{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:56:23Z","timestamp":1760147783894,"version":"build-2065373602"},"reference-count":69,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FCT","award":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"],"award-info":[{"award-number":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia, Portugal","award":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"],"award-info":[{"award-number":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"]}]},{"name":"Polish National Agency for Academic Exchange, Poland","award":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"],"award-info":[{"award-number":["UIDB\/00276\/2020","SFRH\/BD\/149758\/2019","UIDB\/00006\/2020","PPN\/ULM\/2020\/1\/00069\/U\/00001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>The teaching hospital of the Faculty of Veterinary Medicine at the University of Lisbon hosts a Biological Isolation and Containment Unit (BICU) for the hospitalization of both confirmed and suspected animals of an infectious disease. This study targets the BICU dog population to identify and characterize the most frequent infectious diseases recorded in a 7-year period. Several epidemiologic factors were analyzed for their significance to triage infected cases. During the study period, 534 dogs were admitted, of which 263 (49.3%) had a confirmed infectious disease diagnosis: parvovirosis (49.4%; n = 130); leptospirosis (21.7%; n = 57); multidrug-resistant (MDR) bacterial infection; (10.6%; n = 28), and canine distemper (9.9%; n = 26). Several potential risk factors for these diseases were identified: age under 2 years old (p &lt; 0.001), incomplete vaccination for parvovirosis (p &lt; 0.001), age \u2265 10 years old (p &lt; 0.001), and the presence of concomitant disorders for MDR-infected cases (p = 0.03). Logistic regression models were constructed to classify cases and controls. The sensitivity and specificity estimates were very high (&gt;0.83) for parvovirosis, MDR, and distemper infections. A lower sensitivity (0.77) was obtained for identifying cases with leptospirosis. In conclusion, infectious diseases are frequent, hence, it is essential to decrease their occurrence through effective preventive measures such as vaccination. The constructed logistic models can also help in triaging admitted dogs with a potential infectious disease.<\/jats:p>","DOI":"10.3390\/vetsci10030186","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T01:36:09Z","timestamp":1677634569000},"page":"186","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiologic Factors Supporting Triage of Infected Dog Patients Admitted to a Veterinary Hospital Biological Isolation and Containment Unit"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3815-1125","authenticated-orcid":false,"given":"In\u00eas Cunha","family":"Machado","sequence":"first","affiliation":[{"name":"Teaching Hospital, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"CIISA\u2014Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4388-5366","authenticated-orcid":false,"given":"Telmo","family":"Nunes","sequence":"additional","affiliation":[{"name":"CIISA\u2014Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3017-3178","authenticated-orcid":false,"given":"Miguel","family":"Maximino","sequence":"additional","affiliation":[{"name":"Teaching Hospital, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4389-1483","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Malato","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Molecular (IMM), Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Centro de Estat\u00edstica e Aplica\u00e7\u00f5es da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"given":"Lu\u00eds","family":"Tavares","sequence":"additional","affiliation":[{"name":"CIISA\u2014Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5902-132X","authenticated-orcid":false,"given":"Virgilio","family":"Almeida","sequence":"additional","affiliation":[{"name":"CIISA\u2014Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]},{"given":"Nuno","family":"Sep\u00falveda","sequence":"additional","affiliation":[{"name":"Centro de Estat\u00edstica e Aplica\u00e7\u00f5es da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"Faculty of Mathematics and Information Science, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9565-6261","authenticated-orcid":false,"given":"Solange","family":"Gil","sequence":"additional","affiliation":[{"name":"Teaching Hospital, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"CIISA\u2014Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Av. Universidade T\u00e9cnica, 1300-477 Lisboa, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, Av. Universidade T\u00e9cnica, 1300-477 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.2460\/javma.233.5.767","article-title":"Characteristics of Biosecurity and Infection Control Programs at Veterinary Teaching Hospitals","volume":"233","author":"Benedict","year":"2008","journal-title":"J. Am. Vet. Med. 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