{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:01:01Z","timestamp":1788930061658,"version":"build-2803163510"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Key Points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Low urinary citrate and crystal deposition accelerated cystogenesis in an experimental model of polycystic kidney disease (PKD).<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Hypocitraturia, frequently observed in patients with autosomal dominant PKD (ADPKD) could contribute to disease progression.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Present findings suggest lower urinary citrate in early PKD was associated with faster eGFR decline and worse kidney survival.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.34067\/kid.0004772022","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T18:10:22Z","timestamp":1666030222000},"page":"2110-2115","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Urinary Citrate Is Associated with Kidney Outcomes in Early Polycystic Kidney Disease"],"prefix":"10.34067","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7783-3778","authenticated-orcid":false,"given":"Daniel Ribeiro","family":"Rocha","sequence":"first","affiliation":[{"name":"Division of Nephrology, Universidade Federal de S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0837-6056","authenticated-orcid":false,"given":"Laixi","family":"Xue","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiago Murilo","family":"Gomes Sousa","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Universidade Federal de S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Christina","family":"Carvalho Matos","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Universidade Federal de S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewout J.","family":"Hoorn","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4568-8967","authenticated-orcid":false,"given":"Mahdi","family":"Salih","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0885-5877","authenticated-orcid":false,"given":"Ita Pfeferman","family":"Heilberg","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Universidade Federal de S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"B1-20250825","doi-asserted-by":"crossref","first-page":"838","DOI":"10.2215\/CJN.03100608","article-title":"Evaluation of nephrolithiasis in autosomal dominant polycystic kidney disease patients","volume":"4","author":"Nishiura","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"B2-20250825","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0272-6386(12)80922-X","article-title":"Renal stone disease in autosomal dominant polycystic kidney disease","volume":"22","author":"Torres","year":"1993","journal-title":"Am J Kidney Dis"},{"key":"B3-20250825","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.1172\/JCI128503","article-title":"Crystal 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