{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:50:33Z","timestamp":1792122633931,"version":"4.4.0"},"reference-count":90,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>\n                    Almost half a century has elapsed since the first description of dialysis-related amyloidosis (DRA), a disorder caused by excessive accumulation of\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -2 microglobulin (B2M). Within that period, substantial advances in RRT occurred. These improvements have led to a decrease in the incidence of DRA. In many countries, DRA is considered a \u201cdisappearing act\u201d or complication. Although the prevalence of patients living with RRT increases, not all will have access to kidney transplantation. Consequently, the number of patients requiring interventions for treatment of DRA is postulated to increase. This postulate has been borne out in Japan, where the number of patients with ESKD requiring surgery for carpal tunnel continues to increase. Clinicians treating patients with ESKD have treatment options to improve B2M clearance; however, there is a need to identify ways to translate improved B2M clearance into improved quality of life for patients undergoing long-term dialysis.\n                  <\/jats:p>","DOI":"10.34067\/kid.0004922020","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T19:45:11Z","timestamp":1603309511000},"page":"1447-1455","source":"Crossref","is-referenced-by-count":61,"title":["Beta-2 Microglobulin Amyloidosis: Past, Present, and Future"],"prefix":"10.34067","volume":"1","author":[{"given":"Ignacio","family":"Portales-Castillo","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry","family":"Yee","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Mihara Red Cross Hospital, Mihara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew Z.","family":"Fenves","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"issue":"Suppl 1","key":"B1-20230821","doi-asserted-by":"crossref","first-page":"A7","DOI":"10.1053\/j.ajkd.2019.01.001","article-title":"Us renal data system 2018 annual data report: Epidemiology of kidney disease in the United States","volume":"73","author":"Saran","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"B2-20230821","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1056\/NEJMra0902710","article-title":"Hemodialysis","volume":"363","author":"Himmelfarb","year":"2010","journal-title":"N Engl J Med"},{"key":"B3-20230821","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1136\/pgmj.51.597.450","article-title":"Carpal tunnel syndrome in patients on intermittent haemodialysis","volume":"51","author":"Warren","year":"1975","journal-title":"Postgrad Med J"},{"key":"B4-20230821","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1136\/jnnp.40.5.511","article-title":"Carpal tunnel syndrome related to antebrachial Cimino-Brescia fistula","volume":"40","author":"Harding","year":"1977","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B5-20230821","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1002\/art.1780280913","article-title":"Synovial amyloidosis in patients undergoing long-term hemodialysis","volume":"28","author":"Bardin","year":"1985","journal-title":"Arthritis Rheum"},{"key":"B6-20230821","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0272-6386(86)80133-0","article-title":"Carpal tunnel syndrome with cystic bone lesions secondary to amyloidosis in chronic hemodialysis patients","volume":"7","author":"Fenves","year":"1986","journal-title":"Am J Kidney Dis"},{"key":"B7-20230821","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/ki.1986.196","article-title":"Beta 2-microglobulin: A new form of amyloid protein associated with chronic hemodialysis","volume":"30","author":"Gejyo","year":"1986","journal-title":"Kidney Int"},{"key":"B8-20230821","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1093\/ajcp\/88.3.302","article-title":"Beta 2-microglobulin amyloidosis (AB2M) in patients undergoing long-term hemodialysis. A new type of amyloid","volume":"88","author":"Fuchs","year":"1987","journal-title":"Am J Clin Pathol"},{"key":"B9-20230821","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000167505","article-title":"Visceral involvement of dialysis amyloidosis","volume":"7","author":"Campistol","year":"1987","journal-title":"Am J Nephrol"},{"key":"B10-20230821","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1093\/ndt\/gfv318","article-title":"\u03b22 microglobulin amyloidosis: An update 30 years later","volume":"31","author":"Jadoul","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"B11-20230821","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1177\/039139880703001003","article-title":"Is \u03b22-microglobulin-related