{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:32:03Z","timestamp":1786480323033,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2026,3]]},"abstract":"\n Key Points<\/jats:title>\n \n \n \n Health care utilization rates in elderly kidney transplant were no different between the high kidney donor profile index and low kidney donor profile index group.<\/jats:p>\n <\/jats:list-item>\n \n Number of readmissions and surgical interventions in elderly kidney transplant was no different between the high kidney donor profile index and low kidney donor profile index group.<\/jats:p>\n <\/jats:list-item>\n \n Death censored graft loss was higher in the high kidney donor profile index group, whereas the patient survival was no different between the high kidney donor profile index and low kidney donor profile index groups.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n High kidney donor profile index (KDPI) kidneys (KDPI >85%) are often associated with increased risks of post-kidney transplant (KT) complications and greater health care utilization (HCU), particularly in elderly recipients with multiple comorbidities. These concerns frequently lead to underutilization of high KDPI kidneys in older transplant candidates, thereby limiting their access to transplantation despite potential clinical benefits. The aim of this study was to compare post-KT HCU between elderly recipients of high versus low KDPI deceased donor kidneys. The primary outcome included differences in hospital readmissions, surgical interventions, and outpatient service use at multiple post-transplant time points. Secondary outcome included graft function, graft survival, and patient survival.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective analysis of elderly solitary KT recipients (age \u226565 years) between January 1, 2011, and December 31, 2020. Patients were stratified into high KDPI (>85%,\n n<\/jats:italic>\n =160) and low KDPI (\u226485%,\n n<\/jats:italic>\n =453) groups. We assessed inpatient and outpatient HCU, including readmissions at 30, 90, and 365 days post-transplant, surgical interventions, and outpatient visits (emergency department, transplant clinic, endocrine clinic, and ambulatory infusion units).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were no statistically significant differences between high and low KDPI groups in rates of hospital readmissions, surgical interventions, or outpatient visits (all\n P<\/jats:italic>\n > 0.05). Delayed graft function rates were also similar (\n P<\/jats:italic>\n = 0.61). The low KDPI group had significantly higher eGFR at 4 months, 1, 2, and 3 years post-transplant (all\n P<\/jats:italic>\n < 0.001). However, days alive and out of the hospital within 90 and 365 days post-transplant were comparable between the groups (all\n P<\/jats:italic>\n > 0.05). Overall patient survival was similar (\n P<\/jats:italic>\n = 0.08), although death-censored graft loss was significantly higher in the high KDPI group (\n P<\/jats:italic>\n = 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Among elderly KT recipients, high KDPI kidney recipients had comparable post-transplant HCU and overall survival with those receiving low KDPI kidneys, despite lower long-term graft function. These findings suggest that high KDPI kidneys remain a viable option for older patients, offering timely access to transplantation.<\/jats:p>\n <\/jats:sec>","DOI":"10.34067\/kid.0000001028","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T17:01:47Z","timestamp":1764954107000},"page":"642-652","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Health Care Utilization in Elderly Deceased Donor Kidney Transplant Recipients"],"prefix":"10.34067","volume":"7","author":[{"given":"Rachana","family":"Punukollu","sequence":"first","affiliation":[{"name":"Division of Nephrology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hui","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumi S.","family":"Nair","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4141-7243","authenticated-orcid":false,"given":"Lavanya","family":"Kodali","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1530-6665","authenticated-orcid":false,"given":"Bassam G.","family":"Abu Jawdeh","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9215-2014","authenticated-orcid":false,"given":"Amit K.","family":"Mathur","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3764-0047","authenticated-orcid":false,"given":"Girish","family":"Mour","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"issue":"2","key":"B3-20260330","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/TP.0b013e3181ac620b","article-title":"A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index","volume":"88","author":"Rao","year":"2009","journal-title":"Transplantation."},{"issue":"4","key":"B5-20260330","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1097\/TP.0000000000001405","article-title":"Survival benefit in older patients associated with earlier transplant with high KDPI kidneys","volume":"101","author":"Jay","year":"2017","journal-title":"Transplantation."},{"issue":"4","key":"B6-20260330","doi-asserted-by":"crossref","first-page":"102","DOI":"10.5500\/wjt.v8.i4.102","article-title":"Kidney transplantation in older recipients: preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage","volume":"8","author":"Chopra","year":"2018","journal-title":"World J Transplant."},{"issue":"12","key":"B7-20260330","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1111\/tri.13483","article-title":"Functional status-based risk-benefit analyses of high-KDPI kidney transplant versus dialysis","volume":"32","author":"Bui","year":"2019","journal-title":"Transpl Int."},{"issue":"10","key":"B8-20260330","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1111\/ajt.12830","article-title":"Survival benefit of primary deceased donor transplantation with high-KDPI kidneys","volume":"14","author":"Massie","year":"2014","journal-title":"Am J 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Organ Transplant."},{"issue":"6","key":"B28-20260330","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.ekir.2024.04.067","article-title":"Can future value-based care models in nephrology promote kidney transplantation?","volume":"9","author":"Jain","year":"2024","journal-title":"Kidney Int Rep."}],"container-title":["Kidney360"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0000001028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:03:40Z","timestamp":1786478620000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0000001028"}},"subtitle":["Does Kidney Donor Profile Index Matter?"],"short-title":[],"issued":{"date-parts":[[2025,12,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.34067\/kid.0000001028","relation":{},"ISSN":["2641-7650"],"issn-type":[{"value":"2641-7650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,5]]},"assertion":[{"value":"2025-06-02","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}