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Gender-Responsive Research and Innovation (GRRI) offers an approach to address this bias, promoting comprehensive and equitable solutions to better-understood real-world problems. The successful implementation of GRRI depends on recognizing obstacles, staying informed about relevant initiatives, and using this knowledge to develop effective strategies, ultimately contributing to a fairer and more responsive society. This research, using a mixed-methods approach, identified 10 critical GRRI concerns, measures, and strategies to address them, as well as 18 noteworthy initiatives across research, industrial, and regulatory contextual fields. It also enhances the understanding of GRRI, laying the groundwork for an ontology of GRRI that can benefit policymakers, organizations, and researchers seeking more inclusive strategies and practices.<\/jats:p>","DOI":"10.3390\/su17136215","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T08:58:23Z","timestamp":1751878703000},"page":"6215","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Gender-Responsive Research and Innovation: Issues and Initiatives"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0839-9250","authenticated-orcid":false,"given":"Sanaz","family":"Nikghadam-Hojjati","sequence":"first","affiliation":[{"name":"Center of Technology and Systems (UNINOVA-CTS), Associated Lab of Intelligent Systems (LASI), Department of Electrical and Computer Engineering, NOVA School of Science and Technology, NOVA University Lisbon, Institute of Information Science and Technologies \u201cAlessandro Faedo\u201d, National Research Council of Italy (CNR), 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4223-8036","authenticated-orcid":false,"given":"Eda","family":"Marchetti","sequence":"additional","affiliation":[{"name":"Institute of Information Science and Technologies \u201cAlessandro Faedo\u201d, National Research Council of Italy (CNR), Via G. 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