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"5104","DOI":"10.1021\/acsnano.5b00214","article-title":"Charge-Controlled Nanoprecipitation as a Modular Approach to Ultrasmall Polymer Nanocarriers: Making Bright and Stable Nanoparticles","volume":"9","author":"Reisch","year":"2015","journal-title":"ACS Nano"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jconrel.2008.06.015","article-title":"Stability Issues of Polymeric Micelles","volume":"131","author":"Bae","year":"2008","journal-title":"J. Control Release"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1039\/C3PY01197F","article-title":"Homogeneous Near-Infrared Emissive Polymeric Nanoparticles Based on Amphiphilic Diblock Copolymers with Perylene Diimide and PEG Pendants: Self-Assembly Behavior and Cellular Imaging Application","volume":"5","author":"Yang","year":"2014","journal-title":"Polym. Chem."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3184\/030823402103170871","article-title":"Synthesis of 4-aryl-butylamine Fluorescent Probes","volume":"11","author":"Afonso","year":"2002","journal-title":"J. Chem. Res."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.progpolymsci.2010.06.004","article-title":"Dye-labelled polymer chains at specific sites: Synthesis by living\/controlled polymerization","volume":"36","author":"Beija","year":"2011","journal-title":"Prog. Polym. Sci."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"12345","DOI":"10.1021\/la502826r","article-title":"Smart Hybrid Polymer Nanoparticles for High Performance Water-borne Coatings","volume":"30","author":"Fidalgo","year":"2014","journal-title":"Langmuir"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S1359-0294(97)80026-X","article-title":"Latex film formation","volume":"2","author":"Winnik","year":"1997","journal-title":"Curr. Opin. Colloid Interface Sci."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"10591","DOI":"10.1021\/jp8016437","article-title":"Resonance Energy Transfer in Polymer Nanodomains","volume":"112","author":"Martinho","year":"2008","journal-title":"J. Phys. Chem. C"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"11299","DOI":"10.1021\/ja203080p","article-title":"Smart Polymer Nanoparticles Designed for Environmentally Compliant Coatings","volume":"133","author":"Soleimani","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/pola.23786","article-title":"From Polymeric Particles to Multifunctional Nanocapsules for Biomedical Applications Using the Miniemulsion Process","volume":"48","author":"Landfester","year":"2010","journal-title":"J. Polym. Sci. Part A Polym. Chem."},{"key":"ref_95","unstructured":"Farinha, J.P.S., Augusto, V., Baleiz\u00e3o, C., and Berberan e Santos, M. (2010). Method for Producing Polymeric Nano-Particles and Micro-Particles with Encapsulated Fullerenes for Application in Optical Sensors of Temperature and Molecular Oxygen Content. (PT104172), French Patent."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/macp.1995.021960201","article-title":"Polymerization in Microemulsions\u2014A New Approach to Ultrafine, Highly Functionalized Polymer Dispersions","volume":"196","author":"Antonietti","year":"1995","journal-title":"Macromol. Chem. Phys."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1039\/B920673F","article-title":"Oxygen-Proof Fluorescence Temperature Sensing with Pristine C70 Encapsulated in Polymer Nanoparticles","volume":"20","author":"Augusto","year":"2010","journal-title":"J. Mater. Chem."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1021\/ma300090a","article-title":"One-Pot Production of Fluorescent Surface-Labeled Polymeric Nanoparticles via Miniemulsion Polymerization with Bodipy Surfmers","volume":"45","author":"Sauer","year":"2012","journal-title":"Macromolecules"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"11731","DOI":"10.1039\/c2ra22314g","article-title":"Laser Dye Doped Nanoparticles for Highly Photostable Optical Nanoamplifiers","volume":"2","author":"Monguzzi","year":"2012","journal-title":"RSC Adv."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.progpolymsci.2015.10.002","article-title":"Polymerization-Induced Self-Assembly of Block Copolymer Nanoparticles via RAFT Non-Aqueous Dispersion Polymerization","volume":"52","author":"Derry","year":"2016","journal-title":"Prog. Polym. Sci."