{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T02:49:09Z","timestamp":1769482149766,"version":"3.49.0"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prosthesis"],"abstract":"<jats:p>Background\/Objectives: Implant-supported rehabilitations using the All-on-4 concept represent a viable treatment option for completely edentulous patients. The guided surgery software allows for the performance of a flapless computer-guided surgery with similar results to those achieved through a flap surgery. This study aimed to evaluate the long-term outcomes of complete edentulous implant-supported rehabilitations using an All-on-4 arrangement, following a computer-guided protocol. Methods: A total of 111 patients (68 females, 43 males) with an average age of 60.9 years \u00b1 9.67 years were treated. The primary outcome measures were implant and prosthetic survival. Secondary outcome measures were marginal bone loss (MBL) and the incidence of mechanical and biological complications. Results: Thirty-nine patients were lost to follow-up. Thirty-seven implants and five prostheses failed, rendering a 92.5% implant cumulative survival rate and a 96.2% prosthetic survival rate at 12 years. The average MBL per implant was 1.19 \u00b1 1.16 mm, with 1.26 \u00b1 1.33 mm for axial implants and 1.12 \u00b1 0.95 mm for tilted implants at 10 years. The incidence rate of mechanical complications at the patient level was 90.1% for provisional prostheses and 55.9% for definitive prostheses. The rate of biological complications was 14.3% at the implant level. Conclusions: Full-arch rehabilitations following an All-on-4 implant arrangement and assisted by a computer-guided protocol may be a viable alternative for patients with edentulism\/hopeless teeth in the long term.<\/jats:p>","DOI":"10.3390\/prosthesis8020013","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T16:13:48Z","timestamp":1769444028000},"page":"13","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Computer-Guided Flapless Immediate Function Dental Implants for Full-Arch Rehabilitations Using the All-on-4 Concept: A 12-Year Clinical and 10-Year Radiographic Retrospective Study"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7084-8301","authenticated-orcid":false,"given":"Miguel","family":"de Ara\u00fajo Nobre","sequence":"first","affiliation":[{"name":"Research, Development and Education Department, MALO CLINIC, Avenida dos Combatentes, 43, Level 10, 1600-042 Lisboa, Portugal"},{"name":"Cl\u00ednica Universit\u00e1ria de Estomatologia, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7801-454X","authenticated-orcid":false,"given":"Armando","family":"Lopes","sequence":"additional","affiliation":[{"name":"Oral Surgery Department, MALO CLINIC, Avenida dos Combatentes, 43, Level 9, 1600-042 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4495-4048","authenticated-orcid":false,"given":"Carolina","family":"Antunes","sequence":"additional","affiliation":[{"name":"Research, Development and Education Department, MALO CLINIC, Avenida dos Combatentes, 43, Level 10, 1600-042 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1095-8090","authenticated-orcid":false,"given":"Francisco","family":"Salvado","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Universit\u00e1ria de Estomatologia, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2025, October 22). 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