amyloidosis of hemodialysis patients a multifactorial disease? A new pathogenetic approach","volume":"30","author":"Cianciolo","year":"2007","journal-title":"Int J Artif Organs"},{"key":"B12-20230821","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/sj.ki.5001640","article-title":"Superior dialytic clearance of beta(2)-microglobulin and p-cresol by high-flux hemodialysis as compared to peritoneal dialysis","volume":"70","author":"Evenepoel","year":"2006","journal-title":"Kidney Int"},{"key":"B13-20230821","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3233\/BMR-130375","article-title":"The upper extremity musculoskeletal complications in dialysis patients: Comparison between hemodialysis and peritoneal dialysis","volume":"26","author":"Soyupek","year":"2013","journal-title":"J Back Musculoskeletal Rehabil"},{"key":"B14-20230821","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1038\/ki.1997.262","article-title":"Histological prevalence of \u03b2 2-microglobulin amyloidosis in hemodialysis: A prospective post-mortem study","volume":"51","author":"Jadoul","year":"1997","journal-title":"Kidney Int"},{"key":"B15-20230821","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/hdi.12057","article-title":"Impact of advanced dialysis technology on the prevalence of dialysis-related amyloidosis in long-term maintenance dialysis patients","volume":"18","author":"Schiffl","year":"2014","journal-title":"Hemodial Int"},{"key":"B16-20230821","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.carpath.2019.05.002","article-title":"The pathology and changing epidemiology of dialysis-related cardiac beta-2 microglobulin amyloidosis","volume":"42","author":"Morris","year":"2019","journal-title":"Cardiovasc Pathol"},{"key":"B17-20230821","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1038\/ki.1997.431","article-title":"Beta 2-microglobulin associated amyloidosis: A vanishing complication of long-term hemodialysis?","volume":"52","author":"Schwalbe","year":"1997","journal-title":"Kidney Int"},{"key":"B18-20230821","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/ndt\/gfv276","article-title":"Significance of the decreased risk of dialysis-related amyloidosis now proven by results from Japanese nationwide surveys in 1998 and 2010","volume":"31","author":"Hoshino","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"B19-20230821","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s41100-019-0205-z","article-title":"The features of bone articular lesions in dialysis-related amyloidosis (dra) and criteria for the clinical diagnosis of dra","volume":"5","author":"Nishi","year":"2019","journal-title":"Renal Replacement Therapy"},{"issue":"Suppl 1","key":"B20-20230821","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1097\/SAP.0000000000002181","article-title":"Incidence and risk of carpal tunnel syndrome in end-stage renal disease patients on dialysis: A nationwide population-based matched cohort study","volume":"84","author":"Tsai","year":"2020","journal-title":"Ann Plast Surg"},{"key":"B21-20230821","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1681\/ASN.2006060636","article-title":"Chronic kidney disease prevalence and treated end-stage renal disease incidence: A complex relationship","volume":"17","author":"Stengel","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"B22-20230821","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00774-019-01028-6","article-title":"Epidemiological survey and risk factor analysis of dialysis-related amyloidosis including destructive spondyloarthropathy, dialysis amyloid arthropathy, and carpal tunnel syndrome","volume":"38","author":"Tagami","year":"2020","journal-title":"J Bone Miner Metab"},{"key":"B23-20230821","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/0006-291X(85)90198-6","article-title":"In vitro formation of amyloid fibrils from intact \u03b2 2-microglobulin","volume":"131","author":"Connors","year":"1985","journal-title":"Biochem Biophys Res Commun"},{"key":"B24-20230821","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/ki.1989.25","article-title":"Amyloid syndromes associated with hemodialysis","volume":"35","author":"Kleinman","year":"1989","journal-title":"Kidney Int"},{"key":"B25-20230821","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1073\/pnas.82.12.4225","article-title":"Three-dimensional structure of beta 2-microglobulin","volume":"82","author":"Becker","year":"1985","journal-title":"Proc Natl Acad Sci U S A"},{"key":"B26-20230821","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1525-139X.2006.00134.x","article-title":"Dialysis-related amyloidosis: Late finding or hidden epidemic?","volume":"19","author":"Dember","year":"2006","journal-title":"Semin