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However, despite some technological solutions already in place, their adoption has been hindered by the lack of usability, especially in the set-up process. Objectives: In this article we propose a tele-medicine platform that relies on a cloud computing infrastructure and social media principles to simplify the creation of dynamic user-based groups, opening up opportunities for the establishment of teleradiology trust domains.<\/jats:p><jats:p>Methods: The collaborative platform is provided as a Software-as-a-Service solution, supporting real time and asynchronous collaboration between users. To evaluate the solution, we have deployed the platform in a private cloud infrastructure. The system is made up of three main components \u2013 the collaborative framework, the Medical Management Information System (MMIS) and the HTML5 (Hyper Text Markup Language) Web client application \u2013 connected by a message-oriented middleware.<\/jats:p><jats:p>Results: The solution allows physicians to create easily dynamic network groups for synchronous or asynchronous cooperation. The network created improves dataflow between colleagues and also knowledge sharing and cooperation through social media tools. The platform was implemented and it has already been used in two distinct scena -rios: teaching of radiology and tele-reporting.<\/jats:p><jats:p>Conclusions: Collaborative systems can simplify the establishment of telemedicine expert groups with tools that enable physicians to improve their clinical practice. Stream -lining the usage of this kind of systems through the adoption of Web technologies that are common in social media will increase the quality of current solutions, facilitating the sharing of clinical information, medical imaging studies and patient diagnostics among collaborators.<\/jats:p>","DOI":"10.3414\/me14-01-0052","type":"journal-article","created":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T09:09:08Z","timestamp":1457082548000},"page":"203-214","source":"Crossref","is-referenced-by-count":7,"title":["A Cloud Architecture for Teleradiology-as-a-Service"],"prefix":"10.3414","volume":"55","author":[{"given":"Carlos","family":"Costa","sequence":"first","affiliation":[]},{"given":"Jos\u00e9","family":"Oliveira","sequence":"first","affiliation":[]},{"given":"Eriksson","family":"Mel\u00edcio Monteiro","sequence":"additional","affiliation":[]}],"member":"194","published-online":{"date-parts":[[2018,1,8]]},"reference":[{"key":"10.3414\/ME14-01-0052-1","unstructured":"Montagnant J, Duque H, Pierson JM, Breton V, Brunie L, Magnin IE. 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