{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T17:43:13Z","timestamp":1700761393039},"reference-count":14,"publisher":"Royal College of General Practitioners","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJGP Open"],"published-print":{"date-parts":[[2019,7]]},"abstract":"Background<\/jats:title>Over 75% of patients (approximately half a million) with coeliac disease in the UK have not been formally diagnosed.<\/jats:p><\/jats:sec>Aim<\/jats:title>To determine if case-finding of coeliac disease is better than random testing in primary care.<\/jats:p><\/jats:sec>Design & setting<\/jats:title>A pragmatic study looked at all referrals across a 12-month period (December 2013\u2013November 2014) for coeliac serology testing and the indications for testing across 38 GP practices in a well-defined geographical area in North Yorkshire. There was further follow-up for an additional 12 months to determine conversion of positive serology to duodenal biopsy.<\/jats:p><\/jats:sec>Method<\/jats:title>All serology samples sent into York Hospital biochemistry department during the study period were analysed for the indication for testing. Positive results were cross-referenced for duodenal biopsies over the following 12 months on the York Hospital pathology database.<\/jats:p><\/jats:sec>Results<\/jats:title>Case-finding of coeliac patients in primary care is no better than random testing of the population. Only 71% of patients with positive serology went on to have a duodenal biopsy in the following 12 months.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>More education of the population and of primary care physicians is needed around the indications for checking for coeliac disease. It may be that primary care is not the best place to case-find patients with coeliac disease.<\/jats:p><\/jats:sec>","DOI":"10.3399\/bjgpopen19x101648","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T04:55:08Z","timestamp":1561524908000},"page":"bjgpopen19X101648","source":"Crossref","is-referenced-by-count":1,"title":["Determining whether coeliac disease case-finding in primary care is better than random testing: a retrospective study"],"prefix":"10.3399","volume":"3","author":[{"given":"Kim","family":"Chandler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerry","family":"Robins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1987","published-online":{"date-parts":[[2019,6,25]]},"reference":[{"key":"2020081209181430000_3.2.bjgpopen19X101648.1","unstructured":"NHS England (2015) Using case finding and risk stratification: a key service component for personalised care and support planning. https:\/\/www.england.nhs.uk\/wp-content\/.\/01\/2015-01-20-CFRS-v0.14-FINAL.pdf. 5 Jun 2019."},{"key":"2020081209181430000_3.2.bjgpopen19X101648.2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-306578"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.3","unstructured":"National Institute for Health and Care Excellence (2009) Coeliac disease recognition and assessment of coeliac disease [NICE Clinical Guideline No 86] (NICE, London), 1\u201323."},{"key":"2020081209181430000_3.2.bjgpopen19X101648.4","unstructured":"National Institute for Health and Care Excellence (2015) Coeliac disease: recognition, assessment and management [NICE Clinical Guideline No 20]. https:\/\/www.nice.org.uk\/guidance\/ng20\/resources\/coeliac-disease-recognition-assessment-and-management-pdf-1837325178565. 22 May 2019."},{"key":"2020081209181430000_3.2.bjgpopen19X101648.5","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301346"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.6","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e32831ef20d"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.7","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.55"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.8","unstructured":"Coeliac UK Our campaign successes. https:\/\/www.coeliac.org.uk\/campaigns-and-research\/our-campaign-successes\/. 22 May 2019."},{"key":"2020081209181430000_3.2.bjgpopen19X101648.9","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2014.869996"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i40.7201"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.11","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000962"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.12","doi-asserted-by":"publisher","DOI":"10.1177\/2050640618761700"},{"issue":"541","key":"2020081209181430000_3.2.bjgpopen19X101648.13","first-page":"636","article-title":"A case-control study of presentations in general practice before diagnosis of coeliac disease","volume":"57","author":"Cannings-John","year":"2007","journal-title":"Br J Gen Pract"},{"key":"2020081209181430000_3.2.bjgpopen19X101648.14","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31821a23d0"}],"container-title":["BJGP Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3399\/bjgpopen19X101648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T16:28:50Z","timestamp":1597249730000},"score":1,"resource":{"primary":{"URL":"http:\/\/bjgpopen.org\/lookup\/doi\/10.3399\/bjgpopen19X101648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,25]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,7,23]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.3399\/bjgpopen19X101648"],"URL":"https:\/\/doi.org\/10.3399\/bjgpopen19x101648","relation":{},"ISSN":["2398-3795"],"issn-type":[{"value":"2398-3795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,25]]}}}