Dial"},{"key":"B27-20230821","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/ki.1991.114","article-title":"Beta 2-microglobulin kinetics in end-stage renal failure","volume":"39","author":"Odell","year":"1991","journal-title":"Kidney Int"},{"issue":"Suppl 1","key":"B28-20230821","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1681\/ASN.V13suppl_1s72","article-title":"Beta(2)-microglobulin amyloidosis: Effects of ultrapure dialysate and type of dialyzer membrane","volume":"13","author":"Lonnemann","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"B29-20230821","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/ki.1997.434","article-title":"Switch from conventional to high-flux membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients","volume":"52","author":"Koda","year":"1997","journal-title":"Kidney Int"},{"key":"B30-20230821","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3109\/13506129.2010.483116","article-title":"Mouse model to study human A \u03b22M amyloidosis: Generation of a transgenic mouse with excessive expression of human \u03b22-microglobulin","volume":"17","author":"Zhang","year":"2010","journal-title":"Amyloid"},{"key":"B31-20230821","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1056\/NEJMoa1201356","article-title":"Hereditary systemic amyloidosis due to Asp76Asn variant \u03b22-microglobulin","volume":"366","author":"Valleix","year":"2012","journal-title":"N Engl J Med"},{"key":"B32-20230821","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1159\/000362567","article-title":"Carpal tunnel surgery as proxy for dialysis-related amyloidosis: Results from the Japanese society for dialysis therapy","volume":"39","author":"Hoshino","year":"2014","journal-title":"Am J Nephrol"},{"key":"B33-20230821","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3109\/13506129709003833","article-title":"Establishment of a kinetic model of dialysis-related amyloid fibril extension in vitro","volume":"4","author":"Naiki","year":"1997","journal-title":"Amyloid"},{"key":"B35-20230821","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1056\/NEJMra023144","article-title":"Molecular mechanisms of amyloidosis","volume":"349","author":"Merlini","year":"2003","journal-title":"N Engl J Med"},{"key":"B36-20230821","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/art.1780090106","article-title":"Measurement of synovial fluid pH in normal and arthritic knees","volume":"9","author":"Cummings","year":"1966","journal-title":"Arthritis Rheum"},{"issue":"Suppl 1","key":"B37-20230821","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1016\/j.bone.2009.03.655","article-title":"Recent progress in understanding dialysis-related amyloidosis","volume":"45","author":"Yamamoto","year":"2009","journal-title":"Bone"},{"key":"B38-20230821","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/01.ASN.0000103228.81623.C7","article-title":"Glycosaminoglycans enhance the trifluoroethanol-induced extension of \u03b2 2-microglobulin-related amyloid fibrils at a neutral pH","volume":"15","author":"Yamamoto","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"B39-20230821","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1046\/j.1523-1755.1999.00430.x","article-title":"Histological characteristics of sternoclavicular \u03b2 2-microglobulin amyloidosis and clues for its histogenesis","volume":"55","author":"Garbar","year":"1999","journal-title":"Kidney Int"},{"key":"B40-20230821","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/jmbi.2001.4661","article-title":"Kidney dialysis-associated amyloidosis: A molecular role for copper in fiber formation","volume":"309","author":"Morgan","year":"2001","journal-title":"J Mol Biol"},{"key":"B41-20230821","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/ki.1996.119","article-title":"Modification of beta 2m with advanced glycation end products as observed in dialysis-related amyloidosis by 3-DG accumulating in uremic serum","volume":"49","author":"Niwa","year":"1996","journal-title":"Kidney Int"},{"key":"B42-20230821","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1172\/JCI116696","article-title":"Beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis","volume":"92","author":"Miyata","year":"1993","journal-title":"J Clin Invest"},{"key":"B43-20230821","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1681\/ASN.V1351296","article-title":"Receptor for advanced glycation end products on human synovial fibroblasts: Role in the pathogenesis of dialysis-related amyloidosis","volume":"13","author":"Hou","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"B44-20230821","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1172\/JCI117002","article-title":"Involvement