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Octocrylene (OC), an organic ultraviolet (UV) filter, and its breakdown product benzophenone (BP) are commonly found in aquatic environments, but their impact on keystone processes determining the success or failure of the early life stages of marine organisms remains underexplored. This study aims to assess the impacts of OC and BP at environmentally realistic concentrations (1, 10, and 100 \u00b5g.L\u22121), over a 24 h exposure period, on larvae of the Pacific oyster (Magallana gigas). A multiparametric approach was employed, examining DNA integrity, embryo\u2013larval development and swimming velocity. The results showed that DNA integrity and swimming velocity were not affected by OC or BP; however, both compounds increased developmental abnormalities in D-shaped larvae in all concentrations tested. Considering the robustness of morphological parameters, often assumed as irreversible, and their critical influence on larvae survival, these findings suggest that environmentally relevant concentrations of OC and BP may threaten the success of oyster larvae, potentially impacting the population\u2019s long-term stability and, ultimately, raising ecological health issues.<\/jats:p>","DOI":"10.3390\/toxics13030177","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T02:48:37Z","timestamp":1740710917000},"page":"177","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effects of the UV Filter Octocrylene and Its Degradation Product Benzophenone on Pacific Oyster (Magallana gigas) Larvae: A Call for Reassessment of Environmental Hazards"],"prefix":"10.3390","volume":"13","author":[{"given":"Ana","family":"Carvalhais","sequence":"first","affiliation":[{"name":"Centre for Environmental and Marine Studies (CESAM) and Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"Romina","family":"Lippa","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy"}]},{"given":"Isabel Benta","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, 4450-208 Matosinhos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3077-125X","authenticated-orcid":false,"given":"Gaetano","family":"Di Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Naples Federico II, Via Cinthia 26, 80126 Naples, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5539-2406","authenticated-orcid":false,"given":"Cl\u00e1udia","family":"Mieiro","sequence":"additional","affiliation":[{"name":"Centre for Environmental and Marine Studies (CESAM) and Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0552-9643","authenticated-orcid":false,"given":"M\u00e1rio","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Centre for Environmental and Marine Studies (CESAM) and Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3354\/ab00009","article-title":"Effects of increased seawater pCO2 on early development of the oyster Crassostrea gigas","volume":"1","author":"Kurihara","year":"2007","journal-title":"Aquat. 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