{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:07:27Z","timestamp":1791018447406,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K08DK102542"],"award-info":[{"award-number":["K08DK102542"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.34067\/kid.0004732021","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T10:01:12Z","timestamp":1632996072000},"page":"1395-1398","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Collagen Remodeling Biomarkers in Lupus Nephritis"],"prefix":"10.34067","volume":"2","clinical-trial-number":[{"clinical-trial-number":"nct02547922","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04181762","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04376827","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9106-471X","authenticated-orcid":false,"given":"Dawn J.","family":"Caster","sequence":"first","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Louisville School of Medicine, Louisville, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4128-4057","authenticated-orcid":false,"given":"Michael L.","family":"Merchant","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Louisville School of Medicine, Louisville, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,9,30]]},"reference":[{"key":"B1-20250825","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1369\/0022155419849388","article-title":"Extracellular matrix in kidney fibrosis: More than just a scaffold","volume":"67","author":"B\u00fclow","year":"2019","journal-title":"J Histochem Cytochem"},{"key":"B2-20250825","doi-asserted-by":"crossref","DOI":"10.1111\/febs.15776","article-title":"A guide to the composition and functions of the extracellular matrix","author":"Karamanos","year":"2021","journal-title":"FEBS J"},{"key":"B3-20250825","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1755-1536-7-4","article-title":"The extracellular matrix in the kidney: A source of novel non-invasive biomarkers of kidney fibrosis?","volume":"7","author":"Genovese","year":"2014","journal-title":"Fibrogenesis Tissue Repair"},{"key":"B4-20250825","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1159\/000435789","article-title":"Carriers of autosomal recessive alport syndrome with thin basement membrane nephropathy presenting as focal segmental glomerulosclerosis in later life","volume":"130","author":"Deltas","year":"2015","journal-title":"Nephron"},{"key":"B5-20250825","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41581-020-0329-y","article-title":"Complexities of the glomerular basement membrane","volume":"17","author":"Naylor","year":"2021","journal-title":"Nat Rev Nephrol"},{"key":"B6-20250825","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1681\/ASN.2013030233","article-title":"Global analysis reveals the complexity of the human glomerular extracellular matrix","volume":"25","author":"Lennon","year":"2014","journal-title":"JASN"},{"key":"B7-20250825","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.kint.2016.09.044","article-title":"Characterization of glomerular extracellular matrix by proteomic analysis of laser-captured microdissected glomeruli","volume":"91","author":"Hobeika","year":"2017","journal-title":"Kidney Int"},{"key":"B8-20250825","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1681\/ASN.2020101442","article-title":"Identification of an altered matrix signature in kidney aging and disease","volume":"32","author":"Randles","year":"2021","journal-title":"J Am Soc Nephrol"},{"key":"B9-20250825","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.kint.2017.11.023","article-title":"Revision of the International Society of Nephrology\/Renal Pathology Society classification for lupus nephritis: Clarification of definitions, and modified National Institutes of Health activity and chronicity indices","volume":"93","author":"Bajema","year":"2018","journal-title":"Kidney Int"},{"key":"B10-20250825","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1053\/j.ackd.2019.09.001","article-title":"Utilization of biomarkers in lupus nephritis","volume":"26","author":"Caster","year":"2019","journal-title":"Adv Chronic Kidney Dis"},{"key":"B11-20250825","doi-asserted-by":"crossref","first-page":"i71","DOI":"10.1093\/ndt\/gfw300","article-title":"Biomarkers of lupus nephritis histology and flare: Deciphering the relevant amidst the noise","volume":"32","author":"Birmingham","year":"2017","journal-title":"Nephrol Dial Transplant"},{"key":"B12-20250825","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1002\/acr.22762","article-title":"Development of a novel renal activity index of lupus nephritis in children and young adults","volume":"68","author":"Brunner","year":"2016","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"B13-20250825","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1177\/0961203316684212","article-title":"Prospective