of beta 2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis. Induction of human monocyte chemotaxis and macrophage secretion of tumor necrosis factor-alpha and interleukin-1","volume":"93","author":"Miyata","year":"1994","journal-title":"J Clin Invest"},{"key":"B45-20230821","first-page":"697","article-title":"Transforming growth factor-\u03b2 is involved in the pathogenesis of dialysis-related amyloidosis","volume":"57","author":"Matsuo","year":"2000","journal-title":"Kidney Int"},{"key":"B46-20230821","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1006\/bbrc.1997.7366","article-title":"Beta 2-microglobulin induces stromelysin production by human synovial fibroblasts","volume":"239","author":"Migita","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"B47-20230821","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1440-1797.2007.00845.x","article-title":"Increased levels of serum matrix metalloproteinase-3 in haemodialysis patients with dialysis-related amyloidosis","volume":"13","author":"Naganuma","year":"2008","journal-title":"Nephrology (Carlton)"},{"key":"B48-20230821","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1093\/ndt\/gfg093","article-title":"Assessment of vascular calcification in ESRD patients using spiral CT","volume":"18","author":"Moe","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"B49-20230821","doi-asserted-by":"crossref","first-page":"e27353","DOI":"10.1371\/journal.pone.0027353","article-title":"Characterization of the response of primary cells relevant to dialysis-related amyloidosis to \u03b22-microglobulin monomer and fibrils","volume":"6","author":"Porter","year":"2011","journal-title":"PLoS One"},{"key":"B50-20230821","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1053\/j.arrt.2003.11.003","article-title":"Beta-2 microglobulin in ESRD: An in-depth review","volume":"10","author":"Winchester","year":"2003","journal-title":"Adv Ren Replace Ther"},{"key":"B51-20230821","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1093\/ndt\/gfn706","article-title":"Characteristics of dialysis-related amyloidosis in patients on haemodialysis therapy for more than 30 years","volume":"24","author":"Otsubo","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"B52-20230821","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1001\/jamadermatol.2014.5022","article-title":"Massive subcutaneous masses on the back related to \u03b22-microglobulin amyloidosis","volume":"151","author":"Gargallo","year":"2015","journal-title":"JAMA Dermatol"},{"key":"B53-20230821","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/nep.13077","article-title":"Multicentre cross-sectional study for bone-articular lesions associated with dialysis related amyloidosis in Japan","volume":"23","author":"Nishi","year":"2018","journal-title":"Nephrology (Carlton)"},{"key":"B54-20230821","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000186832","article-title":"Clinical studies of destructive spondyloarthropathy in long-term hemodialysis patients","volume":"61","author":"Maruyama","year":"1992","journal-title":"Nephron"},{"key":"B55-20230821","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s13018-017-0697-6","article-title":"The unresolved problem of beta-2 microglobulin amyloid deposits in the intervertebral discs of long-term dialysis patients","volume":"12","author":"Tsai","year":"2017","journal-title":"J Orthop Surg Res"},{"key":"B56-20230821","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1081\/JDI-100001293","article-title":"Dialysis-related cervical amyloidoma presenting with quadriplegia","volume":"23","author":"Hsu","year":"2001","journal-title":"Ren Fail"},{"key":"B57-20230821","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1038\/ki.2012.436","article-title":"The case | A hip fracture in a hemodialysis patient. Pathologic right-hip fracture from \u03b22-microglobulin amyloidosis","volume":"83","author":"Bataille","year":"2013","journal-title":"Kidney Int"},{"key":"B58-20230821","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1046\/j.1523-1755.2003.00235.x","article-title":"Effect of \u03b2(2)-microglobulin adsorption column on dialysis-related amyloidosis","volume":"64","author":"Abe","year":"2003","journal-title":"Kidney Int"},{"key":"B59-20230821","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/ki.1997.401","article-title":"Dialysis-related amyloidosis of the tongue in long-term hemodialysis patients","volume":"52","author":"Matsuo","year":"1997","journal-title":"Kidney Int"},{"key":"B60-20230821","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/art.20917","article-title":"Gastrointestinal complications of beta2-microglobulin amyloidosis: A case report and review of the