{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:13:07Z","timestamp":1760145187309,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia (FCT)","doi-asserted-by":"publisher","award":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"],"award-info":[{"award-number":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Instituto Superior T\u00e9cnico for the Scientific Employment","award":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"],"award-info":[{"award-number":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"]}]},{"name":"PhD fellowship","award":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"],"award-info":[{"award-number":["UIDB\/00100\/2020","UIDP\/00100\/2020","IST-ID\/119\/2018","SFRH\/BD\/146426\/2019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Processes"],"abstract":"<jats:p>The microwave-assisted Sonogashira C-C cross-coupling reaction catalysed by Pd ionanofluids based on bis(trifluoromethane-sulfonyl)imide (NTf2) ionic liquids, [Cnmim][NTf2] (n = 4, 6 or 8), is described here. An organic solvent- and Cu(I)-free methodology running under very mild conditions was established by creating in situ catalysts from Pd(II) salts and [Cnmim][NTf2]. The microwave-irradiated catalytic systems quickly yielded almost quantitative conversions of 4-bromoanisole and phenylacetylene (model reaction) into the desired 1-methoxy-4-(phenylethynyl)benzene as a single product, and a good recyclability of the Pd ionanofluids.<\/jats:p>","DOI":"10.3390\/pr12071351","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T03:38:27Z","timestamp":1719805107000},"page":"1351","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Microwave-Assisted Solvent- and Cu(I)-Free Sonogashira C-C Cross-Coupling Catalysed by Pd Ionanofluids"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5501-7913","authenticated-orcid":false,"given":"In\u00eas A. S.","family":"Matias","sequence":"first","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Qu\u00edmica, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4323-4328","authenticated-orcid":false,"given":"Ana P. C.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Qu\u00edmica, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5403-9352","authenticated-orcid":false,"given":"Lu\u00edsa M. D. R. S.","family":"Martins","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Qu\u00edmica, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1016\/S0040-4039(00)91094-3","article-title":"A convenient synthesis of acetylenes: Catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines","volume":"16","author":"Sonogashira","year":"1975","journal-title":"Tetrahedron Lett."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1002\/anie.200602761","article-title":"Palladium-based catalytic systems for the synthesis of conjugated enynes by Sonogashira reactions and related alkynylations","volume":"46","author":"Doucet","year":"2007","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Pereira, M.M., and Calvete, M.J.F. (2018). C-C bond formation in sustainable synthesis of pharmaceuticals. 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