{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:38:29Z","timestamp":1787168309274,"version":"build-2736575974"},"reference-count":52,"publisher":"Royal College of General Practitioners","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJGP Open"],"accepted":{"date-parts":[[2026,1,22]]},"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Prostate-specific antigen (PSA)-based prostate cancer (PCa) screening risks overdiagnosis and overtreatment. PCa disproportionately affects Black men, those with a family history (FH) of the disease, and\n                      <jats:italic>BRCA1\/2<\/jats:italic>\n                      gene variant carriers. Risk-adapted approaches are gaining interest but are underexplored.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess the feasibility of PSA-based Targeted Prostate Health Checks (TPHCs) for men at high PCa risk, compare invitation methods, and assess sociodemographic variations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design &amp; setting<\/jats:title>\n                    <jats:p>Prospective feasibility cohort study in four primary care networks (PCNs) in North East London.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Men aged 45\u201369 years from Black ethnic group, or with a positive PCa FH, were identified via primary care records and invited by the PCN to one of two TPHCs: (i) telephone-first (phone consultation followed by hospital-based PSA testing); or (ii) test-first (community-based PSA testing followed by phone consultation). Elevated PSA prompted multiparametric magnetic resonance imaging (mpMRI), and prostate biopsy if malignancy was suspected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2400 invitees, 398 (16.6%) attended. Attendance was higher with the test-first than telephone-first TPHC (22.9% versus 11.2%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). Only 51.4% of participants met eligibility criteria owing to inaccurate FH coding, although men who did not meet the eligibility criteria were offered PSA tests. Black men had lower prior PSA testing (55.7% versus 82.5%) and higher deprivation than White men. Elevated PSA occurred in 6.0% of participants (\n                      <jats:italic>n<\/jats:italic>\n                      = 22), with five PCa diagnoses (1.4%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Identification of men at high PCa risk is feasible using age and ethnicity primary care data, but FH coding is unreliable. Test-first invitations improved engagement. Disparities affecting Black men highlight the need for tailored outreach, and better coding of risk factors will facilitate risk-adapted screening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3399\/bjgpo.2025.0219","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:50:16Z","timestamp":1781657416000},"page":"BJGPO.2025.0219","source":"Crossref","is-referenced-by-count":0,"title":["Targeted Prostate Health Checks for prostate cancer in men at high risk: a feasibility pilot in primary and secondary care in North East London"],"prefix":"10.3399","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8085-0555","authenticated-orcid":false,"given":"Muhammad","family":"Haider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apple","family":"Dumagat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James SA","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Allchorne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela S","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Ashraf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopal","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwabunmi","family":"Olajide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhian","family":"Gabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona M","family":"Walter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stafford","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Paparini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin W","family":"Lamb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhakar","family":"Rajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the North East London Cancer Alliance Targeted Prostate Health Check Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1987","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"2026081911351718000_10.2.BJGPO.2025.0219.1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29538"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.3","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-015-0405-5"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.4","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.383"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.5","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-0370"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.6","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2014.35"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.02.009"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.8","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30474"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.4011"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.10","unstructured":"UK National Screening Committee (2026) Adult screening programme. Prostate cancer. accessed. https:\/\/view-health-screening-recommendations.service.gov.uk\/prostate-cancer\/. 10 Jun 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.11","unstructured":"National Institute for Health and Care Excellence (NICE) (2023) Suspected cancer: recognition and referral [NICE guideline NG12]. accessed. https:\/\/www.nice.org.uk\/guidance\/ng12. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.12","unstructured":"NICE (2026) How should I assess a person with suspected prostate cancer? accessed. https:\/\/cks.nice.org.uk\/topics\/prostate-cancer\/diagnosis\/assessment\/. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.13","unstructured":"Public Health England (2016) Prostate cancer risk management programme: overview. accessed. .. https:\/\/www.gov.uk\/guidance\/prostate-cancer-risk-management-programme-overview. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.14","unstructured":"NHS England (2022) Implementing a timed prostate cancer diagnostic pathway Guidance for local health and care systems. accessed. https:\/\/www.england.nhs.uk\/wp-content\/uploads\/2018\/04\/B1348_Prostate-cancer-timed-diagnostic-pathway.pdf. 10 Jun 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.02.047"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.16","doi-asserted-by":"publisher","DOI":"10.1136\/bmjonc-2024-000643"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.17","doi-asserted-by":"publisher","DOI":"10.1177\/2051415815594976"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjmsu.2011.07.003"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.19","unstructured":"National Prostate Cancer Audit (2025) State of the Nation Report. accessed. https:\/\/www.natcan.org.uk\/reports\/npca-state-of-the-nation-report-2025. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.20","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-023-00828-w"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.21","doi-asserted-by":"publisher","DOI":"10.1002\/tre.12003"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.22","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-016-0137-7"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.23","unstructured":"Prostate Cancer Research (2024) Socio-economic impact of prostate cancer screening. accessed. .. https:\/\/www.prostate-cancer-research.org.uk\/wp-content\/uploads\/2024\/11\/PCR_Socioeconomic_Impact_Prostate_Cancer_Screening_Nov24-v1.0.pdf. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.24","doi-asserted-by":"publisher","DOI":"10.3399\/BJGP.2023.0586"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.25","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.15.1310"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.08.019"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.27","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.17703"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.28","unstructured":"Hunter Healthcare (2024) Two non-executive members: finance & peformance and clinical & care professional candidate information pack, accessed. https:\/\/www.england.nhs.uk\/non-executive-opportunities\/wp-content\/uploads\/sites\/54\/2024\/02\/NEL_ICB_INEM_Pack-1-1.pdf. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.29","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03283-5"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08940.x"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.31","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.495"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.32","doi-asserted-by":"publisher","DOI":"10.1111\/ijun.12199"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.33","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.416"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.34","doi-asserted-by":"publisher","DOI":"10.1016\/S1462-3889(14)70037-7"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.35","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.35169"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.36","unstructured":"Cornford P Tilki D van den Bergh RCN et al (2025) EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on prostate cancer, accessed. https:\/\/uroweb.org\/guidelines\/prostate-cancer. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.37","unstructured":"Getting it Right First Time (GRIFT) NHS England (2024) GIRFT urology: towards better diagnosis & management of suspected prostate cancer. accessed. .. https:\/\/gettingitrightfirsttime.co.uk\/wp-content\/uploads\/2024\/04\/GIRFT-Urology-Towards-Better-Diagnosis-Management-of-Suspected-Prostate-Cancer-FINAL-V1-April-2024-1.pdf. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.38","unstructured":"British Association of Urological Surgeons (BAUS) (2026) International prostate symptom score (I-PSS). accessed. https:\/\/www.baus.org.uk\/patients\/information_leaflets\/116\/international_prostate_symptom_score_ipss. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.39","unstructured":"Ministry of Housing, Communities & Local Government (2019) The English Indices of Deprivation 2019. accessed. https:\/\/www.gov.uk\/government\/statistics\/english-indices-of-deprivation-2019. 10 Jun 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.40","doi-asserted-by":"publisher","DOI":"10.1177\/1557988307312784"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.41","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2025.10.007"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.42","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.0154"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.43","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-016-1624-6"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.44","unstructured":"Transformation Partners in Health and Care (2021) Children and young people\u2019s mental health inequalities ICS data snapshots: North East London (NEL) (Transformation Partners in Health and Care, London)."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.45","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.04.044"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.46","unstructured":"Ream E Finnegan-John J Pedersen VH (2012) Evaluation of a community-based prostate health clinic in London (King\u2019s College London, London)."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.47","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmab117"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.48","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp20X713957"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.49","unstructured":"NICE (2023) Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer [Clinical guideline CG164], accessed. https:\/\/www.nice.org.uk\/guidance\/cg164. 2 Apr 2026."},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.50","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-020-00783-9"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.51","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03499-5"},{"key":"2026081911351718000_10.2.BJGPO.2025.0219.52","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5239"}],"container-title":["BJGP Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3399\/BJGPO.2025.0219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:35:48Z","timestamp":1787164548000},"score":1,"resource":{"primary":{"URL":"http:\/\/bjgpopen.org\/lookup\/doi\/10.3399\/BJGPO.2025.0219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,16]]},"references-count":52,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,8,19]]},"published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.3399\/BJGPO.2025.0219"],"URL":"https:\/\/doi.org\/10.3399\/bjgpo.2025.0219","relation":{},"ISSN":["2398-3795"],"issn-type":[{"value":"2398-3795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,16]]}}}