{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T04:08:49Z","timestamp":1771042129331,"version":"3.50.1"},"reference-count":52,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T00:00:00Z","timestamp":1734825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"national funds through the Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/04625\/2020"],"award-info":[{"award-number":["UIDB\/04625\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sustainability"],"abstract":"<jats:p>Lean Six Sigma (LSS) is recognized as a powerful process improvement methodology for enhancing operational efficiency and long-term sustainability. This study examined the barriers hindering LSS implementation in the chemical process industry within an emerging economy, Brazil. It developed a structured methodology for designing mitigation measures to overcome those barriers. First, 26 barriers from the literature were ranked by LSS experts through a Delphi survey to select the top 15. Then, a combined interpretive structural modeling (ISM) approach and impact matrix cross-reference multiplication applied to a classification (MICMAC) analysis approach was used, supported by a focus group, to determine the hierarchical relationships among the barriers and their driving power and dependence. Finally, a second focus group defined adequate mitigation measures. The top four main barriers are the lack of time, insufficient systemic understanding of lean principles, misalignment between LSS and corporate strategies, and inadequate top management commitment. Additionally, 10 mitigation measures are proposed. This study contributes to LSS implementation in the chemical process industry in Brazil, thus enhancing industry sustainability by improving operational efficiency, curbing waste, reducing transportation-related emissions through a decreasing reliance on imported chemical products, and contributing to economic growth and job creation within the industry.<\/jats:p>","DOI":"10.3390\/su162411257","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T02:39:56Z","timestamp":1734921596000},"page":"11257","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Barriers to Implementing Lean Six Sigma in the Chemical Process Industry: The Case of Brazil"],"prefix":"10.3390","volume":"16","author":[{"given":"Caroline","family":"Tortorelli","sequence":"first","affiliation":[{"name":"Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1207-5854","authenticated-orcid":false,"given":"Am\u00edlcar","family":"Arantes","sequence":"additional","affiliation":[{"name":"CERIS, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1108\/JMTM-05-2013-0049","article-title":"Lean Implementation in Indian Process Industries\u2014Some Empirical Evidence","volume":"26","author":"Panwar","year":"2015","journal-title":"J. Manuf. Technol. Manag."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Alarc\u00f3n, F.J., Calero, M., P\u00e9rez-Huertas, S., and Mart\u00edn-Lara, M.\u00c1. (2023). State of the Art of Lean Six Sigma and Its Implementation in Chemical Manufacturing Industry Using a Bibliometric Perspective. Appl. 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