{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:30:39Z","timestamp":1790688639251,"version":"4.1.0"},"reference-count":75,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Hemodialysis is an intensive treatment with a substantial time burden for patients. Generally, a standard hemodialysis schedule consists of three treatments per week, each lasting 4 hours. However, it can be debated whether this schedule is appropriate for all patients. Incremental hemodialysis refers to a treatment approach where hemodialysis is initiated with a less intensive schedule (\n                    <jats:italic toggle=\"yes\">i.e<\/jats:italic>\n                    ., fewer sessions per week) and gradually increased as residual kidney function declines. The effects of incremental hemodialysis on key outcomes\u2014health-related quality of life, vascular access-related complications, and fluid overload\u2014were discussed in this review. Although incremental hemodialysis is hypothesized to improve health-related quality of life, most studies found no significant difference. Similarly, most studies did not report significant differences in vascular access-related complications. Concerns have been raised regarding fluid overload due to extended intervals between sessions and underdialysis, especially when the transition to a thrice-weekly schedule is delayed. However, most studies found no difference in fluid overload related outcomes. Incremental hemodialysis is a promising, personalized treatment that could reduce the socioeconomic burden of dialysis. Given the methodologic limitations of available studies, ongoing trials will contribute to a clearer understanding of the role of incremental hemodialysis with varying residual kidney function at initiation.\n                  <\/jats:p>","DOI":"10.34067\/kid.0000001017","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T18:02:34Z","timestamp":1762970554000},"page":"435-444","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Perspectives on Quality of Life, Vascular Access, and Fluid Balance in Incremental Hemodialysis"],"prefix":"10.34067","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7225-8542","authenticated-orcid":false,"given":"Sanne","family":"Roos","sequence":"first","affiliation":[{"name":"Department of Nephrology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"},{"name":"Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1628-2503","authenticated-orcid":false,"given":"Thomas S.","family":"van Lieshout","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"},{"name":"Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alferso C.","family":"Abrahams","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigit C.","family":"van Jaarsveld","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8079-0166","authenticated-orcid":false,"given":"Frans J.","family":"van Ittersum","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6018-4679","authenticated-orcid":false,"given":"Erik L.","family":"Penne","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"issue":"suppl 2","key":"B1-20260226","first-page":"ii5","article-title":"EBPG guideline on dialysis strategies","volume":"22","author":"Tattersall","year":"2007","journal-title":"Nephrol Dial Transplant."},{"issue":"1 suppl 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