{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:12:04Z","timestamp":1767917524401,"version":"3.49.0"},"reference-count":45,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Separations"],"abstract":"<jats:p>The Calluna vulgaris honey produced in Portugal, concerning its phenolic compounds and abscisic acids profiles, as well as its antioxidant activity and the protective effect against oxidative damage in human erythrocytes were herein performed for the first time. The phenolic and abscisic acid profiles were tentatively identified by LC-MS\/MS (17 compounds). The total content of phenolics and abscisic acids was 15,446.4 \u00b5g\/g of honey extract, with catechin derivatives and abscisic acids being major constituents. The highest scavenging capacity was found against reactive nitrogen species. Additionally, the honey extract prevented ROO\u2022-induced oxidative damage in erythrocytes collected from human blood, by inhibiting hemolysis, lipid peroxidation and hemoglobin oxidation. In conclusion, C. vulgaris honey contains high content of catechin derivatives and abscisic acids that may be responsible for its biological activity, characterized by a strong antioxidant capacity, which adds up to the nutritional value of this delicacy.<\/jats:p>","DOI":"10.3390\/separations8100177","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T21:37:49Z","timestamp":1633901869000},"page":"177","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Chemical and Antioxidant Characterization of the Portuguese Heather Honey from Calluna vulgaris"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5264-3516","authenticated-orcid":false,"given":"Lu\u00eds","family":"Rodrigues da Silva","sequence":"first","affiliation":[{"name":"Center for Potential and Innovation of Natural Resources, CPIRN-UDI-IPG\u2013Research Unit for Inland Development, Polythecnic of Guarda, 6300-554 Guarda, Portugal"},{"name":"LAQV, REQUIMTE, Laborat\u00f3rio de Qu\u00edmica Aplicada, Departamento de Ci\u00eancias Qu\u00edmicas, Faculdade de Farm\u00e1cia, Universidade do Porto, 4050-313 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4549-3297","authenticated-orcid":false,"given":"Renan","family":"Campos Chist\u00e9","sequence":"additional","affiliation":[{"name":"LAQV, REQUIMTE, Laborat\u00f3rio de Qu\u00edmica Aplicada, Departamento de Ci\u00eancias Qu\u00edmicas, Faculdade de Farm\u00e1cia, Universidade do Porto, 4050-313 Porto, Portugal"},{"name":"Faculty of Food Engineering, Institute of Technology, Federal University of Par\u00e1 (UFPA), Bel\u00e9m 66075-110, PA, Brazil"}]},{"given":"Eduarda","family":"Fernandes","sequence":"additional","affiliation":[{"name":"LAQV, REQUIMTE, Laborat\u00f3rio de Qu\u00edmica Aplicada, Departamento de Ci\u00eancias Qu\u00edmicas, Faculdade de Farm\u00e1cia, Universidade do Porto, 4050-313 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"ref_1","first-page":"423","article-title":"Calluna vulgaris extract modulates NF-kappaB\/ERK signaling pathway and matrix metallo-proteinase expression in SKH-1 hairless mice skin exposed to ultraviolet B irradiation","volume":"63","author":"Filip","year":"2002","journal-title":"J. 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