{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:56:21Z","timestamp":1789232181029,"version":"build-2803163510"},"reference-count":46,"publisher":"Royal College of General Practitioners","issue":"687","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Gen Pract"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the importance of secondary prevention after transient ischaemic attack (TIA) or minor stroke is recognised, research is sparse regarding novel, effective ways in which to intervene in a primary care context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      To pilot a randomised controlled trial (RCT) of a novel home-based prevention programme (\n                      <jats:italic>The Healthy Brain Rehabilitation Manual<\/jats:italic>\n                      ) for patients with TIA or \u2018minor\u2019 stroke.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and setting<\/jats:title>\n                    <jats:p>Pilot RCT, home-based, undertaken in Northern Ireland between May 2017 and March 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Patients within 4 weeks of a first TIA or \u2018minor\u2019 stroke received study information from clinicians in four hospitals. Participants were randomly allocated to one of three groups: standard care (control group) (\n                      <jats:italic>n<\/jats:italic>\n                      = 12); standard care with manual and GP follow-up (\n                      <jats:italic>n<\/jats:italic>\n                      = 14); or standard care with manual and stroke nurse follow-up (\n                      <jats:italic>n<\/jats:italic>\n                      = 14). Patients in all groups received telephone follow-up at 1, 4, and 9 weeks. Eligibility, recruitment, and retention were assessed; stroke\/cardiovascular risk factors measured at baseline and 12 weeks; and participants\u2019 views were elicited about the study via focus groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Over a 32-week period, 28.2% of clinic attendees (125\/443) were eligible; 35.2% of whom (44\/125) consented to research contact; 90.9% of these patients (40\/44) participated, of whom 97.5% (39\/40) completed the study. After 12 weeks, stroke risk factors [cardiovascular risk factors, including blood pressure and measures of physical activity] improved in both intervention groups. The research methods and the programme were acceptable to patients and health professionals, who commented that the programme \u2018filled a gap\u2019 in current post-TIA management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Findings indicate that implementation of this novel cardiac rehabilitation programme, and of a trial to evaluate its effectiveness, is feasible, with potential for clinically important benefits and improved secondary prevention after TIA or \u2018minor\u2019 stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3399\/bjgp19x705509","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:24:14Z","timestamp":1568075054000},"page":"e706-e714","source":"Crossref","is-referenced-by-count":24,"title":["Rehabilitation of patients after transient ischaemic attack or minor stroke: pilot feasibility randomised trial of a home-based prevention programme"],"prefix":"10.3399","volume":"69","author":[{"given":"Neil","family":"Heron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Kee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Mant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret E","family":"Cupples","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1987","published-online":{"date-parts":[[2019,9,9]]},"reference":[{"key":"2020081209340538000_69.687.e706.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61448-2"},{"key":"2020081209340538000_69.687.e706.2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.129163"},{"key":"2020081209340538000_69.687.e706.3","doi-asserted-by":"crossref","unstructured":"Murphy E Vellinga A Byrne M (2015) Br J Gen Pract, Primary care organisational interventions for secondary prevention of ischaemic heart disease: a systematic review and meta-analysis. 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