literature","volume":"53","author":"Dulgheru","year":"2005","journal-title":"Arthritis Rheum"},{"key":"B61-20230821","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1159\/000168154","article-title":"Systemic involvement of dialysis-amyloidosis","volume":"10","author":"Campistol","year":"1990","journal-title":"Am J Nephrol"},{"key":"B62-20230821","doi-asserted-by":"crossref","first-page":"S172","DOI":"10.1046\/j.1523-1755.2001.59780172.x","article-title":"Dialysis-related amyloidosis of the heart in long-term hemodialysis patients","volume":"78","author":"Takayama","year":"2001","journal-title":"Kidney Int Suppl"},{"key":"B63-20230821","doi-asserted-by":"crossref","first-page":"E4","DOI":"10.1053\/ajkd.1998.v31.pm10074578","article-title":"Fatal cardiac beta2-microglobulin amyloidosis in patients on long-term hemodialysis","volume":"31","author":"Kawano","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"B64-20230821","doi-asserted-by":"crossref","first-page":"3270","DOI":"10.1097\/01.ASN.0000100127.54107.57","article-title":"Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: The Dialysis Outcomes and Practice Patterns Study (DOPPS)","volume":"14","author":"Goodkin","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"B65-20230821","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s10157-016-1287-3","article-title":"A clinical staging score to measure the severity of dialysis-related amyloidosis","volume":"21","author":"Hoshino","year":"2017","journal-title":"Clin Exp Nephrol"},{"key":"B66-20230821","doi-asserted-by":"crossref","first-page":"765","DOI":"10.7863\/jum.2000.19.11.765","article-title":"Sonographic features of dialysis-related amyloidosis of the shoulder","volume":"19","author":"Sommer","year":"2000","journal-title":"J Ultrasound Med"},{"key":"B67-20230821","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1148\/radiology.217.2.r00nv05539","article-title":"Shoulder appearances at MR imaging in long-term dialysis recipients","volume":"217","author":"Slavotinek","year":"2000","journal-title":"Radiology"},{"key":"B68-20230821","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1001\/archinte.1987.00370080091018","article-title":"Lack of amyloid in abdominal fat aspirates from patients undergoing long-term hemodialysis","volume":"147","author":"Varga","year":"1987","journal-title":"Arch Intern Med"},{"key":"B69-20230821","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0140-6736(91)90478-8","article-title":"Imaging of haemodialysis-associated amyloidosis with 123I-serum amyloid P component","volume":"338","author":"Nelson","year":"1991","journal-title":"Lancet"},{"key":"B70-20230821","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0016-5085(99)70249-0","article-title":"Dialysis-related amyloidosis: An important cause of gastrointestinal symptoms in patients with end-stage renal disease","volume":"116","author":"Mogyorosi","year":"1999","journal-title":"Gastroenterology"},{"key":"B71-20230821","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1046\/j.1432-1327.2000.01071.x","article-title":"Production of recombinant human \u03b22-microglobulin for scintigraphic diagnosis of amyloidosis in uremia and hemodialysis","volume":"267","author":"Linke","year":"2000","journal-title":"Eur J Biochem"},{"key":"B72-20230821","first-page":"224","article-title":"Surgical treatment of hemodialysis-related shoulder arthropathy","volume":"38","author":"Takenaka","year":"1992","journal-title":"Clin Nephrol"},{"key":"B73-20230821","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1302\/0301-620X.76B6.7983120","article-title":"Amyloid bone cysts of the femoral neck. Impending fractures treated by curettage and bone grafting","volume":"76","author":"Naito","year":"1994","journal-title":"J Bone Joint Surg Br"},{"key":"B74-20230821","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1525-139x.2001.00038.x","article-title":"Dialysis-related amyloidosis after renal transplantation","volume":"14","author":"Campistol","year":"2001","journal-title":"Semin Dial"},{"key":"B75-20230821","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1053\/j.ajkd.2007.04.023","article-title":"Persistence of beta2-microglobulin amyloidosis 20 years after successful kidney transplantation","volume":"50","author":"Labriola","year":"2007","journal-title":"Am J Kidney Dis"},{"key":"B76-20230821","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/sdi.12590","article-title":"Dialysis related amyloidosis: Is it gone or should it be?","volume":"30","author":"Labriola","year":"2017","journal-title":"Semin Dial"},{"key":"B77-20230821","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1093\/ndt\/15.1.58","article-title":"beta(2)-microglobulin kinetics in nocturnal