validation of a novel renal activity index of lupus nephritis","volume":"26","author":"Gulati","year":"2017","journal-title":"Lupus"},{"key":"B14-20250825","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1681\/ASN.2020030286","article-title":"Extracellular matrix injury of kidney allografts in antibody-mediated rejection: A proteomics study","volume":"31","author":"Clotet-Freixas","year":"2020","journal-title":"JASN"},{"key":"B15-20250825","doi-asserted-by":"crossref","first-page":"17328","DOI":"10.1038\/s41598-017-17470-3","article-title":"Urinary endotrophin predicts disease progression in patients with chronic kidney disease","volume":"7","author":"Rasmussen","year":"2017","journal-title":"Sci Rep"},{"key":"B16-20250825","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1093\/ndt\/gfv301","article-title":"Turnover of type III collagen reflects disease severity and is associated with progression and microinflammation in patients with IgA nephropathy","volume":"31","author":"Genovese","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"B17-20250825","first-page":"gfab163","article-title":"Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis","author":"Sparding","year":"2021","journal-title":"Nephrol Dial Transplant"},{"key":"B18-20250825","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1053\/j.ajkd.2019.10.017","article-title":"Update on lupus nephritis: Core curriculum 2020","volume":"76","author":"Parikh","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"B19-20250825","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1002\/art.39026","article-title":"Predictors of long-term renal outcome in lupus nephritis trials: Lessons learned from the Euro-Lupus Nephritis cohort","volume":"67","author":"Dall'Era","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"B20-20250825","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1136\/annrheumdis-2014-206897","article-title":"Long-term follow-up of the MAINTAIN Nephritis Trial, comparing azathioprine and mycophenolate mofetil as maintenance therapy of lupus nephritis","volume":"75","author":"Tamirou","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"B21-20250825","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.2147\/JIR.S301356","article-title":"Anti-TWEAK antibody alleviates renal interstitial fibrosis by increasing PGC-1\u03b1 expression in lupus nephritis","volume":"14","author":"Xue","year":"2021","journal-title":"JIR"},{"key":"B22-20250825","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1002\/art.21039","article-title":"Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual","volume":"52","author":"Fessler","year":"2005","journal-title":"Arthritis Rheum"},{"key":"B23-20250825","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1053\/j.ajkd.2019.01.026","article-title":"Effects of hydroxychloroquine on proteinuria in IgA nephropathy: A randomized controlled trial","volume":"74","author":"Liu","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"B24-20250825","doi-asserted-by":"crossref","first-page":"645100","DOI":"10.3389\/fimmu.2021.645100","article-title":"Hydroxychloroquine inhibits macrophage activation and attenuates renal fibrosis after ischemia-reperfusion injury","volume":"12","author":"Zheng","year":"2021","journal-title":"Front Immunol"},{"key":"B25-20250825","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/ckj\/sfz174","article-title":"Imbalanced turnover of collagen type III is associated with disease progression and mortality in high-risk chronic kidney disease patients","volume":"14","author":"Genovese","year":"2021","journal-title":"Clin Kidney J"},{"key":"B26-20250825","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.2337\/dc18-2599","article-title":"Markers of collagen formation and degradation reflect renal function and predict adverse outcomes in patients with type 1 diabetes","volume":"42","author":"Pilemann-Lyberg","year":"2019","journal-title":"Diabetes Care"},{"key":"B27-20250825","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.3390\/jcm9103216","article-title":"Biopsy-controlled non-invasive quantification of collagen type VI in kidney transplant recipients: A post-hoc analysis of the MECANO trial","volume":"9","author":"Yepes-Calder\u00f3n","year":"2020","journal-title":"JCM"}],"container-title":["Kidney360"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0004732021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:02:25Z","timestamp":1786478545000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0004732021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.34067\/kid.0004732021","relation":{},"ISSN":["2641-7650"],"issn-type":[{"value":"2641-7650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"2021-07-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}