{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:31:52Z","timestamp":1786480312439,"version":"build-2736575974"},"reference-count":58,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL152034"],"award-info":[{"award-number":["R01 HL152034"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Kidney360"],"published-print":{"date-parts":[[2022,9,29]]},"abstract":"\n Key Points<\/jats:title>\n \n \n \n Although kidney transplantation can increase risk for post-traumatic stress disorder, many recipients experience psychologic growth in response to the same stressors.<\/jats:p>\n <\/jats:list-item>\n \n Underlying characteristics such as resilience affect how recipients respond to kidney failure and transplantation.<\/jats:p>\n <\/jats:list-item>\n \n Investigators are just starting to understand the role of psychologic stress during kidney failure and transplantation.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n Kidney transplantation (KT) is a life-saving therapy for kidney failure. However, KT recipients can suffer from debilitating depression, post-traumatic stress disorder (PTSD), and suicide. In contrast to PTSD, post-traumatic growth (PTG) is a positive psychologic change in response to a challenging situation. PTG has been studied in other chronic diseases, but less is known about its role in the setting of KT. We sought to elucidate the prevalence, predictors, and the effect of PTSD and PTG on post-KT outcomes. We also considered the roles of benefit finding and resilience.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In a literature review, we identified publications that examined PTSD, PTG, benefit finding, and\/or resilience in KT recipients. We excluded case reports and first-person narratives. Publications meeting the specified criteria after full text review underwent data abstraction and descriptive analysis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Of the 1013 unique citations identified, 39 publications met our criteria. PTSD was the most common construct evaluated (16 publications). Resilience was studied in 11 publications, PTG in nine, and benefit finding in five. Up to 21% of adult and 42% of pediatric KT recipients may experience PTSD, which is associated with lower quality of life (QOL), impaired sleep, and other psychiatric comorbidity. PTG was associated with improved QOL, kidney function, and reduced risk of organ rejection. Although benefit finding tended to increase post KT, resilience remained stable post KT. Like PTG, resilience was associated with lower psychologic distress and increased treatment adherence and confidence in the health care team.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n PTG, resilience, and benefit finding appear to reduce the risk of PTSD, promote well-being, and reduce risk of graft failure in KT recipients. Future research to understand these relationships better will allow clinicians and researchers to develop interventions to promote PTG, resilience, and benefit finding, and potentially improve post-transplant outcomes such as adherence and reducing risk of organ rejection.<\/jats:p>\n <\/jats:sec>","DOI":"10.34067\/kid.0008152021","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T17:45:11Z","timestamp":1659375911000},"page":"1590-1598","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":22,"title":["Post-Traumatic Stress Disorder and Post-Traumatic Growth following Kidney Transplantation"],"prefix":"10.34067","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7181-105X","authenticated-orcid":false,"given":"Rebekah P.","family":"Nash","sequence":"first","affiliation":[{"name":"Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-6342","authenticated-orcid":false,"given":"Marci M.","family":"Loiselle","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2685-0962","authenticated-orcid":false,"given":"Jessica L.","family":"Stahl","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3527-9975","authenticated-orcid":false,"given":"Jamie L.","family":"Conklin","sequence":"additional","affiliation":[{"name":"Health Science Library, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-7173","authenticated-orcid":false,"given":"Terra L.","family":"Rose","sequence":"additional","affiliation":[{"name":"Division of Clinical Rehabilitation and Mental Health Counseling, Department of Allied Health Sciences, University of North Carolina School of Medicine, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alissa","family":"Hutto","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1414-1846","authenticated-orcid":false,"given":"Donna M.","family":"Evon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4596-8536","authenticated-orcid":false,"given":"Jennifer E.","family":"Flythe","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina Kidney Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina"},{"name":"Cecil G. Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8045-7507","authenticated-orcid":false,"given":"Eileen J.","family":"Burker","sequence":"additional","affiliation":[{"name":"Division of Clinical Rehabilitation and Mental Health Counseling, Department of Psychiatry and Department of Allied Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"B1-20250825","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1159\/000495081","article-title":"Trends in the causes of death among kidney transplant recipients in the United States (1996\u20132014)","volume":"48","author":"Awan","year":"2018","journal-title":"Am J 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