{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:04:50Z","timestamp":1760144690704,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"SexHealth and Prostate Cancer, Psychobiological Determinants of Sexual Health in Men in Prostate Cancer","award":["NORTE-01-0145-FEDER-000057"],"award-info":[{"award-number":["NORTE-01-0145-FEDER-000057"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Human papillomavirus (HPV) is the most prevalent sexually transmitted infection among young women. Notably, more than ten years after the introduction of HPV vaccination programs in Europe, it is essential to review the real-world evidence of the incidence of anogenital warts (GWs) among women vaccinated during childhood. In this systematic review, three databases were searched for studies published between January 2008 and September 2023. Nine cohort studies were included. A total of 890,320 HPV-vaccinated women and 1,922,033 unvaccinated women were evaluated. All the studies but one investigated the 4vHPV vaccine. The incidence rate of GWs in vaccinated women ranged from 0.0 to 1650 per 100,000 person-years. The highest incidence rates were found in women vaccinated with one dose at the age of 17\u201319 years old and in fully vaccinated women only after 19 years of age. Similar incidence values were reported among unvaccinated women. The incidence of GWs was lower when the age at first dose was 9\u201311 years old. This systematic review reveals that the incidence of GWs among HPV-vaccinated women is related to the age of vaccination and the number of vaccine doses received. In the post-vaccination era, epidemiological surveillance of the incidence of GWs and their genotypes is crucial.<\/jats:p>","DOI":"10.3390\/vaccines12050548","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T04:26:29Z","timestamp":1715919989000},"page":"548","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genital Warts in Women Vaccinated against HPV in Childhood: A Systematic Review"],"prefix":"10.3390","volume":"12","author":[{"given":"Renata","family":"Malheiro","sequence":"first","affiliation":[{"name":"Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3986-6253","authenticated-orcid":false,"given":"C\u00e9sar","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Gaia and Espinho Local Health Unit, 4434-502 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9356-3272","authenticated-orcid":false,"given":"Cl\u00e1udia Camila","family":"Dias","sequence":"additional","affiliation":[{"name":"Centre for Health Technology and Services Research\/Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"},{"name":"Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS) and Knowledge Management Unit, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"}]},{"given":"Ac\u00e1cio Gon\u00e7alves","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"},{"name":"Centre for Health Technology and Services Research\/Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8247-8902","authenticated-orcid":false,"given":"Carmen","family":"Lisboa","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"},{"name":"Centre for Health Technology and Services Research\/Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"},{"name":"Department of Dermatology and Venereology, University Hospital Center of S\u00e3o Jo\u00e3o, 4200-319 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,17]]},"reference":[{"key":"ref_1","unstructured":"Leslie, S.W., Sajjad, H., and Kumar, S. 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