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Treatment is effective in the early stages. Thus, a need to screen considerable portions of the population is crucial. When the screening procedure uncovers a suspect lesion, a biopsy is performed to assess its potential for malignancy. This procedure is usually performed using real-time Ultrasound (US) imaging. This work proposes a visualization system for US breast biopsy. It consists of an application running on AR glasses that interact with a computer application. The AR glasses track the position of QR codes mounted on an US probe and a biopsy needle. US images are shown in the user\u2019s field of view with enhanced lesion visualization and needle trajectory. To validate the system, latency of the transmission of US images was evaluated. Usability assessment compared our proposed prototype with a traditional approach with different users. It showed that needle alignment was more precise, with 92.67 \u00b1 2.32\u00b0 in our prototype versus 89.99 \u00b1 37.49\u00b0 in a traditional system. The users also reached the lesion more accurately. Overall, the proposed solution presents promising results, and the use of AR glasses as a tracking and visualization device exhibited good performance.<\/jats:p>","DOI":"10.3390\/s23041838","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T02:04:16Z","timestamp":1675821856000},"page":"1838","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Augmented Reality-Assisted Ultrasound Breast Biopsy"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6195-5677","authenticated-orcid":false,"given":"Nuno","family":"Costa","sequence":"first","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"},{"name":"Algoritmi Center, School of Engineering, University of Minho, 4800-058 Guimaraes, Portugal"},{"name":"LASI\u2014Associate Laboratory of Intelligent Systems, 4800-058 Guimaraes, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9635-5372","authenticated-orcid":false,"given":"Lu\u00eds","family":"Ferreira","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9659-9609","authenticated-orcid":false,"given":"Augusto R. V. F.","family":"de Ara\u00fajo","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"},{"name":"Institute of Computing, Universidade Federal Fluminense (UFF), Niteroi 24210-310, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1616-2234","authenticated-orcid":false,"given":"Bruno","family":"Oliveira","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"},{"name":"Algoritmi Center, School of Engineering, University of Minho, 4800-058 Guimaraes, Portugal"},{"name":"LASI\u2014Associate Laboratory of Intelligent Systems, 4800-058 Guimaraes, Portugal"},{"name":"Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal"},{"name":"ICVS\/3B\u2019s\u2014PT Government Associate Laboratory, 4710-057 Braga\/Guimaraes, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8407-3255","authenticated-orcid":false,"given":"Helena R.","family":"Torres","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"},{"name":"Algoritmi Center, School of Engineering, University of Minho, 4800-058 Guimaraes, Portugal"},{"name":"LASI\u2014Associate Laboratory of Intelligent Systems, 4800-058 Guimaraes, Portugal"},{"name":"Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal"},{"name":"ICVS\/3B\u2019s\u2014PT Government Associate Laboratory, 4710-057 Braga\/Guimaraes, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1995-7879","authenticated-orcid":false,"given":"Pedro","family":"Morais","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1819-7051","authenticated-orcid":false,"given":"Victor","family":"Alves","sequence":"additional","affiliation":[{"name":"Algoritmi Center, School of Engineering, University of Minho, 4800-058 Guimaraes, Portugal"},{"name":"LASI\u2014Associate Laboratory of Intelligent Systems, 4800-058 Guimaraes, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4196-5357","authenticated-orcid":false,"given":"Jo\u00e3o L.","family":"Vila\u00e7a","sequence":"additional","affiliation":[{"name":"2Ai\u2014School of Technology, IPCA, 4750-810 Barcelos, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1002\/cac2.12207","article-title":"Global patterns of breast cancer incidence and mortality: A population-based cancer registry data analysis from 2000 to 2020","volume":"41","author":"Lei","year":"2021","journal-title":"Cancer Commun."},{"key":"ref_2","unstructured":"(2022, September 08). 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