{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:33:32Z","timestamp":1788420812296,"version":"build-2803163510"},"reference-count":29,"publisher":"Royal College of General Practitioners","issue":"676","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Gen Pract"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of liver disease is increasing in the UK and primary care is a key setting where improvement in the detection and management of liver disease is required. Little is known about GPs\u2019 understanding and confidence in detecting liver disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To explore GPs\u2019 experiences of liver disease with a focus on early detection and interpretation of liver function tests (LFTs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and setting<\/jats:title><jats:p>A qualitative study employing semi-structured interviews of a purposive sample of GPs from five UK primary care study sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Telephone and face-to-face interviews of GPs were undertaken. Data were analysed thematically, using a constant comparative approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From a total of 25 GP interviews (<jats:italic>N<\/jats:italic>= 25), four themes were identified from the data: test-requesting behaviour, confidence and challenges in diagnosing disease, access to specialist tests, and guidance and education. Participants\u2019 descriptions of how they request and interpret LFTs varied widely. Concern over missing diagnoses was a common reason for requesting blood tests; patients with mildly abnormal LFTs and those at risk of non-alcoholic fatty liver disease (NAFLD) were a particular cause of concern. GPs saw themselves as generalists, with a reluctance to take on specialist investigations. Guidelines promoted confidence for some clinicians, but others felt that liver disease was too complex to be amenable to simple instructions. Most felt that they did not have access to relevant, focused education on liver disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Liver disease is not perceived as a priority in primary care. If GPs are to take on a greater role in identification and management of liver disease, support is needed to promote awareness, knowledge, and confidence.<\/jats:p><\/jats:sec>","DOI":"10.3399\/bjgp18x699377","type":"journal-article","created":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T23:24:31Z","timestamp":1537831471000},"page":"e743-e749","source":"Crossref","is-referenced-by-count":54,"title":["GPs\u2019 experiences and perceptions of early detection of liver disease: a qualitative study in primary care"],"prefix":"10.3399","volume":"68","author":[{"given":"Holly C","family":"Standing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Jarvis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Orr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Exley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"Kaner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Hanratty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1987","published-online":{"date-parts":[[2018,9,24]]},"reference":[{"key":"2020081209323813000_68.676.e743.1","unstructured":"World Health Organization WHO European Health for All database, http:\/\/www.euro.who.int\/en\/data-and-evidence\/databases\/european-health-for-all-family-of-databases-hfa-db (accessed 14 Sep 2018)."},{"key":"2020081209323813000_68.676.e743.2","unstructured":"Public Health England. 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