{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:37:01Z","timestamp":1760229421817,"version":"build-2065373602"},"reference-count":57,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Swiss National Science Foundation","award":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"],"award-info":[{"award-number":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"]}]},{"name":"LARSyS\u2014Portuguese national funding agency for science, research and technology (FCT)","award":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"],"award-info":[{"award-number":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sustainability"],"abstract":"<jats:p>We aimed to examine associations between cognitive vulnerability and gait speed (GS) in a large older sample. A cross-sectional study analyzed data from the \u201cHealth, Lifestyle and Fitness in Adults and Seniors in Amazonas\u201d (SEVAAI) project. In total, 697 participants were included (mean age 70.35 \u00b1 6.86 years). Usual and fast GS were evaluated, and cognitive performance was examined by the COGTEL test battery. There was a positive and large correlation between cognition (COGTEL score) and usual GS (r = 0.510; p &lt; 0.001) and fast GS (r = 0.503; p &lt; 0.001). The usual GS, as a continuous variable, indicated a chance of improved cognitive performance by up to 55%, and fast GS by up to 82%. After controlling for potential confounders (i.e., sex, age, MMSE and years of education), usual and fast GS indicated a chance of improving cognition, respectively, in 57% and 85%. Analysis of GS in quartiles (Q) showed high and significant associations between usual and fast GS and cognitive vulnerability. GS classified as Q1 (slower), Q2 and Q3 represented a greater chance of presenting cognitive deficits, respectively, than in participants with both GS classified as Q4 (highest). Cognitive vulnerability was associated with low GS. Usual and fast GS can be used as complementary measures for the evaluation of cognitively normal Brazilian older adults.<\/jats:p>","DOI":"10.3390\/su14127348","type":"journal-article","created":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T21:19:26Z","timestamp":1655673566000},"page":"7348","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Gait Speed as a Biomarker of Cognitive Vulnerability: A Population-Based Study with Cognitively Normal Older Adults"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3577-3439","authenticated-orcid":false,"given":"Marcelo de Maio","family":"Nascimento","sequence":"first","affiliation":[{"name":"Department of Physical Education, Federal University of Vale do S\u00e3o Francisco, Petrolina 56304-917, Brazil"}]},{"given":"\u00c9lvio R\u00fabio","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, University of Madeira, 9020-105 Funchal, Portugal"},{"name":"LARSyS\u2014Laboratory for Robotics and Engineering Systems, Interactive Technologies Institute, 9020-105 Funchal, Portugal"},{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9850-7771","authenticated-orcid":false,"given":"Adilson","family":"Marques","sequence":"additional","affiliation":[{"name":"CIPER\u2014Interdisciplinary Centre for the Study of Human Performance, Faculty of Human Kinetics, University of Lisbon, 1495-751 Lisbon, Portugal"},{"name":"ISAMB\u2014Environmental Health Institute, Faculty of Medicine, University of Lisbon, 1649-020 Lisbon, Portugal"}]},{"given":"Bruna R.","family":"Gouveia","sequence":"additional","affiliation":[{"name":"LARSyS\u2014Laboratory for Robotics and Engineering Systems, Interactive Technologies Institute, 9020-105 Funchal, Portugal"},{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Regional Directorate of Health, Government of the Autonomous Region of Madeira, 9004-515 Funchal, Portugal"},{"name":"Saint Joseph of Cluny Higher School of Nursing, 9050-535 Funchal, Portugal"}]},{"given":"Priscila","family":"Marconcin","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, 1495-751 Lisbon, Portugal"},{"name":"KinesioLab, Research Unit in Human Movement Analysis, Piaget Institute, 2805-059 Almada, Portugal"}]},{"given":"Andreas","family":"Ihle","sequence":"additional","affiliation":[{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Department of Psychology, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Swiss National Centre of Competence in Research LIVES-Overcoming Vulnerability: Life Course Perspectives, 1015 Lausanne, Switzerland"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.archger.2017.07.023","article-title":"Slow gait speed is associated with executive function decline in older people with mild to moderate dementia: A one year longitudinal study","volume":"73","author":"Taylor","year":"2017","journal-title":"Arch. 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