{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:27:51Z","timestamp":1760059671951,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Background: Stereolithography is a rapid prototyping and 3D printing technique that creates solid three-dimensional models. An accurate and functional 3D model using stereolithography is invaluable in scientific research, particularly in studies involving edentulous patients. Additive manufacture and CAD systems help achieve accurate measurements and procedures and be easily replicated by lowering human error mistakes. The main objective of this study was to develop an in vitro simulation model with a reduced alveolar ridge with the same characteristics as mandibular edentulous patients using stereolithography. Methods: A mandibular model with a resorbed mandibular crest was scanned, and the STL model was aligned to the XYZ reference system. A reduction in the alveolar ridge corresponding to the mandibular mucosa of an edentulous patient was achieved. A negative model also derived from the original model was made to ensure the space for oral simulation material. A dimensional stability test was performed to validate the model. Results: The maximal mean displacement of the model was 0.015 mm, and the minimal mean displacement was 0.004 mm. The oral mucosa had a displacement of approximately 1.6 mm. Conclusions: An in vitro 3D simulation model of a complete edentulous patient mucosa was achieved.<\/jats:p>","DOI":"10.3390\/polym17131820","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T05:00:37Z","timestamp":1751259637000},"page":"1820","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three-Dimensional Manufacturing of Mandibular Total Edentulous Simulation Model for In Vitro Studies\u2014Concept and Validation"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0035-1770","authenticated-orcid":false,"given":"Joana","family":"Mendes","sequence":"first","affiliation":[{"name":"UNIPRO\u2014Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences IUCS\/(CESPU), 4585-116 Gandra, Portugal"},{"name":"Departament de Patologia i Terap\u00e8utica Experimental, Facultat de Medicina i Ci\u00e8ncies de la Salut, Universitat de Barcelona (UB), 08007 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4585-4953","authenticated-orcid":false,"given":"Maria Cristina","family":"Manzanares-C\u00e9spedes","sequence":"additional","affiliation":[{"name":"UNIPRO\u2014Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences IUCS\/(CESPU), 4585-116 Gandra, Portugal"},{"name":"Human Anatomy and Embryology Unit, Faculty of Medicine and Health Sciences, University of Barcelona, 08007 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9936-9083","authenticated-orcid":false,"given":"Jos\u00e9 L.","family":"Esteves","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal"}]},{"given":"Jo\u00e3o","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Dental Sciences, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior e Polit\u00e9cnico Universit\u00e1rio\u2013CESPU, 4585-116 Gandra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2532-6288","authenticated-orcid":false,"given":"Lara","family":"Coelho","sequence":"additional","affiliation":[{"name":"UNIPRO\u2014Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences IUCS\/(CESPU), 4585-116 Gandra, Portugal"},{"name":"Departament de Patologia i Terap\u00e8utica Experimental, Facultat de Medicina i Ci\u00e8ncies de la Salut, Universitat de Barcelona (UB), 08007 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6920-5838","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Mendes","sequence":"additional","affiliation":[{"name":"UNIPRO\u2014Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences IUCS\/(CESPU), 4585-116 Gandra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103957","DOI":"10.1016\/j.jdent.2022.103957","article-title":"A Novel Low-Shrinkage Resin for 3D Printing","volume":"118","author":"Ling","year":"2022","journal-title":"J. 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