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Two nasopharyngeal and oropharyngeal throat swab samples were collected from each patient and tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using real-time reverse-transcriptase\u2013 polymerase-chain-reaction (RT-PCR). The samples were also tested for influenza viruses and the complete respiratory panel. Results: In the present report, four patients were diagnosed in the starting days of COVID-19 disease in our center in southern Iran with co-infection of SARS-CoV-2 and influenza A virus. Conclusion: This co-infection of COVID-19 and influenza A highlights the importance of considering SARS-CoV-2 PCR assay regardless of other positive findings for other pathogens in the primary test during the epidemic.<\/jats:p>","DOI":"10.34172\/aim.2020.04","type":"journal-article","created":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T12:56:40Z","timestamp":1586437000000},"page":"239-243","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":77,"title":["Co-infection of Coronavirus Disease 2019 and Influenza A: A Report from Iran"],"prefix":"10.34172","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4876-4312","authenticated-orcid":true,"given":"Zohre","family":"Khodamoradi","sequence":"first","affiliation":[{"name":"Department of internal medicine, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran"},{"name":"Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8015-0313","authenticated-orcid":true,"given":"Mohsen","family":"Moghadami","sequence":"additional","affiliation":[{"name":"Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrzad","family":"Lotfi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20123","published-online":{"date-parts":[[2020,4,1]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001191"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1405858"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30260-9"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-015-0450-0"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Hoehl S, Berger A, Kortenbusch M, Cinatl J, Bojkova D, Rabenau H, et al. 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