{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:36:22Z","timestamp":1787747782453,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["KL2 TR001874"],"award-info":[{"award-number":["KL2 TR001874"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Health Resources and Services"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2021,11]]},"abstract":"\n Key Points<\/jats:title>\n \n \n \n Transplanted kidneys with multiple arteries have similar delayed graft function and 90-day graft failure compared with single-artery kidneys.<\/jats:p>\n <\/jats:list-item>\n \n Deceased donor kidneys with multiple renal arteries have a longer cold ischemia time at transplantation compared with those with single arteries.<\/jats:p>\n <\/jats:list-item>\n \n Kidneys needing spatulation to single anastomoses may experience more delayed graft function than single-artery or other multiartery kidneys.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n Anatomic abnormalities increase the risk of deceased donor kidney discard, but their effect on transplant outcomes is understudied. We sought to determine the effect of multiple donor renal arteries on early outcomes after deceased donor kidney transplantation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n For this retrospective cohort study, we identified 1443 kidneys from 832 deceased donors with \u22651 kidney transplanted at our center (2006\u20132016). We compared the odds of delayed graft function and 90-day graft failure using logistic regression. To reduce potential selection bias, we then repeated the analysis using a paired-kidney cohort, including kidney pairs from 162 donors with one single-artery kidney and one multiartery kidney.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 1443 kidneys included, 319 (22%) had multiple arteries. Multiartery kidneys experienced longer cold ischemia time, but other characteristics were similar between groups. Delayed graft function (50% multiartery versus 45% one artery,\n P<\/jats:italic>\n =0.07) and 90-day graft failure (3% versus 3%,\n P<\/jats:italic>\n =0.83) were similar between groups before and after adjusting for donor and recipient characteristics. In the paired kidney analysis, cold ischemia time was significantly longer for multiartery kidneys compared with single-artery kidneys from the same donor (33.5 versus 26.1 hours,\n P<\/jats:italic>\n <0.001), but delayed graft function and 90-day graft failure were again similar between groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Compared with single-artery deceased donor kidneys, those with multiple renal arteries are harder to place, but experience similar delayed graft function and early graft failure.<\/jats:p>\n <\/jats:sec>","DOI":"10.34067\/kid.0005152021","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T17:55:14Z","timestamp":1631123714000},"page":"1819-1826","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Number of Donor Renal Arteries and Early Outcomes after Deceased Donor Kidney Transplantation"],"prefix":"10.34067","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1823-0117","authenticated-orcid":false,"given":"S. Ali","family":"Husain","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, New York"},{"name":"The Columbia University Renal Epidemiology Group, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-7615","authenticated-orcid":false,"given":"Kristen L.","family":"King","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, New York"},{"name":"The Columbia University Renal Epidemiology Group, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7343-8711","authenticated-orcid":false,"given":"Shelief","family":"Robbins-Juarez","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8190-3444","authenticated-orcid":false,"given":"Joel T.","family":"Adler","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women\u2019s Hospital, Boston, Massachusetts"},{"name":"Center for Surgery and Public Health at Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6482-8665","authenticated-orcid":false,"given":"Kasi R.","family":"McCune","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney and Pancreas Transplant Program, Columbia University College of Physicians & Surgeons, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5305-9685","authenticated-orcid":false,"given":"Sumit","family":"Mohan","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, New York"},{"name":"The Columbia University Renal Epidemiology Group, New York, New York"},{"name":"Department of Epidemiology, Mailman School of Public Health, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"B1-20250825","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/TP.0b013e31829853eb","article-title":"Health-related quality of life after solid organ transplantation: A prospective, multiorgan cohort study","volume":"96","author":"Kugler","year":"2013","journal-title":"Transplantation"},{"key":"B2-20250825","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1001\/jama.294.21.2726","article-title":"Deceased-donor characteristics and the survival benefit of kidney transplantation","volume":"294","author":"Merion","year":"2005","journal-title":"JAMA"},{"key":"B3-20250825","doi-asserted-by":"crossref","first-page":"e047263","DOI":"10.1136\/bmjopen-2020-047263","article-title":"Changes in quality of life (QoL) and other patient-reported outcome measures (PROMs) in living-donor and deceased-donor kidney transplant recipients and those awaiting transplantation in the UK ATTOM programme: A longitudinal cohort questionnaire survey with additional qualitative interviews","volume":"11","author":"Gibbons","year":"2021","journal-title":"BMJ Open"},{"key":"B4-20250825","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.kint.2018.02.016","article-title":"Factors leading to 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arteries","volume":"42","author":"Hwang","year":"2010","journal-title":"Transplant Proc"},{"key":"B12-20250825","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2215\/CJN.09170819","article-title":"Reproducibility of deceased donor kidney procurement biopsies","volume":"15","author":"Husain","year":"2020","journal-title":"Clin J Am Soc Nephrol"},{"key":"B14-20250825","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.2215\/CJN.02770319","article-title":"A donor utilization index to assess the utilization and discard of deceased donor kidneys perceived as high risk","volume":"14","author":"Brennan","year":"2019","journal-title":"Clin J Am Soc Nephrol"},{"key":"B15-20250825","doi-asserted-by":"crossref","first-page":"e1910312","DOI":"10.1001\/jamanetworkopen.2019.10312","article-title":"Association between declined offers of deceased donor kidney allograft and outcomes in kidney transplant candidates","volume":"2","author":"Husain","year":"2019","journal-title":"JAMA 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Direct"},{"key":"B19-20250825","doi-asserted-by":"crossref","first-page":"13","DOI":"10.2215\/CJN.12671117","article-title":"Compelling evidence of the need for policy change to decrease deceased donor kidney discard in the United States: Waste not want less","volume":"13","author":"Kadatz","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"key":"B20-20250825","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1111\/ajt.15396","article-title":"Accelerating kidney allocation: Simultaneously expiring offers","volume":"19","author":"Mankowski","year":"2019","journal-title":"Am J Transplant"},{"key":"B21-20250825","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1111\/j.1600-6143.2011.03741.x","article-title":"Impact of cold ischemia time on graft survival among ECD transplant recipients: A paired kidney analysis","volume":"11","author":"Kayler","year":"2011","journal-title":"Am J 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