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These unobserved mechanical signatures may contribute to clinically relevant failure modes, including missed lesions, incomplete resection, and adverse events driven by excessive wall loading. Inspired by the tactile sensing mechanisms of rat whiskers, this study introduces a bionic multichannel whisker system, as an additional sensing modality for endoluminal interventions. The system integrates high-fidelity tactile sensing hardware, and advanced signal processing algorithms, enabling precise and reliable measurements of tissue properties, as well as providing real-time radial force feedback. Calibration via affine transformation ensures cross-channel consistency and compensates for manufacturing and installation variances. Validation across multiple experimental settings, including robotic and manual operation, demonstrates performance in texture discrimination, shape reconstruction, and radial force estimation. The presented whisker system is compact to support integration with endoscopic instruments, providing a practical basis for complementing endoluminal diagnostic workflows and for further development of tactile sensing in surgical robotics.<\/jats:p>","DOI":"10.34133\/cbsystems.0616","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T07:47:31Z","timestamp":1778831251000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["A Bionic Multichannel Whisker System for Assisting Endoluminal Intervention"],"prefix":"10.34133","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2664-558X","authenticated-orcid":false,"given":"Zeyu","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Surgery and Cancer, Faculty of Medicine, \rImperial College London, London SW7 2AZ, UK."},{"name":"Department of Electrical and Electronic Engineering, Faculty of Engineering, \rImperial College London, London SW7 2AZ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank P.-W.","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer, Faculty of Medicine, \rImperial College London, London SW7 2AZ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer, Faculty of Medicine, \rImperial College London, London SW7 2AZ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianing","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Personalized Medicine, Mohamed bin Zayed University of Artificial Intelligence, \rBuilding 1B, Masdar City, P.O. 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