{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:52:28Z","timestamp":1791118348970,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nuklearmedizin"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>\n          Purpose: To evaluate the accuracy of retrospective rigid image registration and fusion between F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) of the upper abdomen. Patients, material, methods: Image fusion of PET and MRI was performed in 30 patients with suspected malignancy of the liver or pancreas. Using a commercially available image fusion tool capable of rigid manual point-based registration, PET-Images were retrospectively registered and fused by matching eight homologous points in the 3D spoiled gradient echo (GRE) MRI sequences acquired in portal venous phase and in the CT-component of PET\/CT. Two separate observers (R1, R2) assessed accuracy of image registration by determining the distances in the x-, y- and z-axis as well as the absolute distance between anatomical landmarks which differed from the landmarks chosen for registration. Quality of fusion was graded using a three point grading scale (1 poorly fused; 2 satisfactory fused; 3 correctly fused) and compared to hybrid PET\/CT fusion. Results: Mean time of registration per patient was less than 2 minutes. Objective registration assessment showed errors between 2.4\u20136.3 mm in x-axis: mean 3.6 mm (R1); 4.6 mm (R2), 2.3\u20139.3 mm in y-axis (mean 5.1 mm; 5.5 mm) and 3.3\u201312.0 mm in z-axis (mean 5.9 mm; 5.9 mm.) The mean error in absolute distance between points was 6.0\u201316.8 mm (mean 9.9 mm; 10.6 mm). In visual assessment, most fusions were graded to be satisfactory or correctly fused: R1, R2: grade 3, 11\/30 (36.7%), 22\/30 (73.3%); grade 2, 13\/30 (43.3%), 8\/30 (26.7%); grade 1, 6\/30 (20%), 0\/30 (0%). Fusions were mostly comparable to hybrid PET\/ CT fusions. All of the fusions were defined as diagnostically relevant by both observers. Conclusion: Retrospective rigid image fusion of FDGPET and MRI of the upper abdomen using the CT-component of PET\/CT for registration is feasible without adaptation in image acquisition protocols and shows sub-centimeter registration errors in most cases.<\/jats:p>","DOI":"10.3413\/nukmed-0263","type":"journal-article","created":{"date-parts":[[2010,4,21]],"date-time":"2010-04-21T09:03:55Z","timestamp":1271840635000},"page":"106-114","source":"Crossref","is-referenced-by-count":13,"title":["18F-FDG-PET and MRI in patients with malignancies of the liver and pancreas"],"prefix":"10.3413","volume":"49","author":[{"given":"C. S.","family":"Reiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. F.","family":"Hany","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Fornaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. K.","family":"von Schulthess","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Marincek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Weishaupt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. F.","family":"Donati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,1,24]]},"container-title":["Nuklearmedizin"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.3413\/nukmed-0263.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T16:24:35Z","timestamp":1540398275000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.3413\/nukmed-0263"}},"subtitle":["Accuracy of retrospective multimodality image registration by using the CT-component of PET\/CT"],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,1,25]]},"published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.3413\/nukmed-0263","relation":{},"ISSN":["0029-5566","2567-6407"],"issn-type":[{"value":"0029-5566","type":"print"},{"value":"2567-6407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}