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s00396-002-0670-7","article-title":"Preparation of a Novel Polymeric Fluorescent Nanoparticle","volume":"280","author":"Gao","year":"2002","journal-title":"Colloid Polym. Sci."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"12776","DOI":"10.1039\/D1NJ01791H","article-title":"Core-functionalized nanoaggregates: Preparation via polymerization-induced self-assembly and their applications","volume":"45","author":"Damsongsang","year":"2021","journal-title":"New J. Chem."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"4393","DOI":"10.1021\/ma050167i","article-title":"Polymer Diffusion in Gel-Containing Poly(vinyl acetate-co-dibutyl daleate) Latex Films","volume":"38","author":"Farinha","year":"2005","journal-title":"Macromolecules"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"7009","DOI":"10.1021\/acs.langmuir.9b00721","article-title":"Controlling Size and Fluorescence of Dye-Loaded Polymer Nanoparticles through Polymer Design","volume":"35","author":"Rosiuk","year":"2019","journal-title":"Langmuir"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"4645","DOI":"10.1039\/C4CS00270A","article-title":"Silica-Based Nanoparticles: A Versatile Tool for the Development of Efficient Imaging Agents","volume":"44","author":"Caltagirone","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Yang, S.B., and Li, Y.S. (2020). Fluorescent hybrid silica nanoparticles and their biomedical applications. Wiley Interdiscip. Rev.\u2014Nanomed. Nanobiotechnol., 12.","DOI":"10.1002\/wnan.1603"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/0021-9797(68)90272-5","article-title":"Controlled Growth of Monodisperse Silica Spheres in the Micron Size Range","volume":"26","author":"Fink","year":"1968","journal-title":"J. Colloid Interface Sci."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1002\/anie.200503075","article-title":"Silica-Based Mesoporous Organic\u2013Inorganic Hybrid Materials","volume":"45","author":"Hoffmann","year":"2006","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S1748-0132(07)70086-5","article-title":"Dye-doped Nanoparticles for Bioanalysis","volume":"2","author":"Yan","year":"2007","journal-title":"Nano Today"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1021\/acs.analchem.6b03117","article-title":"Functional Group Coverage and Conversion Quantification in Nanostructured Silica by 1H-NMR","volume":"89","author":"Crucho","year":"2017","journal-title":"Anal. Chem."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"4579","DOI":"10.1002\/ejic.201500580","article-title":"Multifunctional Hybrid Silica Nanoparticles with a Fluorescent Core and Active Targeting Shell for Fluorescence Imaging Biodiagnostic Applications","volume":"27","author":"Santiago","year":"2015","journal-title":"Eur. J. Inorg. Chem."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1071\/EN19190","article-title":"Electrophoresis as a Simple Method to Detect Deleterious Actions of Engineered Nanoparticles on Living Cells","volume":"17","author":"Vouriot","year":"2020","journal-title":"Environ. Chem."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.dyepig.2014.03.026","article-title":"NIR and Visible Perylenediimide-Silica Nanoparticles for Laser Scanning Bio-imaging","volume":"110","author":"Ribeiro","year":"2014","journal-title":"Dye. Pigment."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"110348","DOI":"10.1016\/j.msec.2019.110348","article-title":"Bioactive Silica Nanoparticles with Calcium and Phosphate for Single Dose Osteogenic Differentiation","volume":"107","author":"Tavares","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_115","unstructured":"Gon\u00e7alves, J.L.M., Baleiz\u00e3o, C., and Farinha, J.P.S. (2021). Soft Matter for Biomedical Applications, Royal Society of Chemistry. [1st ed.]."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1172\/JCI45600","article-title":"Multimodal Silica Nanoparticles are Effective Cancer-Targeted Probes in a Model of Human Melanoma","volume":"121","author":"Benezra","year":"2011","journal-title":"J. Clin. Investig."