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The research underscores the criticality of addressing technological, ethical, and practical hurdles in deploying these systems outside controlled laboratory environments. Methodologically, the study spanned three months and employed advanced facial recognition technology embedded in participants\u2019 computing devices to collect physiological metrics such as heart rate, blinking frequency, and emotional states, thereby contributing to a stress detection dataset. This approach ensured data privacy and aligns with ethical standards. The results reveal significant challenges in data collection and processing, including biases in video datasets, the need for high-resolution videos, and the complexities of maintaining data quality and consistency, with 42% (after adjustments) of data lost. In conclusion, this research emphasizes the necessity for rigorous, ethical, and technologically adapted methodologies to fully realize the benefits of these systems in diverse healthcare contexts.<\/jats:p>","DOI":"10.3390\/s25051357","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:36:47Z","timestamp":1740375407000},"page":"1357","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Overcoming Challenges in Video-Based Health Monitoring: Real-World Implementation, Ethics, and Data Considerations"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8233-2217","authenticated-orcid":false,"given":"Sim\u00e3o","family":"Ferreira","sequence":"first","affiliation":[{"name":"RISE-Health, Center for Translational Health and Medical Biotechnology Research (TBIO), ESS, Polytechnic of Porto, R. Dr. Ant\u00f3nio Bernardino de Almeida, 400, 4200-072 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8751-9339","authenticated-orcid":false,"given":"Catarina","family":"Marinheiro","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de Vila Nova de Gaia\/Espinho, 4430-999 Vila Nova de Gaia, Portugal"},{"name":"Faculdade de Ci\u00eancias da Sa\u00fade e Enfermagem, Universidade Cat\u00f3lica Portuguesa, 1649-023 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4472-5049","authenticated-orcid":false,"given":"Catarina","family":"Mateus","sequence":"additional","affiliation":[{"name":"RISE-Health, Center for Translational Health and Medical Biotechnology Research (TBIO), ESS, Polytechnic of Porto, R. 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