{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:29:45Z","timestamp":1786480185004,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      We report the case of a 23-year-old woman who developed minimal change disease (MCD) in the\n                      <jats:italic toggle=\"yes\">postpartum<\/jats:italic>\n                      period. Kidney biopsy findings were consistent with MCD, with positive anti-nephrin immunostaining. Her clinical course was complicated by multiple relapses and steroid intolerance, requiring treatment with multiple immunosuppressive therapies. Despite therapy, complete remission was not achieved. A year and a half after the MCD diagnosis, she was diagnosed with Hodgkin lymphoma. After chemotherapy and radiation therapy, the patient finally achieved complete remission of both MCD and Hodgkin lymphoma. This case highlights the complex relationship between MCD and lymphoproliferative disorders. It suggests that anti-nephrin positive MCD, typically considered a primary podocytopathy, may in rare instances represent a paraneoplastic manifestation. In addition, this report highlights the importance of maintaining a high index of suspicion for occult malignancy in young patients with relapsing or refractory MCD, despite biomarkers suggesting primary disease.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.34067\/kid.0000001225","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T16:02:36Z","timestamp":1776700956000},"page":"1651-1654","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["When the Podocyte Speaks First"],"prefix":"10.34067","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2372-8064","authenticated-orcid":false,"given":"Krishna Mohita","family":"Kuruvada","sequence":"first","affiliation":[{"name":"Division of Kidney Diseases and Hypertension, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Great Neck, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fady","family":"Gries","sequence":"additional","affiliation":[{"name":"Division of Kidney Diseases and Hypertension, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Great Neck, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Wanchoo","sequence":"additional","affiliation":[{"name":"Manhasset Secondary Schools, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Great Neck, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1633-0245","authenticated-orcid":false,"given":"Astrid","family":"Weins","sequence":"additional","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1578-0524","authenticated-orcid":false,"given":"Kenar D.","family":"Jhaveri","sequence":"additional","affiliation":[{"name":"Division of Kidney Diseases and Hypertension, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Great Neck, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"issue":"12","key":"B1-20260731","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1038\/sj.ki.5000341","article-title":"Minimal change nephrotic syndrome and classical hodgkin lymphoma: report of 21 cases and review of the literature","volume":"69","author":"Audard","year":"2006","journal-title":"Kidney Int."},{"issue":"1","key":"B2-20260731","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1681\/ASN.2021060794","article-title":"Discovery of autoantibodies targeting Nephrin in minimal change disease supports a novel autoimmune etiology","volume":"33","author":"Watts","year":"2022","journal-title":"J Am Soc Nephrol."},{"issue":"3","key":"B3-20260731","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/ndt\/6.3.155","article-title":"Minimal change nephrotic syndrome associated with Hodgkin\u2019s lymphoma","volume":"6","author":"Peces","year":"1991","journal-title":"Nephrol Dial Transplant."},{"issue":"3","key":"B4-20260731","doi-asserted-by":"crossref","first-page":"228","DOI":"10.5414\/CNP64228","article-title":"Nephrotic syndrome preceding Hodgkin\u2019s lymphoma by 13 months","volume":"64","author":"Bhatt","year":"2005","journal-title":"Clin Nephrol."},{"issue":"3","key":"B5-20260731","first-page":"125","article-title":"Spontaneously remitting minimal change nephropathy preceding a relapse of hodgkin disease by 19 months","volume":"38","author":"Korzets","year":"1992","journal-title":"Clin Nephrol."},{"issue":"5","key":"B6-20260731","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1053\/j.ajkd.2007.06.021","article-title":"Serum permeability activity in steroid-resistant minimal change nephrotic syndrome is abolished by treatment of hodgkin disease","volume":"50","author":"Aggarwal","year":"2007","journal-title":"Am J Kidney Dis."},{"issue":"3","key":"B7-20260731","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3109\/10428190109064618","article-title":"Hodgkin disease complicated by the nephrotic syndrome in a man with Kugelberg\u2013Welander disease","volume":"42","author":"Thomson","year":"2001","journal-title":"Leuk Lymphoma."},{"issue":"18","key":"B8-20260731","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1182\/blood-2009-11-251132","article-title":"Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-Mip in Hodgkin\u2013Reed-Sternberg cells and podocytes","volume":"115","author":"Audard","year":"2010","journal-title":"Blood."},{"issue":"8","key":"B9-20260731","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/j.humpath.2010.01.021","article-title":"Minimal-change nephrotic syndrome preceding Hodgkin lymphoma by 5 years with expression of tumor necrosis factor-\u03b1 in Hodgkin\u2013Reed-Sternberg cells","volume":"41","author":"Nakayama","year":"2010","journal-title":"Hum Pathol."},{"issue":"5","key":"B10-20260731","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/BF00860957","article-title":"Frequently relapsing minimal change nephrotic syndrome with natural killer cell deficiency prior to the overt relapse of Hodgkin disease","volume":"9","author":"Mori","year":"1995","journal-title":"Pediatr Nephrol."},{"issue":"12","key":"B11-20260731","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.2169\/internalmedicine.2572-23","article-title":"Minimal change nephrotic syndrome secondary to methotrexate-associated Hodgkin lymphoma","volume":"63","author":"Iimori","year":"2024","journal-title":"Intern Med."},{"issue":"8","key":"B12-20260731","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1097\/PAS.0b013e31828e6564","article-title":"Classical Hodgkin lymphoma arising in the setting of iatrogenic immunodeficiency: a clinicopathologic study of 10 cases","volume":"37","author":"Loo","year":"2013","journal-title":"Am J Surg Pathol."}],"container-title":["Kidney360"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0000001225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T19:56:08Z","timestamp":1786478168000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0000001225"}},"subtitle":["Anti\u2013Nephrin-Associated Diffuse Podocytopathy Preceding Hodgkin Lymphoma"],"short-title":[],"issued":{"date-parts":[[2026,4,20]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.34067\/kid.0000001225","relation":{},"ISSN":["2641-7650"],"issn-type":[{"value":"2641-7650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,20]]}}}