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"1604634","DOI":"10.1002\/adma.201604634","article-title":"Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles","volume":"29","author":"Croissant","year":"2017","journal-title":"Adv. Mater."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"7216","DOI":"10.1021\/acsnano.0c02289","article-title":"Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake","volume":"14","author":"Zou","year":"2020","journal-title":"ACS Nano"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jcis.2013.03.002","article-title":"Formation of Hybrid Films from Perylenediimide-Labeled Core-Shell Silica-Polymer Nanoparticles","volume":"401","author":"Ribeiro","year":"2013","journal-title":"J. Colloid Interface Sci."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"9171","DOI":"10.1039\/c3ra41199k","article-title":"High Performance NIR Fluorescent Silica Nanoparticles for Bioimaging","volume":"3","author":"Ribeiro","year":"2013","journal-title":"RSC Adv."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"022002","DOI":"10.1088\/2050-6120\/aa8f57","article-title":"NIR-Fluorescent Dye Doped Silica Nanoparticles for in Vivo Imaging, Sensing and Theranostic","volume":"6","author":"Rampazzo","year":"2018","journal-title":"Methods Appl. Fluoresc."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1002\/anie.201301155","article-title":"Prevention of Self-Quenching in Fluorescent Silica Nanoparticles by Efficient Energy Transfer","volume":"52","author":"Genovese","year":"2013","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s00216-006-0452-z","article-title":"FloDots: Luminescent Nanoparticles","volume":"385","author":"Yao","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1021\/ar200018x","article-title":"Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine","volume":"44","author":"Ambrogio","year":"2011","journal-title":"Acc. Chem. Res."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nature09698","article-title":"Probing the Electromagnetic Field of a 15-Nanometre Hotspot by Single Molecule Imaging","volume":"469","author":"Cang","year":"2011","journal-title":"Nature"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1039\/D2CC06178C","article-title":"Plasmonic quenching and enhancement: Metal\u2013quantum dot nanohybrids for fluorescence biosensing","volume":"59","author":"Hildebrandt","year":"2023","journal-title":"Chem. Commun."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.1021\/nn406434y","article-title":"Resonant Plasmonic Enhancement of Single-Molecule Fluorescence by Individual Gold Nanorods","volume":"8","author":"Khatua","year":"2014","journal-title":"ACS Nano"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"113002","DOI":"10.1103\/PhysRevLett.96.113002","article-title":"Enhancement and Quenching of Single-Molecule Fluorescence","volume":"96","author":"Anger","year":"2006","journal-title":"Phys. Rev. Lett."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"8392","DOI":"10.1021\/nn502887j","article-title":"Distance and Plasmon Wavelength Dependent Fluorescence of Molecules Bound to Silica-Coated Gold Nanorods","volume":"8","author":"Abadeer","year":"2014","journal-title":"ACS Nano"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1021\/jp808116y","article-title":"Fluorescence Enhancement of Chromophores Close to Metal Nanoparticles. Optimal Setup Revealed by the Polarizable Continuum Model","volume":"113","author":"Vukovic","year":"2008","journal-title":"J. Phys. Chem. C"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1021\/jp311200r","article-title":"Enhanced Photoluminescence from Micellar Assemblies of Cadmium Sulfide Quantum Dots and Gold Nanoparticles","volume":"117","author":"Ribeiro","year":"2013","journal-title":"J. Phys. Chem. C"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"7017","DOI":"10.1002\/adfm.201503326","article-title":"Plasmon-Enhanced Fluorescence-Based Core-Shell Gold Nanorods as a Near-IR Fluorescent Turn-On Sensor for the Highly Sensitive Detection of Pyrophosphate in Aqueous Solution","volume":"25","author":"Wang","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"26663","DOI":"10.1021\/acs.jpcc.5b08477","article-title":"Study of the Interaction between Gold Nanoparticles and Rose Bengal Fluorophores with Silica Spacers by Time-Resolved Fluorescence Spectroscopy","volume":"119","author":"Lin","year":"2015","journal-title":"J. Phys. Chem. C"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s10895-007-0259-0","article-title":"Plasmonic Enhancement of Single-Molecule Fluorescence Near a Silver Nanoparticle","volume":"17","author":"Fu","year":"2007","journal-title":"J. Fluoresc."