{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T15:37:02Z","timestamp":1766158622944,"version":"3.37.3"},"reference-count":0,"publisher":"Maad Rayan Publishing Company","issue":"11","content-domain":{"domain":["www.aimjournal.ir"],"crossmark-restriction":false},"short-container-title":["Arch Iran Med"],"abstract":"<jats:p>\n            <jats:bold>Background: <\/jats:bold>The aim of this study was to identify gastrointestinal (GI) and liver injury presentations in children admitted with COVID-19 infection. <jats:bold>Methods:<\/jats:bold> In this retrospective study, we studied all children with suspected symptoms of COVID-19, referred to Amirkola Children\u2019s Hospital. Clinical manifestations of the digestive and respiratory systems and liver function tests were evaluated for all cases. <jats:bold>Results:<\/jats:bold> Eighteen children were studied. The most common clinical symptoms were fever, anorexia, weakness, nausea and vomiting, cough, diarrhea, and abdominal pain, respectively. Also, 5\/18 (27.8%) and 7\/18 (38.9%) of cases had abnormally high alanine aminotransferase (ALT), aspartate aminotransferase (AST), respectively. Additionally, in icteric cases, direct bilirubin was raised. There was no significant relationship between pulmonary lesions and abnormal excess in ALT (<jats:italic>P<\/jats:italic> = 0.59) and AST (<jats:italic>P<\/jats:italic> = 0.62). <jats:bold>Conclusion: <\/jats:bold>The findings showed that there were no severe clinical GI symptoms in children with COVID-19 infection. Besides, children with increased liver enzymes did not have more respiratory involvement than those without a rise in liver enzymes.<\/jats:p>","DOI":"10.34172\/aim.2020.104","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T15:22:44Z","timestamp":1605108164000},"page":"782-786","update-policy":"https:\/\/doi.org\/10.34172\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["COVID-19 and Digestive System in Children: A Retrospective Study"],"prefix":"10.34172","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0815-4499","authenticated-orcid":true,"given":"Mohammadreza","family":"Esmaeili Dooki","sequence":"first","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2062-0448","authenticated-orcid":true,"given":"Sanaz","family":"Mehrabani","sequence":"additional","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Sorkhi","sequence":"additional","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Nikpour","sequence":"additional","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamadreza","family":"Tabatabaie","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Amirkola Children\u2019s Hospital, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohsen","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masood","family":"Kiani","sequence":"additional","affiliation":[{"name":"Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2020,11,1]]},"container-title":["Archives of Iranian Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.aimjournal.ir\/PDF\/aim-23-782.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.aimjournal.ir\/PDF\/aim-23-782.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T15:22:44Z","timestamp":1605108164000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.aimjournal.ir\/Article\/aim-18700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,11]]}},"URL":"https:\/\/doi.org\/10.34172\/aim.2020.104","relation":{},"ISSN":["1029-2977","1735-3947"],"issn-type":[{"type":"print","value":"1029-2977"},{"type":"electronic","value":"1735-3947"}],"subject":[],"published":{"date-parts":[[2020,11,1]]},"assertion":[{"value":"Academy of Medical Sciences of the I.R. Iran","name":"journal_owner","label":"Journal Owner"},{"value":"Academy of Medical Sciences of the I.R. Iran","name":"journal_publisher","label":"Journal Publisher"}]}}