{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:08:22Z","timestamp":1790525302233,"version":"4.1.0"},"reference-count":34,"publisher":"Royal College of General Practitioners","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJGP Open"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The use of potentially inappropriate medications (PIMs) is an important issue in older patients who are at risk of adverse drug events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the prevalence of PIM use, according to Beers criteria, among an older population (aged \u226565 years) in a large family medicine setting, and to identify the associated risks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design &amp; setting<\/jats:title><jats:p>A prospective cross-sectional study of patients aged \u226565 years was conducted from June 2017 to June 2018 at the Family and Community Medicine (FCM) clinics of King Saud Medical City (KSMC) in Riyadh, Saudi Arabia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This cross-sectional study included patients aged \u226565 years who were seen at new appointments or followed-up at the FCM clinics of KSMC in Riyadh, Saudi Arabia. Data were collected by extensive face-to-face interviews and from the patients\u2019 medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 270 older patients aged 72.41 \u00b16.23 years (mean \u00b1standard deviation [SD]) were included in the present study. The prevalence of PIMs was 60.7% (<jats:italic>n<\/jats:italic> = 164). Multivariate analyses identified three independent variables associated with PIMs: incremental age per 5 years (odds ratio [OR] 1.47, 95% confidence intervals [CI] = 1.15 to 1.88; <jats:italic>P<\/jats:italic> = 0.002), female sex (OR 1.95, 95% CI = 1.10 to 3.42; <jats:italic>P<\/jats:italic> = 0.021), and polypharmacy (OR 8.21, 95% CI = 4.58 to 14.7; <jats:italic>P<\/jats:italic>&lt;0.001). The most common PIMs used were 39.4% related to proton pump inhibitors (PPI), 25.2% to diuretics (other than spironolactone), 10.6% to non-steroidal anti-inflammatory drugs (NSAIDs), and 8.7% to aspirin use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed high prevalence of PIMs. Increasing age, female sex, and polypharmacy were found to be significant risk factors for PIM use. The frequency of morbidities was not significantly different among patients with PIMs compared to those without PIMs, except for hypertension and osteoarthritis, which were more common in the PIMs group. The present study reinforces the importance of comprehensive medication management and reviews.<\/jats:p><\/jats:sec>","DOI":"10.3399\/bjgpopen20x101009","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T05:45:16Z","timestamp":1580881516000},"page":"bjgpopen20X101009","source":"Crossref","is-referenced-by-count":34,"title":["Potentially inappropriate medications in older patients based on Beers criteria: a cross-sectional study of a family medicine practice in Saudi Arabia"],"prefix":"10.3399","volume":"4","author":[{"given":"Atheer","family":"Alturki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tareef","family":"Alaama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousef","family":"Alomran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Al-Jedai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajer","family":"Almudaiheem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1559-6930","authenticated-orcid":false,"given":"Ghassan","family":"Watfa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1987","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"2020081209184389000_4.1.bjgpopen20X101009.1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.19006"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.1.68"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.3","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2005.11.7.575"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.4","doi-asserted-by":"publisher","DOI":"10.3928\/0098-9134-20050901-04"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.5","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.2016.37.6.329"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.6","doi-asserted-by":"publisher","DOI":"10.1007\/s40801-015-0035-4"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2016.05.006"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.8","doi-asserted-by":"publisher","DOI":"10.1177\/2333721416637790"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.9","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13702."},{"key":"2020081209184389000_4.1.bjgpopen20X101009.10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008165.pub2"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.11","unstructured":"United Nations Economic and Social Commission for Western Asia (2017) The demographic profile of Saudi Arabia. 8 Jan 2020. https:\/\/www.unescwa.org\/sites\/www.unescwa.org\/files\/saudi_arabia_2017-single_pages_jan_5.pdf."},{"key":"2020081209184389000_4.1.bjgpopen20X101009.12","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20150131"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.13","doi-asserted-by":"publisher","DOI":"10.1186\/s12875-016-0482-3"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.14","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.12212"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094350"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.16","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-013-0337-8"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.17","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0258(20010130)20:2&lt;324::AID-SIM635&gt;3.0.CO;2-O"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-9-30"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0594.2012.00951.x"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.20","unstructured":"General Authority for Statistics (2017) Elderly survey 8 Jan 2020. https:\/\/www.stats.gov.sa\/sites\/default\/files\/elderly_survey_2017en.pdf."},{"key":"2020081209184389000_4.1.bjgpopen20X101009.21","doi-asserted-by":"publisher","DOI":"10.3390\/geriatrics4020036"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2009.03.001"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.23","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.172558"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.24","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2001.119456"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.25","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S2468"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.26","doi-asserted-by":"publisher","DOI":"10.1186\/1865-1380-4-22"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.27","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-012-9656-9"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.28","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-200522010-00005"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.29","doi-asserted-by":"publisher","DOI":"10.5414\/CP201441"},{"issue":"11","key":"2020081209184389000_4.1.bjgpopen20X101009.30","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.18203\/2319-2003.ijbcp20174768","article-title":"A prospective observational study of prescription appropriateness of elderly hypertensive patients using Beers criteria in a tertiary care teaching hospital","volume":"6","author":"Supriya","year":"2017","journal-title":"International Journal of Basic & Clinical Pharmacology"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1996.tb03729.x"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.32","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1001458"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088272"},{"key":"2020081209184389000_4.1.bjgpopen20X101009.34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04874.x"}],"container-title":["BJGP Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3399\/bjgpopen20X101009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T16:35:41Z","timestamp":1597250141000},"score":1,"resource":{"primary":{"URL":"http:\/\/bjgpopen.org\/lookup\/doi\/10.3399\/bjgpopen20X101009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,4]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,5,1]]},"published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.3399\/bjgpopen20X101009"],"URL":"https:\/\/doi.org\/10.3399\/bjgpopen20x101009","relation":{},"ISSN":["2398-3795"],"issn-type":[{"value":"2398-3795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,4]]}}}