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1707003","DOI":"10.1002\/adma.201707003","article-title":"Silica-Coated Plasmonic Metal Nanoparticles in Action","volume":"30","author":"Hanske","year":"2018","journal-title":"Adv. Mater."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"6636","DOI":"10.1021\/nn401775e","article-title":"Distance and Wavelength Dependent Quenching of Molecular Fluorescence by Au@SiO2 Core\u2013Shell Nanoparticles","volume":"7","author":"Reineck","year":"2013","journal-title":"ACS Nano"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1364\/BOE.2.001727","article-title":"Investigating the Distance Limit of a Metal Nanoparticle Based Spectroscopic Ruler","volume":"2","author":"Chatterjee","year":"2011","journal-title":"Biomed. Opt. Express"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"8201","DOI":"10.1021\/acs.langmuir.7b01687","article-title":"Versatile Tetrablock Copolymer Scaffold for Hierarchical Colloidal Nanoparticle Assemblies: Synthesis, Characterization, and Molecular Dynamics Simulation","volume":"33","author":"Marcelo","year":"2017","journal-title":"Langmuir"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1021\/am201858u","article-title":"pH- and Glucose-Responsive Core\u2013Shell Hybrid Nanoparticles with Controllable Metal-Enhanced Fluorescence Effects","volume":"4","author":"Zhang","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1021\/la203704j","article-title":"Control of Metal-Enhanced Fluorescence with pH- and Thermoresponsive Hybrid Microgels","volume":"28","author":"Tang","year":"2011","journal-title":"Langmuir"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/adma.200901263","article-title":"Recent Progress on Silica Coating of Nanoparticles and Related Nanomaterials","volume":"22","year":"2010","journal-title":"Adv. Mater."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1021\/acs.nanolett.0c04303","article-title":"CRISPR-Cas12a-Based Nucleic Acid Amplification-Free DNA Biosensor via Au Nanoparticle-Assisted Metal-Enhanced Fluorescence and Colorimetric Analysis","volume":"21","author":"Choi","year":"2021","journal-title":"Nano Lett."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1039\/D1AN02173G","article-title":"Highly-selective and sensitive plasmon-enhanced fluorescence sensor of aflatoxins","volume":"147","author":"Sergeyeva","year":"2022","journal-title":"Analyst"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"101025","DOI":"10.1016\/j.nanoso.2023.101025","article-title":"Optical coupling of bio-inspired mustard protein-based bimetallic nanohybrids with propagating surface plasmon polaritons for femtomolar nitrite ion sensing: Cellphone-based portable detection device","volume":"35","author":"Ganesh","year":"2023","journal-title":"Nano-Struct. Nano-Objects"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"129410","DOI":"10.1016\/j.colsurfa.2022.129410","article-title":"Encapsulation of gold nanoclusters by photo-initiated miniemulsion polymerization","volume":"648","author":"Casteleiro","year":"2022","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"100694","DOI":"10.1016\/j.colcom.2022.100694","article-title":"Interaction between Gold Nanoclusters and Gold Nanoparticles encapsulated in Polymer Nanoparticles","volume":"52","author":"Casteleiro","year":"2023","journal-title":"Colloid Interface Sci. Commun."}],"container-title":["Polymers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4360\/15\/19\/3935\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:01:47Z","timestamp":1760130107000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4360\/15\/19\/3935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,29]]},"references-count":147,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["polym15193935"],"URL":"https:\/\/doi.org\/10.3390\/polym15193935","relation":{},"ISSN":["2073-4360"],"issn-type":[{"type":"electronic","value":"2073-4360"}],"subject":[],"published":{"date-parts":[[2023,9,29]]}}}