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Inconsistent Relationships of Primary Consumer N Stable Isotope Values to Gradients of Sheep\/Beef Farming Intensity and Flow Reduction in Streams. Water, 11.","DOI":"10.3390\/w11112239"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Sanon, V., To\u00e9, P., Caballer Revenga, J., El Bilali, H., Hundscheid, L., Kulakowska, M., Magnuszewski, P., Meulenbroek, P., Paillaugue, J., and Sendzimir, J. (2020). Multiple-Line Identification of Socio-Ecological Stressors Affecting Aquatic Ecosystems in Semi-Arid Countries: Implications for Sustainable Management of Fisheries in Sub-Saharan Africa. Water, 12.","DOI":"10.3390\/w12061518"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Hughes, R., and Vadas, R. (2021). Agricultural Effects on Streams and Rivers: A Western USA Focus. 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