haemodialysis","volume":"15","author":"Raj","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"B78-20230821","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/sj.ki.5002750","article-title":"Impact of hemodialysis duration on the removal of uremic retention solutes","volume":"73","author":"Eloot","year":"2008","journal-title":"Kidney Int"},{"key":"B79-20230821","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1525-139X.2005.00079.x","article-title":"Kinetics of beta2-microglobulin and phosphate during hemodialysis: Effects of treatment frequency and duration","volume":"18","author":"Leypoldt","year":"2005","journal-title":"Semin Dial"},{"issue":"Suppl 1","key":"B80-20230821","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/oxfordjournals.ndt.a027964","article-title":"On-line haemodiafiltration. Remarkable removal of \u03b22-microglobulin. Long-term clinical observations","volume":"15","author":"Lornoy","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"B81-20230821","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1056\/NEJMoa021583","article-title":"Effect of dialysis dose and membrane flux in maintenance hemodialysis","volume":"347","author":"Eknoyan","year":"2002","journal-title":"N Engl J Med"},{"key":"B82-20230821","doi-asserted-by":"crossref","first-page":"436","DOI":"10.2215\/CJN.08790817","article-title":"Extended duration nocturnal hemodialysis and changes in plasma metabolite profiles","volume":"13","author":"Kalim","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"key":"B83-20230821","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3109\/13506129.2013.803463","article-title":"Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis","volume":"20","author":"Montagna","year":"2013","journal-title":"Amyloid"},{"key":"B84-20230821","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1681\/ASN.V72350","article-title":"Potential effect of metabolic acidosis on beta 2-microglobulin generation: In vivo and in vitro studies","volume":"7","author":"Sonikian","year":"1996","journal-title":"J Am Soc Nephrol"},{"key":"B85-20230821","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1525-1594.1993.tb00574.x","article-title":"A new therapeutic approach to dialysis amyloidosis: Intensive removal of \u03b2 2-microglobulin with adsorbent column","volume":"17","author":"Gejyo","year":"1993","journal-title":"Artif Organs"},{"key":"B86-20230821","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1744-9987.1998.tb00067.x","article-title":"New adsorption column (Lixelle) to eliminate \u03b22-microglobulin for direct hemoperfusion","volume":"2","author":"Furuyoshi","year":"1998","journal-title":"Ther Apher"},{"key":"B87-20230821","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1525-1594.2004.47260.x","article-title":"Arresting dialysis-related amyloidosis: A prospective multicenter controlled trial of direct hemoperfusion with a beta2-microglobulin adsorption column","volume":"28","author":"Gejyo","year":"2004","journal-title":"Artif Organs"},{"key":"B88-20230821","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1159\/000330332","article-title":"Effectiveness of \u03b2(2)-microglobulin adsorption column in treating dialysis-related amyloidosis: A multicenter study","volume":"32","author":"Kuragano","year":"2011","journal-title":"Blood Purif"},{"key":"B89-20230821","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1111\/j.1744-9987.2011.00937.x","article-title":"Long-term efficacy and safety of the small-sized \u03b22-microglobulin adsorption column for dialysis-related amyloidosis","volume":"15","author":"Yamamoto","year":"2011","journal-title":"Ther Apher Dial"},{"key":"B90-20230821","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.kint.2018.10.036","article-title":"Predilution online hemodiafiltration is associated with improved survival compared with hemodialysis","volume":"95","author":"Kikuchi","year":"2019","journal-title":"Kidney Int"},{"key":"B91-20230821","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/sdi.12850","article-title":"Public policy and programs - Missing links in growing home dialysis in the United States","volume":"33","author":"Abra","year":"2020","journal-title":"Semin Dial"}],"container-title":["Kidney360"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0004922020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T19:57:14Z","timestamp":1786478234000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.34067\/KID.0004922020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":90,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.34067\/kid.0004922020","relation":{},"ISSN":["2641-7650"],"issn-type":[{"value":"2641-7650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}